Clinical trials
Cardiotoxicity clinical trials
Below are recruiting cardiotoxicity clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07528586Recruiting
Heart Imaging Study During Cancer Drug Treatment
This study uses heart imaging scans and blood tests to check if a common cancer drug (anthracycline) is affecting your heart during treatment. Early detection might help doctors protect your heart health.
StuttgartAges 18 years+ - NCT07761910RecruitingPhase 2
Study of heart effects of radiation therapy using PET-CT for stage III lung cancer
This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.
Indianapolis, IndianaAges 18 years+ - NCT04262830Recruiting
Heart scans to predict future heart failure after chemotherapy
This trial uses detailed heart imaging (a special MRI scan) to see how chemotherapy may have affected your heart and to predict who could develop heart failure later. If you qualify, it may help your care team better monitor your heart health over time.
San Diego, CaliforniaAges 13–39 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT06132984Recruiting
Heart MRI monitoring for immunotherapy-related heart issues
This study uses heart MRIs to monitor women with gynecologic cancers who are about to start immunotherapy. The goal is to detect early signs of heart problems so doctors can take action quickly.
Chengdu, SichuanAges 18–75 - NCT06340516Recruiting
Looking at a blood test to track heart health during HER2 breast cancer treatment
This trial is checking if a simple blood test (NT-proBNP) can help spot early signs of heart side effects from certain breast cancer treatments (chemotherapy plus HER2 blockers). If successful, it might help doctors adjust treatment sooner to protect your heart.
GothenburgAges 18 years+ - NCT06622954Recruiting
Can a special diet protect the heart during breast cancer treatment?
This trial tests if a special diet can help prevent heart problems caused by chemotherapy in women with triple negative breast cancer. If you're starting a specific type of chemo, you may be able to join.
Rotterdam, South HollandAges 18–75 - NCT06853951RecruitingPhase 3
Protecting hearts during chemotherapy in children
This trial tests whether a medication can prevent heart damage in children and teens receiving chemotherapy. It is for patients aged 2 to 18 who can take oral medication.
CairoAges 1–18 - NCT07137793RecruitingPhase 2
Pentoxifylline to protect the heart during breast cancer chemo
This trial tests if a medicine called pentoxifylline can help prevent heart damage caused by doxorubicin, a common chemotherapy drug for breast cancer. If you are starting doxorubicin for the first time, this study may offer added heart protection.
DamanhūrAges 18–60 - NCT07191730Recruiting
Heart risk prediction for cancer patients on certain chemotherapies
This trial uses a special scoring system (ML Score) to predict if you might develop heart problems while receiving anthracycline chemotherapy or HER2-targeted therapies. It helps doctors decide on the best heart monitoring plan before starting treatment.
CaenAges 18 years+ - NCT07663357Recruiting
Blood test to detect heart damage from breast cancer treatment
This study looks at whether a simple blood test can spot early signs of heart damage from certain breast cancer treatments (anthracycline chemo or anti-HER2 drugs). The goal is to protect your heart while you get the cancer treatment you need.
Fortaleza, CearáAges 18 years+ - NCT05256745RecruitingPhase 1/Phase 2
A medicine to protect the heart during breast cancer chemotherapy
This early-phase study tests azeliragon to lower the risk of chemotherapy-related heart damage in women with early-stage breast cancer. Participants get their planned standard chemotherapy, plus the study medicine, and are monitored for safety and heart health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04260269Enrolling by invitation
Testing a switch to a different chemotherapy type after heart side effects
This study looks at whether people with solid tumors who develop heart-related side effects during a fluoropyrimidine chemotherapy can safely switch to a different fluoropyrimidine. It aims to see if the new option is feasible to use again when the first one caused cardiotoxicity.
OdenseAges 18 years+ - NCT06353191Recruiting
Blood markers to predict heart problems from cancer therapy
This study looks for early warning signs (biomarkers) of heart damage caused by cancer treatments. It is for people who have had cancer treatment, may have heart issues, or are about to start a treatment that could affect the heart.
Scottsdale, ArizonaAges 18 years+ - NCT07654426RecruitingPhase 2
Heart protection during lymphoma chemotherapy
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
Boston, MassachusettsAges 18 years+ - NCT03418961RecruitingPhase 3
Study of heart-risk management for metastatic HER2 breast cancer
This trial follows people with metastatic HER2-positive breast cancer who are at higher risk for heart damage while on HER2-targeted therapy. Some participants are randomly assigned to different monitoring/heart-protection approaches to see what best helps keep the heart safe.
Anchorage, AlaskaAges 18 years+ - NCT03711110Recruiting
Heart-protection plan for older people with certain cancers
This trial looks at strategies to help prevent heart and blood-vessel problems in people over 65 who have certain cancers. It may help by monitoring and treating heart risks early to lower the chance of future cardiovascular events.
Santiago de Compostela, A CoruñaAges 65 years+ - NCT04822077Recruiting
Proton beam treatment for thymus tumors
This trial studies proton radiotherapy (a type of radiation) for cancers of the thymus, like thymoma or thymic carcinoma. It may help improve tumor control while limiting radiation exposure to nearby organs.
Umeå, NorrlandAges 18 years+ - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT05406635Recruiting
Imaging vs blood tests to guide heart-safe HER2 treatment
This trial compares whether special heart imaging or blood tests better helps monitor heart safety while you receive HER2-targeted therapy (like trastuzumab, with or without pertuzumab) plus chemotherapy. It may help doctors catch early heart stress and choose the safest treatment plan for you.
AalborgAges 18–90 - NCT05598879Recruiting
New heart-cancer visit registry for adults
This study is a “registry,” meaning it collects health information from adults who are getting a new heart (cardio) evaluation related to cancer. It helps doctors better understand heart risks and care needs for different cancer types and treatments.
Weston, FloridaAges 18 years+ - NCT05703126Recruiting
Blood vessel and heart strength tests in AML patients
This study looks at how well your blood vessels and heart pumping ability work in people with acute myeloid leukemia (AML) receiving certain chemotherapy. It may help doctors better understand heart risk during treatment and tailor monitoring to you.
Samara, Samara OblastAges 18–65 - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05769868RecruitingPhase 3
Esmolol test to spot heart problems in diabetes, cirrhosis, and cancer
This trial tests whether esmolol (a short-acting heart medicine) can help doctors identify certain heart-related problems in people with type 2 diabetes, liver scarring (cirrhosis), or specific cancers. It’s mainly about improving how heart issues are detected during ultrasound testing.
Barcelona, BarcelonaAges 18 years+
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Cardiotoxicity trials by city
Studies with a site in or near these metro areas.
Cardiotoxicity trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cardiotoxicity?
- Yes. Clin2 currently lists 53 recruiting cardiotoxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiotoxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiotoxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.