Clinical trials
Cannabis Use clinical trials
Below are recruiting cannabis use clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05581368Recruiting
Study how cannabis affects blood vessels
This trial tests whether regular cannabis use changes how your blood vessels work, compared with people who do not use cannabis. It may help researchers understand potential effects on heart and circulation health.
London, OntarioAges 19–80 - NCT06863740Recruiting
Cannabis for Restless Legs Syndrome
This study tests whether cannabis can help people with Restless Legs Syndrome that has not improved with standard treatments. If you have RLS and other treatments haven't worked well, you may be able to join.
Toronto, OntarioAges 25 years+ - NCT04935619Recruiting
Testing cannabis abstinence effects in depression symptoms
This study looks at how stopping cannabis for a period of time may affect depression symptoms and thinking/memory. You might benefit by getting close monitoring of mood and cognition while researchers compare changes during cannabis abstinence.
Toronto, OntarioAges 18–55 - NCT07001878RecruitingPhase 4
Cannabis Strength and Brain Health in Early Psychosis
This trial studies how different strengths of cannabis affect the brain's white matter in people with early psychosis. It may help doctors understand which cannabis potencies are less harmful for young adults with psychosis.
St. John's, Newfoundland and LabradorAges 18–25 - NCT06446479RecruitingPhase 2
THC's effect on alcohol use and brain reward
This study tests whether THC (the active ingredient in cannabis) can change how much alcohol you drink and how your brain responds to rewards. You will have MRI scans and take THC or a placebo, then drink alcohol in a controlled setting.
Aurora, ColoradoAges 21–40 - NCT07524985Recruiting
Cannabis Use Study: Understanding Effects in Daily Users
This study looks at how cannabis affects people who use it regularly in their daily lives. Researchers will use a smartphone app to track your experiences and better understand cannabis use in the general population.
Montreal, QuebecAges 18 years+ - NCT06699251Recruiting
Brief chat with your doctor about alcohol or cannabis for teens
This study tests whether a short, one-time conversation with a primary care provider can help teens who are at risk for alcohol or cannabis use. It's designed for young people ages 12–17 who get care at two specific health systems.
Commerce, CaliforniaAges 12–19 - NCT06430580RecruitingEarly Phase 1
Cannabinoids and stress response in heavy cannabis users
This early-phase study tests how cannabinoids affect your body's reaction to stress. If you use cannabis daily and have cannabis use disorder, you may be able to join to help researchers understand these effects better.
Tallahassee, FloridaAges 18–50 - NCT03332966Recruiting
Study of teens’ experiences in mental health care
This study looks at how young people experience mental health clinic care and how that relates to health outcomes. You may be invited if you are starting care in an adolescent mental health clinic.
HelsinkiAges 15–18 - NCT03995121Recruiting
Brain scan study using a PET tracer
This study tests how a special PET scan tracer behaves in your brain. It may help researchers better understand brain activity and improve imaging for future studies.
New Haven, ConnecticutAges 18–85 - NCT04883255RecruitingEarly Phase 1
Study cannabis effects on brain function in adults with HIV
This early-phase study looks at how cannabis (and the body’s cannabinoid system) may affect thinking and brain-related measures in people with HIV. You may be asked to avoid cannabis and complete several brain and health assessments to see how these factors relate.
San Diego, CaliforniaAges 18–65 - NCT05119244Recruiting
Study of environment factors in lung cancer
This study looks at how environmental factors may relate to lung cancer in adults. If you are between 18 and 59 and were treated for primary lung cancer at a participating hospital, you may be able to join.
Le Plessis-RobinsonAges 18–59 - NCT05465538RecruitingPhase 1/Phase 2
PET imaging study using SV2A in older adults
This early-phase study tests a PET scan tracer called SV2A in adults age 50 and older. It aims to help researchers understand how the tracer works in the brain/body, which could support future diagnostic or treatment research.
New Haven, ConnecticutAges 50 years+ - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT06037681Recruiting
Study on cannabis use and pain outcomes in Black and white patients with cancer
This study looks at how cannabis affects pain and daily life in Black and white patients with solid tumors. It compares people who use cannabis at least once a week to those who don't use it at all.
Buffalo, New YorkAges 21–99 - NCT06513819RecruitingPhase 1
HIV and Alcohol Study for People on Multiple Medications
This study looks at how alcohol use affects people with HIV who take multiple medications, including certain brain or nerve drugs. It aims to find safer ways to manage their health.
West Haven, ConnecticutAges 50 years+ - NCT06784908Recruiting
Stress and pain study for people living with HIV
This study looks at how stress affects pain in people with HIV. It may help find better ways to manage pain in this group.
New Haven, ConnecticutAges 18–68 - NCT07225777RecruitingPhase 2
THC's effects on brain and behavior by sex
This study looks at how THC affects men and women differently, focusing on brain activity and behavior. It may help understand why some people react differently to cannabis.
Charleston, South CarolinaAges 21–45 - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy study
This study looks at alcohol and cannabis use among pregnant women in Slovenia by testing newborn meconium (first stool) and asking mothers questions after birth.
LjubljanaAges Any age - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07160153Recruiting
Cannabis Abstinence and Brain Function in Teens
This trial looks at how cannabis affects brain function in teens aged 15–18 who have cannabis use problems. You'll have two neuropsychological tests (like thinking and memory tasks) to see if staying off cannabis helps your brain work better.
Pilsen, CzechiaAges 15–18 - NCT05863910Recruiting
Real-world study of medical cannabis use in children
This study looks at how medical cannabis is used for children and teens in everyday life, by collecting information through online questionnaires. It may help doctors and families better understand which uses are common and how people experience them.
Winnipeg, ManitobaAges 3–17 - NCT05985850RecruitingPhase 2
Can cannabis help with opioid addiction treatment?
This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.
Vancouver, British ColumbiaAges 25 years+
Hear when a new Cannabis Use trial opens
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Common questions
- Are there clinical trials for cannabis use?
- Yes. Clin2 currently lists 104 recruiting cannabis use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.