Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06801561Recruiting
Sealants and Laser to Prevent Cavities in MIH-Affected Molars
This trial tests whether a dental sealant or a special laser treatment can prevent cavities and breakdown in first permanent molars affected by MIH (a condition that makes enamel weak). Eligible children have a molar with MIH that hasn't yet broken down and has only minor cavities.
AlexandriaAges 6–9 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT06991842Recruiting
Etching time for front tooth fillings
This study looks at how long to etch the tooth before placing a white filling on a front tooth. You may qualify if you need a standard filling on the side or corner of a front tooth.
Basel, Canton of Basel-CityAges 18 years+ - NCT07009015Recruiting
Oral health program for children
This study tests whether an oral health program helps improve children's knowledge and habits. It is for boys aged 10 to 11 who have their parent's permission.
Serdang, SelangorAges 10–11 - NCT07031856Recruiting
3D printed vs. CAD-CAM dental restorations comparison
This trial compares two modern ways to make partial dental restorations (like crowns or bridges): one using a 3D printer and the other using a computer-aided design and manufacturing (CAD-CAM) system. It aims to see which method works better for people who need a couple of teeth fixed.
Adana, SarıçamAges 18–65 - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07123025Recruiting
Partial pulp treatment for painful tooth decay
This study tests if removing only the top part of the damaged tooth nerve can save a deeply decayed molar. It is for people with moderate to severe toothache that doesn't stop, especially when lying down.
Rohtak, HaryanaAges 15–40 - NCT07133919Recruiting
AI communication to reduce dental anxiety in children
This trial tests whether a child-friendly, AI-assisted conversation method can help reduce anxiety in children who need a dental filling, pulpotomy, or similar treatment. It is for children ages 6-12 who are coming to the dentist for the first time and will receive local anesthesia.
Çanakkale, KepezAges 7–12 - NCT07134114Recruiting
How Hall Crowns Affect Your Child's Bite
This study tests the Hall Technique, a way to place stainless steel crowns on baby molars without numbing or drilling. It looks at how the crown affects your child's bite, and may help kids with cavities in back baby teeth who can cooperate for treatment.
Ankara, KeçiörenAges 7–10 - NCT07181967Recruiting
SDF vs fluoride varnish for cavity bacteria in kids
This study compares a silver-containing liquid (SDF) to a fluoride varnish to see which works better at reducing cavity-causing bacteria in children's mouths. It may help your child if they have cavities in their baby teeth.
Asyut, Asyut GovernorateAges 3–8 - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT07212660Recruiting
Comparing two curing methods for fillings in baby teeth
This trial tests two different ways of hardening (curing) the material used for fillings in baby molars. It aims to see which method works better and is safer for children needing fillings for cavities or other damage.
Herzogenbuchsee, Canton of BernAges 4–9 - NCT07244991Recruiting
Effect of a special toothpaste on plaque bacteria and cavities during braces treatment
This trial tests whether a special paste (MI Paste Plus) can reduce cavity-causing bacteria and prevent early white spots on teeth while you are wearing braces.
Tirana, AlbaniaAges 5–45 - NCT07302581Recruiting
Study of dental implants with natural ligament for single tooth replacement
This trial tests a new type of dental implant that includes a ligament (like a natural tooth's shock absorber). It's for people who need to have a single front or side tooth pulled and have healthy gum and bone around the area. The goal is to see if this implant works well and stays healthy over time.
Kōriyama, FukushimaAges 18 years+ - NCT07323433Recruiting
Chitosan dressing for pulp treatment in immature teeth
This trial tests a special chitosan dressing used during a partial root canal treatment (pulpotomy) for immature permanent front teeth. It may help the tooth continue to develop and heal without the need for more complex procedures.
MinyaAges 7–15 - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT07547904Recruiting
Bioactive filling material for back tooth cavities
This trial tests a newer type of tooth-filling material (bioactive bulk-fill) in back teeth that need repair. Researchers will compare how well it works compared to standard fillings, which may help improve how long fillings last.
IstanbulAges 18–50 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT07619729Enrolling by invitationPhase 4
Oral Health Program for People With Type 2 Diabetes
This study tests whether a text-message and online program about caring for your teeth and gums can help people with type 2 diabetes. Researchers want to see if better oral health habits improve overall health outcomes.
Long Island City, New YorkAges 18 years+ - NCT07324928Enrolling by invitation
Pulpotomy treatment for baby teeth using iron sulfate or MTA
This study compares two materials (iron sulfate and a special cement called MTA) used during a pulpotomy—a procedure to treat cavities in baby molars when the nerve is exposed. It aims to find which material works better to keep the tooth healthy until it falls out naturally.
Jizan, Jazan RegionAges 6–10 - NCT07011381Enrolling by invitation
Parent views on children's oral health: refugees vs Egyptians
This study looks at how parents view their child's oral health (teeth and mouth) and how it affects daily life. It compares views of Sudanese refugee parents and Egyptian parents living in Cairo.
Kafr ash Shaykh, Kafr Ash Shaikh/ ElhamrawyAges 6–12 - NCT06863103Enrolling by invitation
Treating children with major dental needs
This study explores how dentists and dental specialists treat children who need a lot of dental work. It aims to improve care for kids with extensive dental needs.
MalmöAges Up to 65 years - NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 122 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.