Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07330570Recruiting
Caries risk after dental surgery under general anesthesia
This study looks at how likely children are to get new cavities after they have had dental treatment under general anesthesia for early childhood cavities. It aims to help dentists better understand and prevent future decay.
Aydin, AydınAges 6–16 - NCT07716254Recruiting
Dental cavity risk quiz study for Egyptian adults
This study tests a new questionnaire to see how well it can predict your risk of cavities. You will answer questions about your teeth and habits, and your answers will be compared with a dentist's exam.
Giza, Sixth of OctoberAges 18–65 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07041905Recruiting
Comparing two ways to treat deep cavities in back teeth
This study compares two ways of removing deep tooth decay to see which keeps the tooth nerve healthy and causes less pain afterward. It's for people who have two deep cavities on opposite sides of their mouth and want to help find the best treatment.
AdanaAges 15–55 - NCT07142629Enrolling by invitation
Cavity removal methods for MIH-affected molars
This trial compares two ways of removing tooth decay in children with a condition called MIH (which makes enamel weak and spotted). It tests whether selective or non-selective drilling works better for deep cavities, aiming to save the tooth and keep the nerve healthy.
IrbidAges 6–13 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07250022Recruiting
Checking for hidden decay after tooth fillings in children
This study tests a gentle way to fill cavities in baby teeth (called Atraumatic Restorative Treatment, or ART) to see if some decay is left behind. It may be a good option for children with cavities who are nervous about traditional dental drills.
Çanakkale, KepezAges 4–9 - NCT06736964Enrolling by invitation
Testing new fillings for gum-line cavities in high-risk adults
This study tests how well two newer, tooth-friendly filling materials work for cavities at the gum line in people who are prone to tooth decay. If you need a couple of these fillings, this trial could help restore your teeth and protect them from future cavities.
CairoAges 25–45 - NCT06152081Recruiting
Detecting cavities with two new devices
This study tests two different devices for finding cavities in adults at high risk for tooth decay, comparing how well they work against each other and standard methods.
Boston, MassachusettsAges 21 years+ - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT06365281Recruiting
Cavity risk study for adults 35–44 years old
This study looks at how common cavities are and what factors might increase the risk of them in people ages 35–44. By joining, you'll help researchers learn more about oral health in this age group among Egyptians.
GizaAges 35–44 - NCT06558955Recruiting
Preventing baby tooth decay with text support for new moms
This study tests a program that uses text messages and online support to help new moms prevent cavities in their baby's teeth. It provides tips and support from other parents to make dental care easier for your little one.
SingaporeAges 21 years+ - NCT07680868Recruiting
Caris Chromoseq data collection for blood cancers
This study collects data from a special genetic test called Caris Chromoseq for people with certain blood cancers. It aims to learn more about these diseases and possibly guide better treatments.
Phoenix, ArizonaAges 18 years+ - NCT07671651Recruiting
Ozone therapy for early tooth decay in children
This trial tests whether ozone therapy can help reverse the earliest stages of tooth decay (white spots on teeth) in children. Children aged 6–12 with small, non-cavity spots may benefit from this treatment instead of traditional fillings.
Istanbul, MaltepeAges 6–14 - NCT07560514Recruiting
Testing New Digital Tools to Detect Tooth Decay
This study tests new digital technologies—including a special camera called DIAGNOcam and AI software—to detect tooth decay early and accurately. If you have some cavities and healthy teeth in specific areas of your mouth, you may be eligible to help researchers improve how dentists find and diagnose tooth decay.
Martin, Žilina RegionAges 18–65 - NCT07609797Recruiting
Fluoride and Mouthwash Effects on Cavity Markers in Children
This study tests whether sodium fluoride and chlorhexidine (a prescription mouthwash) change certain markers in saliva that may relate to tooth decay in children with cavities. The goal is to understand if these common dental treatments affect the body's natural cavity-fighting substances.
Alanya, AntalyaAges 6–8 - NCT07648212Recruiting
AI Tool for Detecting Tooth Decay in Dental Training
This study tests whether artificial intelligence can help dental students and residents better detect early tooth decay (cavities) between teeth. Participants will learn to use an AI tool and compare it to traditional detection methods to see if it improves accuracy.
Ann Arbor, MichiganAges 18–99 - NCT07186673Recruiting
Comparing two types of crowns for back teeth in children
This study compares two ways to fix cavities in children's permanent back molars: a special 'Hall' crown that is placed without numbing or drilling, versus a traditional crown. It aims to see which one works better and is more comfortable for kids.
LatakiaAges 8–15 - NCT06944028Enrolling by invitation
Stepwise cavity treatment for deep decay in young teeth
This trial tests a gentler way to remove deep cavities in young permanent molars or premolars, aiming to save more of the tooth and protect the nerve. It may be an option for children and teens with deep decay that hasn't reached the pulp.
StockholmAges 8–19 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT07732127Recruiting
Finding early cavities with fluorescent starch nanoparticles
This trial tests a new way to spot very early cavities using fluorescent starch nanoparticles, and compares it to saliva tests. It might help detect tooth decay before it needs a filling.
Shibīn al Kawm, MenoufiaAges 18–40 - NCT07711132Recruiting
Remineralizing toothpaste for early cavities in teens
This trial tests three different treatments for repairing very early cavities on tooth enamel: a nano-eggshell paste, a special milk protein paste (CPP-ACP), and a standard fluoride paste. It is for teenagers and young adults who have a few small spots of early decay and a moderate to high risk of getting cavities.
Al MansurahAges 15–20 - NCT07578662Recruiting
Direct Pulp Capping for Deep Cavities in Back Teeth
This study tests a treatment where dentists cap (seal) an exposed tooth nerve in deep cavities of back teeth to see if it heals properly. This might help save your tooth instead of needing a root canal.
Rohtak, HaryanaAges 15–40 - NCT05758454Recruiting
Prevent tooth decay and childhood weight gain by helping new parents
This study supports parents of babies (0–6 months) to change certain health habits with the goal of reducing future tooth decay and supporting healthy weight as children grow. You may be able to join if you recently had a newborn and you’re comfortable with the study procedures.
BergenAges 20–50
Hear when a new Caries trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 124 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.