Clinical trials
Cardiotoxicity clinical trials
Below are recruiting cardiotoxicity clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age - NCT05921253RecruitingEarly Phase 1
Check a brain-heart device to reduce chemo heart risk
This early-phase study tests a “neuromodulation” device (stimulating nerves that may affect the heart and blood vessels) to help lower cardiovascular risks after certain cancer chemotherapy. It may be most relevant if you recently had an anthracycline-based treatment and also have other heart-risk factors.
Oklahoma City, OklahomaAges 18–99 - NCT05921279Recruiting
Study heart events in people with breast cancer
This study looks at what heart-related side effects happen in women with breast cancer who are planned to receive chemotherapy. It may help doctors better understand and monitor these risks during treatment.
GalwayAges 18–90 - NCT06023576RecruitingPhase 2
Blood pressure control during breast cancer chemo
This study tests whether careful blood pressure management can help protect the heart during certain types of chemotherapy (anthracyclines) for breast cancer. Participants will use a smart blood pressure device and may also do an exercise test.
Basking Ridge, New JerseyAges 18 years+ - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT06270667Recruiting
Exercise training for lymphoma survivors
This study tests whether a supervised exercise program can improve heart health in people who finished treatment for Hodgkin or aggressive non-Hodgkin lymphoma 2–5 years ago. The goal is to see if regular exercise helps your heart recover better after chemotherapy or chest radiation.
OsloAges 20–70 - NCT06282796Recruiting
Early heart risk monitoring for breast cancer chemo
This study tests a method to predict and warn about heart damage from a common type of breast cancer chemotherapy. If you have HER2-positive breast cancer and will receive anthracycline drugs, this trial may help monitor your heart health.
Fuzhou, FujianAges 18–80 - NCT06310330Recruiting
Heart monitoring study for breast cancer patients
This study uses heart ultrasound (echocardiogram) to find early signs of heart damage from breast cancer treatment. It aims to better protect your heart during and after therapy.
TrondheimAges 18 years+ - NCT06427226RecruitingPhase 2
Testing dapagliflozin to protect the heart during breast cancer chemo
This trial tests whether a daily pill called dapagliflozin can help protect the heart from damage caused by doxorubicin chemotherapy in people being treated for early-stage breast cancer. If you are starting doxorubicin and have a healthy heart, this might lower your risk of heart problems later.
Alexandria, Bab SharqiAges 18–65 - NCT06443645Recruiting
Protecting the heart during breast cancer treatment
This trial tests whether a diabetes medicine (SGLT2 inhibitor) can prevent heart damage caused by a common chemotherapy drug (anthracycline) in people with early-stage breast cancer. If you are newly diagnosed and about to start chemotherapy or have surgery, this study may be for you.
StrasbourgAges 18 years+ - NCT06491680RecruitingPhase 4
Heart safety during breast cancer chemo
This trial checks how well the heart handles anthracycline chemotherapy in breast cancer patients. It helps doctors find early signs of heart side effects so they can keep you safe during treatment.
Cairo, Cairo GovernorateAges 18–60 - NCT06549621Recruiting
Heart effects of carbon monoxide in hyperbaric oxygen patients
This trial looks at how carbon monoxide poisoning affects the heart in patients who received hyperbaric oxygen therapy. It aims to understand the heart risks after treatment.
BrestAges 18–100 - NCT06595147Recruiting
Exercise for heart health in breast cancer survivors
This study tests if a 12-week exercise program improves heart health in women over 60 who have finished treatment for early-stage breast cancer. You will be placed in either an aerobic exercise group or a stretching group to see which helps your heart more.
Edmonton, AlbertaAges 60 years+ - NCT06664528Recruiting
Heart health study for adults getting certain chemo
This study tracks the heart health of adults receiving chemotherapy that may affect the heart. It helps doctors understand how to better monitor and protect patients.
Rome, LazioAges 18 years+ - NCT06699056Recruiting
AI heart monitor study for ejection fraction
This study uses an AI-powered wearable monitor to check how well your heart pumps blood (ejection fraction) from a simple EKG recording. It may help doctors quickly assess heart function without extra tests.
Orange, CaliforniaAges 18 years+ - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT06774326Recruiting
Spectral CT to check for heart damage from lymphoma treatment
This study uses a special type of CT scan called spectral CT to see if chemotherapy drugs called anthracyclines can cause heart damage in people with certain lymphomas. The goal is to catch any heart problems early by imaging the heart before, during, and after treatment.
BolognaAges 18 years+ - NCT06930521Recruiting
Monitoring heart health during HER2 therapy for breast cancer
This study tracks how well the heart handles HER2-targeted therapy (like Herceptin) during the first year of treatment for early-stage breast cancer. It helps keep you safe by checking heart function closely.
Toronto, OntarioAges 18–79 - NCT07058454Recruiting
Heart safety study for targeted cancer therapies
This study looks at how targeted cancer treatments affect the heart. If you are an adult with any type of cancer and are getting or will get chemotherapy (including targeted drugs), joining this study helps doctors understand heart risks better.
Guangzhou, GuangdongAges 18 years+ - NCT07070765Recruiting
Study on dapagliflozin to protect the heart during breast cancer chemo
This trial tests if a heart-protecting drug called dapagliflozin can help prevent heart damage in breast cancer patients receiving a type of chemotherapy called anthracycline. It may be an option if you have low to medium heart risk factors.
Aberdeen, AberdeenshireAges 18–70 - NCT07233499RecruitingPhase 2
Nebivolol for heart protection during breast cancer treatment
This trial tests if the drug nebivolol can protect the heart from damage caused by trastuzumab (Herceptin) in women with HER2-positive breast cancer. If effective, it may help prevent heart problems while still allowing cancer treatment.
CairoAges 18–65 - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT07382141Recruiting
Heart Health Monitoring During Childhood Cancer Treatment
This study looks at how chemotherapy and other cancer treatments affect the heart in children. It aims to find heart problems early so they can be treated quickly.
Bologna, BolognaAges birth–18 years - NCT01173341Enrolling by invitation
Checking heart side effects of breast cancer treatments
This study looks at how breast cancer medicines affect the heart. It may help doctors better prevent, spot early, and manage heart side effects from trastuzumab and/or anthracycline chemotherapy.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for cardiotoxicity?
- Yes. Clin2 currently lists 53 recruiting cardiotoxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiotoxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiotoxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.