Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07716254Recruiting
Dental cavity risk quiz study for Egyptian adults
This study tests a new questionnaire to see how well it can predict your risk of cavities. You will answer questions about your teeth and habits, and your answers will be compared with a dentist's exam.
Giza, Sixth of OctoberAges 18–65 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07330570Recruiting
Caries risk after dental surgery under general anesthesia
This study looks at how likely children are to get new cavities after they have had dental treatment under general anesthesia for early childhood cavities. It aims to help dentists better understand and prevent future decay.
Aydin, AydınAges 6–16 - NCT07142629Enrolling by invitation
Cavity removal methods for MIH-affected molars
This trial compares two ways of removing tooth decay in children with a condition called MIH (which makes enamel weak and spotted). It tests whether selective or non-selective drilling works better for deep cavities, aiming to save the tooth and keep the nerve healthy.
IrbidAges 6–13 - NCT07041905Recruiting
Comparing two ways to treat deep cavities in back teeth
This study compares two ways of removing deep tooth decay to see which keeps the tooth nerve healthy and causes less pain afterward. It's for people who have two deep cavities on opposite sides of their mouth and want to help find the best treatment.
AdanaAges 15–55 - NCT07859553Recruiting
Powered or manual toothbrushes for cavity risk in pre-teens
This study compares using a powered (electric) toothbrush versus a manual toothbrush in children aged 8 to 12 to see which is better at reducing the risk of cavities. Your child must already have some signs of tooth decay or a history of cavities in the past few years.
Ann Arbor, MichiganAges 8–12 - NCT06558955Recruiting
Preventing baby tooth decay with text support for new moms
This study tests a program that uses text messages and online support to help new moms prevent cavities in their baby's teeth. It provides tips and support from other parents to make dental care easier for your little one.
SingaporeAges 21 years+ - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07680868Recruiting
Caris Chromoseq data collection for blood cancers
This study collects data from a special genetic test called Caris Chromoseq for people with certain blood cancers. It aims to learn more about these diseases and possibly guide better treatments.
Phoenix, ArizonaAges 18 years+ - NCT07671651Recruiting
Ozone therapy for early tooth decay in children
This trial tests whether ozone therapy can help reverse the earliest stages of tooth decay (white spots on teeth) in children. Children aged 6–12 with small, non-cavity spots may benefit from this treatment instead of traditional fillings.
Istanbul, MaltepeAges 6–14 - NCT07609797Recruiting
Fluoride and Mouthwash Effects on Cavity Markers in Children
This study tests whether sodium fluoride and chlorhexidine (a prescription mouthwash) change certain markers in saliva that may relate to tooth decay in children with cavities. The goal is to understand if these common dental treatments affect the body's natural cavity-fighting substances.
Alanya, AntalyaAges 6–8 - NCT07560514Recruiting
Testing New Digital Tools to Detect Tooth Decay
This study tests new digital technologies—including a special camera called DIAGNOcam and AI software—to detect tooth decay early and accurately. If you have some cavities and healthy teeth in specific areas of your mouth, you may be eligible to help researchers improve how dentists find and diagnose tooth decay.
Martin, Žilina RegionAges 18–65 - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT07250022Recruiting
Checking for hidden decay after tooth fillings in children
This study tests a gentle way to fill cavities in baby teeth (called Atraumatic Restorative Treatment, or ART) to see if some decay is left behind. It may be a good option for children with cavities who are nervous about traditional dental drills.
Çanakkale, KepezAges 4–9 - NCT06736964Enrolling by invitation
Testing new fillings for gum-line cavities in high-risk adults
This study tests how well two newer, tooth-friendly filling materials work for cavities at the gum line in people who are prone to tooth decay. If you need a couple of these fillings, this trial could help restore your teeth and protect them from future cavities.
CairoAges 25–45 - NCT06152081Recruiting
Detecting cavities with two new devices
This study tests two different devices for finding cavities in adults at high risk for tooth decay, comparing how well they work against each other and standard methods.
Boston, MassachusettsAges 21 years+ - NCT03969628Recruiting
Testing two ways to check tooth-caries risk in children
This study compares two different methods of estimating how likely a child is to get tooth decay. If you visit the children’s dental clinic, the researchers will use these methods to help identify risk and plan prevention.
Pelotas, Rio Grande do SulAges 7–11 - NCT07869407Recruiting
Painless cavity filling: new tools vs traditional drill
This trial compares two newer methods for removing tooth decay (smart burs and a dissolving gel called Carisolv) to the traditional drill, to see which causes less pain during the procedure. It may help find a more comfortable way to treat cavities.
Peshawar, Khyber PakhtunkhwaAges 18–45 - NCT07825415Recruiting
Understanding pulpitis severity to improve tooth-saving treatment
This study looks at whether markers of inflammation in the dental pulp (the nerve and blood vessels inside the tooth) can predict how well a tooth-saving procedure called full pulpotomy works for molars with very deep cavities. If successful, this could help doctors choose the best treatment for severe tooth pain.
Rohtak, HaryanaAges 18–40 - NCT07732127Recruiting
Finding early cavities with fluorescent starch nanoparticles
This trial tests a new way to spot very early cavities using fluorescent starch nanoparticles, and compares it to saliva tests. It might help detect tooth decay before it needs a filling.
Shibīn al Kawm, MenoufiaAges 18–40 - NCT07711132Recruiting
Remineralizing toothpaste for early cavities in teens
This trial tests three different treatments for repairing very early cavities on tooth enamel: a nano-eggshell paste, a special milk protein paste (CPP-ACP), and a standard fluoride paste. It is for teenagers and young adults who have a few small spots of early decay and a moderate to high risk of getting cavities.
Al MansurahAges 15–20 - NCT07648212Recruiting
AI Tool for Detecting Tooth Decay in Dental Training
This study tests whether artificial intelligence can help dental students and residents better detect early tooth decay (cavities) between teeth. Participants will learn to use an AI tool and compare it to traditional detection methods to see if it improves accuracy.
Ann Arbor, MichiganAges 18–99 - NCT07611981Recruiting
Tooth Decay and Oral Health in Children With Learning Disabilities
This study compares tooth decay and brushing habits between children with specific learning disabilities and healthy children. Researchers want to understand if children with learning disabilities need special dental care strategies.
Alanya, AntalyaAges 7–12 - NCT06514885Recruiting
Silver diamine fluoride for root cavities in older adults
This trial studies a special liquid called silver diamine fluoride that is painted onto cavities on tooth roots. It may help stop the decay and keep the tooth healthy without drilling.
Hong KongAges 60 years+
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 112 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.