Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,990 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06182657Recruiting
Nasopharyngeal cancer response to induction chemotherapy
This study looks at how well nasopharyngeal cancer (NPC) responds to the first round of chemotherapy before other treatments. It aims to see if the amount of tumor shrinkage can help predict outcomes and guide future care for people with advanced NPC.
Nanchang, JiangxiAges 18 years+ - NCT07173387RecruitingPhase 2
Radiation plus chemo for locally advanced pancreatic cancer
This trial combines focused radiation with a chemotherapy drug combo to help shrink or control locally advanced pancreatic cancer. If it works, this treatment might make the tumor smaller and improve quality of life.
Jinan, ShandongAges 18–75 - NCT07863999RecruitingPhase 3
Immunotherapy before surgery for stage II-III lung cancer
This trial compares two different drug combinations given before surgery for stage II-III non-small cell lung cancer (NSCLC). Both combinations include chemotherapy, and one also includes a newer type of immunotherapy. The goal is to see which approach shrinks tumors more effectively before surgery.
Shanghai, ChinaAges 18 years+ - NCT07855640Recruiting
Immunotherapy plus chemo for advanced stomach cancer with fluid in belly
This trial tests a new combination for advanced stomach cancer that has spread and caused fluid buildup in the belly (malignant ascites). It combines an immunotherapy drug (anti-PD-1) with standard chemotherapy and a targeted chemotherapy given directly into the belly to see if it can shrink the cancer and help you feel better.
Hangzhou, ZhejiangAges 18–75 - NCT05988814RecruitingPhase 2
FOLFIRINOX3 for advanced pancreatic cancer
This trial tests a stronger version of FOLFIRINOX chemotherapy for people with pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body. It aims to see if the new dosing schedule works better and is safe.
DijonAges 18 years+ - NCT06255210RecruitingPhase 2
Chemotherapy before surgery for olfactory neuroblastoma
This trial tests whether giving chemotherapy before surgery can help treat olfactory neuroblastoma, a rare type of nose cancer. It aims to see how safe and effective this approach is for people with early to advanced tumors that have not spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07872722RecruitingPhase 2
Study of two immunotherapies plus chemotherapy before surgery for stomach cancer
This trial tests a new approach for stomach cancer that hasn't spread. You'd get a combination of an investigational drug targeting a specific protein on cancer cells, an immunotherapy that helps your immune system fight cancer, and standard chemotherapy before surgery. The goal is to see if this makes the tumor shrink more and improves outcomes.
SaitamaAges 18 years+ - NCT03326947RecruitingPhase 2
Stathmin test to guide chemotherapy for oral cancer
This Phase 2 trial uses a lab test called “Stathmin” to help predict who may benefit from a specific chemotherapy plan for squamous cell carcinoma of the mouth. It aims to improve treatment choice by linking Stathmin levels to how well chemotherapy works.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05377658RecruitingPhase 2
AK104 with chemo before and after surgery for lung cancer
This trial studies AK104 along with chemotherapy given before surgery and after surgery for people with resectable (operable) stage II to IIIA non-small cell lung cancer. It aims to improve treatment effectiveness by shrinking the tumor before surgery and helping prevent it from coming back afterward.
Zhengzhou, HenanAges 18–75 - NCT06270017RecruitingPhase 1/Phase 2
Zebrafish Avatars for Colon Cancer Treatment
This trial uses tiny zebrafish to grow a piece of your tumor and test which treatments might work best for you. It is for patients with colon cancer who are scheduled for surgery to remove their tumor.
Linköping, Östergötland CountyAges 18 years+ - NCT06271421Recruiting
Nanoparticle heat therapy for recurrent glioblastoma
This trial tests a new treatment for recurrent glioblastoma using tiny magnetic particles (nanoparticles) that are heated to kill cancer cells. The particles are injected into the tumor, and then a magnetic field device heats them up. It's for people who have already tried standard therapy and whose tumor has come back.
PoznanAges 18 years+ - NCT07874308Recruiting
Preventing nausea and vomiting from chemotherapy
This study tests a new anti-nausea drug (HR20013) in patients receiving chemotherapy that often causes nausea and vomiting. It aims to see how well it works in real-world conditions, including for patients with liver problems.
Guangzhou, GuangdongAges 18 years+ - NCT07868861RecruitingPhase 1
Nasal ondansetron versus IV injection in healthy adults
This trial tests a new nasal spray form of ondansetron (a medicine that prevents nausea and vomiting) to see how well the body absorbs it compared with the IV (into the vein) form. It is for healthy adults to help understand how the nasal spray works.
JerusalemAges 18–65 - NCT06281210Recruiting
Test to skip breast surgery after chemo
This trial checks if a breast biopsy can confirm that chemo has destroyed all cancer cells, so you might avoid surgery altogether. It's for people with aggressive breast cancer types who responded well to chemotherapy.
Candiolo, TurinAges 18 years+ - NCT06282796Recruiting
Early heart risk monitoring for breast cancer chemo
This study tests a method to predict and warn about heart damage from a common type of breast cancer chemotherapy. If you have HER2-positive breast cancer and will receive anthracycline drugs, this trial may help monitor your heart health.
Fuzhou, FujianAges 18–80 - NCT06293014RecruitingPhase 2
TAS-102 with bevacizumab for colorectal cancer maintenance
This trial tests a combination of two drugs, TAS-102 and bevacizumab, as a follow-up maintenance treatment for people with advanced colorectal cancer. The goal is to see if this treatment can keep the cancer from growing after initial chemotherapy and bevacizumab therapy.
Zhengzhou, HenanAges 18 years+ - NCT06194734RecruitingPhase 3
KC1036 vs. chemo for advanced esophageal cancer
This study compares a new drug, KC1036, to standard chemotherapy options for people with advanced esophageal squamous cell cancer that has progressed after immunotherapy and at least one chemo. It aims to see if KC1036 works better or has fewer side effects.
BeijingAges 18–75 - NCT06307249RecruitingPhase 1
Precision therapy for solid tumors targeting CDK4/6 and VEGF
This trial tests a combination of two targeted drugs for advanced solid tumors like colorectal, lung, breast, and genitourinary cancers. The goal is to see if blocking certain proteins and a long RNA molecule can slow tumor growth.
Tripoli, North LebanonAges 18 years+ - NCT06308354Recruiting
Colorectal cancer data study at Xijing Hospital
This study collects and reviews medical records from patients diagnosed with colorectal adenocarcinoma at Xijing Hospital between 2013 and 2023. The goal is to build a dataset for future research—no new treatments or procedures are being tested.
Xi'an, ShaanxiAges 18–100 - NCT06304350RecruitingPhase 2
Pembrolizumab plus chemo before surgery for esophageal cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (given before surgery) can help shrink stage II/III esophageal cancer. The goal is to make surgery more likely to remove all cancer and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06037733Recruiting
Focused radiation to main tumor after chemo-immunotherapy for lung cancer
This trial is for people with advanced non-small cell lung cancer whose tumors responded well to initial chemo-immunotherapy. Instead of giving full chest radiation, doctors will only target the main tumor to see if it can prevent regrowth with fewer side effects.
Wuhan, HubeiAges 18–75 - NCT06020430Recruiting
Skipping routine radiation for advanced lung cancer after immunotherapy and chemo
This trial tests whether it is safe to skip routine radiation to the tumor bed in patients with stage III lung cancer that has responded well to immunotherapy and chemotherapy. It aims to reduce side effects while still controlling the cancer.
Wuhan, HubeiAges 18–75 - NCT06227117RecruitingPhase 2
Study of DV and Toripalimab before surgery for HER2-low breast cancer
This trial tests a combination of two drugs (DV and Toripalimab) with chemotherapy before surgery for a specific type of breast cancer (HER2-low, HR-negative) that has not spread too far. The goal is to see if this approach can shrink the tumor and improve outcomes.
Changsha, HunanAges 18 years+ - NCT06313450Recruiting
Lower radiation for nose cancer after immunotherapy and chemo
This trial tests whether giving a lower dose of radiation to the main tumor is safe and effective for people with nasopharyngeal cancer (a type of nose/throat cancer) who first receive a combination of immunotherapy (toripalimab) and chemotherapy. It aims to reduce side effects while still controlling the cancer.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,990 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.