Clinical trials
Cannabis Use clinical trials
Below are recruiting cannabis use clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06446479RecruitingPhase 2
THC's effect on alcohol use and brain reward
This study tests whether THC (the active ingredient in cannabis) can change how much alcohol you drink and how your brain responds to rewards. You will have MRI scans and take THC or a placebo, then drink alcohol in a controlled setting.
Aurora, ColoradoAges 21–40 - NCT07524985Recruiting
Cannabis Use Study: Understanding Effects in Daily Users
This study looks at how cannabis affects people who use it regularly in their daily lives. Researchers will use a smartphone app to track your experiences and better understand cannabis use in the general population.
Montreal, QuebecAges 18 years+ - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy
This study looks at alcohol and cannabis use during pregnancy by asking new mothers about their habits and testing newborn stool samples (meconium). The goal is to understand how common these substances are among pregnant women in Slovenia and how they might affect babies.
LjubljanaAges Any age - NCT06784908Recruiting
Stress and pain study for people living with HIV
This study looks at how stress affects pain in people with HIV. It may help find better ways to manage pain in this group.
New Haven, ConnecticutAges 18–68 - NCT06699251Recruiting
Brief chat with your doctor about alcohol or cannabis for teens
This study tests whether a short, one-time conversation with a primary care provider can help teens who are at risk for alcohol or cannabis use. It's designed for young people ages 12–17 who get care at two specific health systems.
Commerce, CaliforniaAges 12–19 - NCT06513819RecruitingPhase 1
HIV and Alcohol Study for People on Multiple Medications
This study looks at how alcohol use affects people with HIV who take multiple medications, including certain brain or nerve drugs. It aims to find safer ways to manage their health.
West Haven, ConnecticutAges 50 years+ - NCT06037681Recruiting
Study on cannabis use and pain outcomes in Black and white patients with cancer
This study looks at how cannabis affects pain and daily life in Black and white patients with solid tumors. It compares people who use cannabis at least once a week to those who don't use it at all.
Buffalo, New YorkAges 21–99 - NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05465538RecruitingPhase 1/Phase 2
PET imaging study using SV2A in older adults
This early-phase study tests a PET scan tracer called SV2A in adults age 50 and older. It aims to help researchers understand how the tracer works in the brain/body, which could support future diagnostic or treatment research.
New Haven, ConnecticutAges 50 years+ - NCT05119244Recruiting
Study of environment factors in lung cancer
This study looks at how environmental factors may relate to lung cancer in adults. If you are between 18 and 59 and were treated for primary lung cancer at a participating hospital, you may be able to join.
Le Plessis-RobinsonAges 18–59 - NCT04883255RecruitingEarly Phase 1
Study cannabis effects on brain function in adults with HIV
This early-phase study looks at how cannabis (and the body’s cannabinoid system) may affect thinking and brain-related measures in people with HIV. You may be asked to avoid cannabis and complete several brain and health assessments to see how these factors relate.
San Diego, CaliforniaAges 18–65 - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07160153Recruiting
Cannabis Abstinence and Brain Function in Teens
This trial looks at how cannabis affects brain function in teens aged 15–18 who have cannabis use problems. You'll have two neuropsychological tests (like thinking and memory tasks) to see if staying off cannabis helps your brain work better.
Pilsen, CzechiaAges 15–18 - NCT05863910Recruiting
Real-world study of medical cannabis use in children
This study looks at how medical cannabis is used for children and teens in everyday life, by collecting information through online questionnaires. It may help doctors and families better understand which uses are common and how people experience them.
Winnipeg, ManitobaAges 3–17 - NCT05985850RecruitingPhase 2
Can cannabis help with opioid addiction treatment?
This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.
Vancouver, British ColumbiaAges 25 years+ - NCT07439471Recruiting
Study on tobacco and cannabis co-use in young adults
This study looks at why and how young adults use both tobacco and cannabis together. It may help understand patterns of use and improve future health programs.
Buffalo, New YorkAges 18–30 - NCT07167225Recruiting
Chemical exposure in young adults who use e-cigarettes and cannabis
This study looks at how young adults who use e-cigarettes, cannabis, or both are exposed to harmful chemicals. It aims to understand the health effects of using these products together.
Buffalo, New YorkAges 18–25 - NCT07398443Recruiting
Study of marijuana and tobacco use in young adults
This study looks at how young adults use both marijuana and tobacco, and aims to understand their behaviors. It involves tasks and questionnaires, and may help develop better support for people who use both substances.
Providence, Rhode IslandAges 18–25 - NCT07339150Recruiting
App to reduce alcohol and marijuana use in college students
This trial tests a mobile app designed to help college students reduce their drinking and marijuana use. If you're a student who has had alcohol in the last 90 days, this may be a way to get support.
Charlotte, North CarolinaAges 18–26 - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT04810858Recruiting
Study how chronic marijuana affects brain inflammation in HIV
This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.
Winston-Salem, North CarolinaAges 25–59 - NCT06736444Recruiting
Sleep and Substance Use Help for Young Adults
This study tests a brief program to help young adults who struggle with sleep and also use alcohol or cannabis. The program teaches skills to improve sleep quality and reduce risky substance use.
Seattle, WashingtonAges 18–29 - NCT06084520Recruiting
Pain questionnaire study for opioid and non-opioid patients
This study tests two questionnaires for people with long-term pain. Researchers want to see if the tools work well for both those taking opioids and those who are not. Your answers can help improve pain care.
Uppsala, UpplandAges 18–75
Hear when a new Cannabis Use trial opens
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Common questions
- Are there clinical trials for cannabis use?
- Yes. Clin2 currently lists 96 recruiting cannabis use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.