Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,042 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04849481Recruiting
Precision medicine planning for advanced lung cancer tissue testing
This trial uses your tumor sample to guide personalized treatment decisions for certain lung cancers. It may help by matching you to a more targeted plan based on genetic testing and your prior treatment history.
Chiayi CityAges 20 years+ - NCT04782752Recruiting
Radiation before lung transplant to help stop lung cancer spread
This study tests a focused, low-dose type of radiation given before a lung transplant. The goal is to help your immune system recognize and attack cancer cells (called “radiovaccination”) and improve outcomes for people who cannot get curative treatment with surgery or SBRT alone.
Toronto, OntarioAges 18 years+ - NCT04797039Recruiting
MRI-guided freezing treatment for localized prostate cancer
This trial studies a treatment where doctors use MRI pictures to guide freezing of a prostate tumor. It may help men with smaller, well-placed prostate cancers who cannot or do not want surgery or radiation right now.
Rochester, MinnesotaAges 30–100 - NCT04793633Enrolling by invitation
Testing a noninvasive way to collect pancreatic cells early
This study tests LINFU™, a noninvasive method to collect pancreatic cells to help detect pancreatic cancer earlier. You may be invited if you’re at higher risk or you have concerning symptoms and planned pancreas/bile testing (like EUS or CT).
Sarasota, FloridaAges 18–90 - NCT04777994RecruitingPhase 1
Drug ABBV-CLS-484 for advanced cancers that lack options
This Phase 1 trial tests ABBV-CLS-484 in people with advanced or metastatic tumors when standard treatments have not worked or aren’t available. Because it’s an early study, the main goal is to find a safe dose and see how the cancer responds in different cancer types.
Tucson, ArizonaAges 18 years+ - NCT04853342RecruitingPhase 3
Furmonertinib after lung tumor removal for EGFR-mutated lung cancer
This trial tests whether furmonertinib, an oral targeted medicine, can improve outcomes after your lung tumor has been completely removed. It also checks for side effects and compares results against placebo in people with specific EGFR gene mutations.
Suzhou, JiangsuAges 18–75 - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04755205Recruiting
Natural history study of olfactory neuroblastoma
This study follows people with olfactory neuroblastoma over time to better understand how the disease behaves and changes. It may help future patients by improving doctors’ knowledge, even if it does not test a new treatment.
Bethesda, MarylandAges 3–120 - NCT04717349Recruiting
Study collects health information for kids’ and teens’ gynecology concerns
This is a research study that gathers information about pediatric and adolescent gynecology conditions. It may help researchers better understand these issues by learning about symptoms, care, and outcomes—without requiring a specific treatment.
Bethesda, MarylandAges 1 day–100 years - NCT04750928RecruitingPhase 1/Phase 2
Abemaciclib for NF1 tumors using pills and body scans
This trial studies whether the medicine abemaciclib can shrink or slow the growth of “atypical neurofibromas” in people with NF1. Participants take pills and undergo regular check-ups, including MRI scans to measure the tumor.
Bethesda, MarylandAges 12 years+ - NCT04743362Recruiting
Noninvasive scans for skin and mouth lesions
This trial tests noninvasive imaging methods to look at skin and mouth (mucosal) conditions. It may help doctors better see changes in these areas without taking tissue samples.
New York, New YorkAges Any age - NCT04765514RecruitingPhase 2
Chemo with radiation versus chemo alone for older brain tumor patients
This trial compares two standard treatments for newly diagnosed glioblastoma (a serious brain cancer) in older and frail patients: chemo plus radiation versus chemo alone. It may help determine which approach works best and is safest for people in your age and health group.
Calgary, AlbertaAges 65 years+ - NCT04741997RecruitingEarly Phase 1
Adjuvant melanoma treatment guided by response to targeted drugs
This early-phase study looks at whether people with melanoma can get the “right” follow-up (extra) treatment based on how well their cancer responds after starting targeted drugs before surgery. The goal is to improve outcomes while better matching treatment to each person’s tumor response.
Tampa, FloridaAges 18 years+ - NCT04755855Recruiting
Study of treatment outcomes in sinonasal cancer patients
This study follows people who have sinonasal cancer and are being treated at Mayo Clinic. It looks at how patients do over time, which may help improve care for future patients.
Rochester, MinnesotaAges 4 weeks–99 years - NCT04757922Enrolling by invitation
Tests whether removing fallopian tubes affects menopause timing
This trial studies whether an “opportunistic salpingectomy” (removing fallopian tubes) during sterilization changes when menopause happens. It compares people who have this procedure to those who get different sterilization (tubal ligation) or none.
EindhovenAges 30–45 - NCT04738708Recruiting
Phone vs in-person genetic counseling for cancer risk
This study compares two ways of getting genetic counseling—by phone/video or in person—for people who may have hereditary cancer syndromes like HBOC or Lynch syndrome. It may help find which counseling approach works best for understanding results and next steps.
SingaporeAges 21 years+ - NCT04747054RecruitingPhase 3
Radiation plus pembrolizumab for newly diagnosed metastatic head and neck cancer
This trial studies whether adding pembrolizumab (an immune system medicine) to radiation can improve outcomes in people newly diagnosed with metastatic head and neck squamous cell cancer. It may help the immune system better recognize and fight the cancer alongside radiation.
AvignonAges 18 years+ - NCT04708054RecruitingPhase 2/Phase 3
Venetoclax with busulfan chemo for high-risk AML or MDS
This study tests whether adding venetoclax to a specific busulfan-based chemotherapy plan improves outcomes for people with high-risk AML or MDS. It mainly targets patients whose leukemia/marrow disease still has high-risk features or measurable disease after initial treatment.
Houston, TexasAges 18–70 - NCT04751396Recruiting
Melanoma education for people with autoimmune conditions
This trial tests an educational tool to help people with melanoma and pre-existing autoimmune disease understand immune checkpoint inhibitor treatment. It aims to support you and your care team with information that can help you make decisions and feel more prepared.
Houston, TexasAges 18 years+ - NCT04706481Recruiting
Use of stored, de-identified samples for research
This trial is for people who already agreed to let researchers use their stored biological samples and medical information that has been removed of personal identifiers. It may help future studies by allowing researchers to analyze existing samples without using new samples from you.
Hong KongAges Any age - NCT04749108RecruitingPhase 2/Phase 3
Tailored treatment for locally advanced rectal cancer after FOLFIRINOX
This trial studies a more customized treatment plan for people with locally advanced rectal (bowel) cancer after they receive FOLFIRINOX chemotherapy. It aims to reduce tumor spread risk and improve outcomes by tailoring the next steps based on scan details and your health status.
Marseille, Bouches Du RhôneAges 18 years+ - NCT04744116RecruitingEarly Phase 1
Cord blood cell therapy added to ruxolitinib for steroid-resistant GVHD
This trial studies whether adding cord-blood–derived cells to ruxolitinib can improve steroid-resistant acute graft-versus-host disease (GVHD) affecting the lower gut or liver. It’s meant for people who are not getting better (or are worsening) despite adequate steroid treatment.
Houston, TexasAges 12–80 - NCT04745949RecruitingPhase 2
Testing first-line antibody plus immunotherapy for mediastinal lymphoma
This trial tests a combination of antibody therapy and immunotherapy (plus standard chemo) as first treatment for primary mediastinal large B-cell lymphoma. It may help shrink the lymphoma and improve how long patients stay in remission.
Houston, TexasAges 18 years+ - NCT04690374Recruiting
Registry to Track Health Information in Desmoplastic Tumor
This registry collects health information from people diagnosed with desmoplastic small round cell tumor. Your information helps doctors and researchers better understand the illness over time.
New York, New YorkAges Any age
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,042 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.