Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,069 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02897700RecruitingPhase 1
Testing chemotherapy choices for early breast cancer after surgery
This Phase 1 study tests different chemotherapy approaches in people with breast cancer that has been surgically removed but is early stage. It aims to find a chemotherapy plan that’s safe and works well right after surgery.
Ganzhou, JiangxiAges 18 years+ - NCT06366828Recruiting
Predicting complications after esophageal cancer treatment
This study looks at past medical records of people with esophageal cancer who received chemotherapy and radiation before surgery. Researchers want to find better ways to predict who might have complications after surgery, so they can improve care for future patients.
Nijmegen, GelderlandAges 18–100 - NCT06402188Recruiting
ColoSeal Device Study for Rectal Cancer Surgery
This study tests a new device called the ColoSeal ICD System that may help protect the reconnection of your bowel after surgery for rectosigmoid or rectal cancer. It is designed for people who are already scheduled for surgery that includes a temporary colostomy or ileostomy.
YerevanAges 18–70 - NCT04442516Recruiting
Testing kidney injury risk from cisplatin cancer treatment
This study looks at how cisplatin chemotherapy affects the kidneys. It may help doctors better predict and protect against kidney damage when patients start cisplatin.
London, OntarioAges 3 months+ - NCT05117723Recruiting
IPMN cyst database to help predict pancreatic cancer risk
This study collects information from people who have an IPMN cyst in the pancreas to help predict who may be at higher risk of pancreatic cancer. It may help your care team estimate risk and plan follow-up more effectively.
Fitzroy, VictoriaAges 18–90 - NCT06360042RecruitingPhase 2
Immunotherapy plus anti-angiogenic drugs for advanced liver cancer
This trial is testing a combination of immunotherapy (anti-PD-1/PD-L1) and drugs that block blood vessel growth (anti-angiogenic agents) as a first treatment for people with advanced liver cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06280508RecruitingPhase 2
Perioperative chemo plus immunotherapy for bile duct cancer
This trial tests a combination of chemotherapy, immunotherapy (adebrelimab), and a targeted therapy (apatinib) before and after surgery for bile duct cancer that can be removed and has a high risk of coming back. It aims to see if this approach can lower the chance of recurrence.
Guangzhou, China/GuangdongAges 18 years+ - NCT06369181Recruiting
Study on cell changes in lung cancer with RB1/TP53 gene changes
This trial looks at what happens when certain types of non-small cell lung cancer—those with changes in the RB1 and TP53 genes—start to change into another type of lung cancer after treatment. It may help find better ways to treat this specific kind of cancer in the future.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03659448RecruitingPhase 3
Test drug that helps map colon and rectal cancer during surgery
This Phase 3 study tests SGM-101, a drug used during surgery to help doctors better outline primary, recurrent, and spread (metastatic) colorectal cancer. It may improve how completely tumors are identified and removed during an operation.
Duarte, CaliforniaAges 18 years+ - NCT03767075RecruitingPhase 2
Basket trial matching cancer patients to targeted treatments
This trial tests whether matching your tumor’s DNA/RNA results to a specific cancer medicine can work better than standard options when cancer has spread or can’t be removed by surgery. You may be assigned to a “basket” (sub-study) based on the exact changes found in your tumor.
VillejuifAges 18 years+ - NCT06257030Recruiting
Liver tumor treatment study for large tumors
This study tests a targeted radiation treatment called Y90 for liver tumors that are too large for standard approaches. It aims to see how well the treatment works for people with primary or secondary liver cancers that mainly affect the liver and have at least one tumor bigger than 5 cm.
Pátrai, AchaiaAges 18 years+ - NCT06256224Recruiting
Toripalimab with standard chemoradiation for advanced cervical cancer
This trial combines the immunotherapy drug toripalimab with standard chemoradiation to treat newly diagnosed advanced cervical cancer. It aims to see if adding toripalimab improves outcomes for patients whose cancer has not spread to distant organs.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03685890RecruitingPhase 1/Phase 2
Testing nivolumab for melanoma spread to the limb skin
This trial studies nivolumab, an immune medicine, for melanoma that has spread to the skin along a limb (called in-transit metastases). It’s given after a procedure that delivers higher treatment levels to the affected limb, with the goal of shrinking the melanoma and improving outcomes.
AmsterdamAges 18 years+ - NCT03749980Recruiting
Study following people with von Hippel-Lindau (VHL)
This study follows people who have von Hippel-Lindau (VHL) over time to better understand how the condition changes. It may help doctors plan future treatments by collecting long-term health information.
Boston, MassachusettsAges Any age - NCT06385990RecruitingPhase 2
Utidelone plus Capecitabine for residual triple-negative breast cancer
This trial tests a combination of two oral chemotherapy drugs (Utidelone and Capecitabine) for women with triple-negative breast cancer that did not fully disappear after standard chemo before surgery. The goal is to see if this treatment can lower the chance of the cancer coming back.
Changsha, HunanAges 18–70 - NCT06389422RecruitingPhase 2
Radiation plus Keytruda for liver cancer with vein clots
This trial tests a combination of moderate-dose radiation therapy and the immunotherapy drug pembrolizumab (Keytruda) for liver cancer that has spread into the main veins of the liver. It aims to see if this combination can shrink tumors and improve survival.
Beijing, Beijing MunicipalityAges 18–90 - NCT06391190RecruitingPhase 1/Phase 2
Chemoradiation plus immunotherapy for advanced cervical cancer
This trial tests combining standard chemoradiation with a PD-1 inhibitor (a drug that helps your immune system fight cancer) for advanced cervical cancer that hasn't been treated yet. The goal is to see if this combination works better than standard treatment alone.
ShanghaiAges 18–75 - NCT06389552Recruiting
Long-term study of FOLFIRINOX after pancreatic cancer surgery
This study follows people with pancreatic cancer who are receiving a chemotherapy combination called FOLFIRINOX after surgery. The goal is to see how well the treatment works over time and how it affects long-term survival and cancer recurrence.
SeoulAges 19 years+ - NCT06383728RecruitingPhase 2
Targeted therapy before surgery for EGFR-mutated lung cancer
This trial tests if taking a targeted therapy drug before surgery can help shrink tumors in people with a specific type of lung cancer called EGFR-mutated squamous cell carcinoma that can be removed with surgery. The goal is to see if this approach improves outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06397755Recruiting
Study of patients with prostate biopsy or prostate removal surgery
This study looks at patients who have had a prostate biopsy or surgery to remove the prostate (radical prostatectomy). It aims to learn more about these procedures and how patients are doing.
MilanAges 18 years+ - NCT06397287Recruiting
Urology patient feedback study
This study gathers information from urology patients using digital tools like email or apps. Your feedback could help improve care for others with urology conditions.
Graz, StyriaAges 18 years+ - NCT06218628RecruitingPhase 1
Pacritinib and talazoparib for bone marrow cancers unresponsive to prior therapy
This trial tests a combination of two drugs (pacritinib and talazoparib) for people with certain bone marrow cancers that have not responded well to standard JAK2 inhibitor therapy. The goal is to see if this combination can help shrink the spleen, improve symptoms, or slow disease progression.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06389448Recruiting
Comparing Two Imaging Methods for Stomach Lesion Diagnosis
This trial compares two special camera methods (pCLE and EB) used during endoscopy to better see and diagnose early stomach changes. It may help doctors decide the best treatment for precancerous spots or very early cancer.
Wuhan, HubeiAges 18–75 - NCT06405217Recruiting
Recombinant TSH for radioactive iodine therapy in thyroid cancer
This trial tests whether a medicine called recombinant human thyroid stimulating hormone (rhTSH) can help prepare your body for radioactive iodine (131I) treatment, which aims to destroy any remaining or spreading thyroid cancer cells. It may be a good option if your thyroid cancer has come back or spread and you are able to have radioactive iodine therapy.
Nanjing, JiangsuAges 18–75
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,069 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.