Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT06863103Enrolling by invitation
Treating children with major dental needs
This study explores how dentists and dental specialists treat children who need a lot of dental work. It aims to improve care for kids with extensive dental needs.
MalmöAges Up to 65 years - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70 - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT06714929Recruiting
School water study for students in grades K-5
This study looks at how a new water program in schools might affect student health and hydration. It includes watching what kids drink at lunch, checking teeth and body weight for older students, and asking 4th and 5th graders and staff about their drinks.
Henrico, VirginiaAges 4 years+ - NCT06706115Recruiting
Testing breast milk nasal drops in preterm babies
This study tests whether putting a few drops of breast milk into a preterm baby's nose can help their brain get more oxygen. It is for babies who are not yet ready to feed all by mouth and who don't have certain health problems.
KonyaAges 6 months–9 months - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT06699199RecruitingPhase 4
Testing silver diamine fluoride on mouth bacteria in kids
This study tests if a liquid medicine (silver diamine fluoride) painted on baby teeth cavities can change the bacteria in a child's mouth. It is for healthy children ages 4–10 with an open cavity.
Jeddah, Mecca RegionAges 4–12 - NCT06683833RecruitingPhase 4
Comparing materials for protecting tooth nerves in deep cavities
This study compares three materials used to protect the nerve inside a deep cavity. If you have a deep cavity in a live tooth, you may be able to join and help find which material works best.
CairoAges 22–45 - NCT06685640Recruiting
Comparing metal and ceramic crowns for back baby teeth
This trial tests whether stainless steel or zirconia crowns work better for fixing cavities in children's back baby teeth after nerve treatment. It can help parents choose the best option for their child.
Aydin, AydınAges 4–5 - NCT06677983Recruiting
How well do Bioflx crowns work for children's back baby teeth?
This study tests how well children and parents like a new type of crown for baby molars. The crowns are placed on back baby teeth that need full coverage, and the study looks at how they perform and how comfortable and satisfied you and your child are.
AlexandriaAges 4–8 - NCT06645860Recruiting
Smart treatment for painless cavities in baby teeth
This study tests a special treatment (SMART) for cavities in baby teeth that don’t hurt. It uses different materials to fix the holes, and may help avoid more complex procedures.
Çanakkale, KepezAges 4–9 - NCT06641011Recruiting
Sealing molars with enamel spots: rinsing vs blotting
This study tests whether rinsing off or blotting dry a special silver fluoride liquid before placing a tooth sealant helps the sealant last longer on molars affected by a common condition called molar-incisor hypomineralization. The goal is to find the best way to protect these teeth from cavities.
AnkaraAges 6–14 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT06006429Recruiting
Using a scanner to check teeth and gums
This study tests if a special intraoral scanner can help dentists find gum problems and tooth issues. If you have receding gums, you may be able to join.
ReimsAges 18 years+ - NCT06555029Recruiting
Oral health help for older adults on Medicaid
This trial is testing an oral health program offered during routine primary care visits for older adults (55+) on Medicaid. It aims to see if adding dental care support to regular check-ups can improve health.
Cleveland, OhioAges 55 years+ - NCT06517927Recruiting
Long-term dental effects of childhood cancer chemo
This study looks at how chemotherapy given before age 10 affects teeth later in life. Researchers want to know if childhood cancer survivors have more dental problems than others.
BrusselsAges 12–36 - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT05761197Recruiting
Study of mouth yeast infection and a preventive treatment
This trial studies children ages 9–15 months and looks at oropharyngeal yeast infection in the mouth (often called “OPC”). It may help researchers understand how to prevent or manage this condition.
Philadelphia, PennsylvaniaAges 9 months–1.3 years
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 112 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.