Clinical trials
Chlorhexidine clinical trials
Below are recruiting chlorhexidine clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07191262Recruiting
Comparing mouth rinses after tooth extraction and bone graft
This study compares three different mouth rinses (one with EDTA, one with chlorhexidine, and one with essential oils) after tooth extraction and bone grafting. It aims to find which rinse helps keep the area clean and promotes healing.
Birmingham, AlabamaAges 18–85 - NCT07429812Enrolling by invitation
Chitosan-Chlorhexidine Gel for Healing After Tooth Extraction
This trial tests a gel made from chitosan and chlorhexidine to see if it helps heal wounds faster after tooth removal in people with diabetes.
Al KharjAges 20–50 - NCT07356323Recruiting
Study on antibacterial drape for hip or knee replacement
This trial tests if a special antibacterial drape reduces contamination during hip or knee replacement surgery. The drape is placed over the skin to help prevent infection.
Fishers, IndianaAges 22 years+ - NCT06126614RecruitingPhase 3
Infection prevention in joint replacement surgery
This trial tests a way to prevent infections for people getting a hip or knee replacement. It compares different methods to see which works best and may help lower your risk of infection after surgery.
Hamilton, OntarioAges 18 years+ - NCT06587880RecruitingPhase 4
Mouthwash and wisdom tooth extraction recovery
This study compares different mouthwashes to see which one helps healing after wisdom tooth surgery. If you have a lower wisdom tooth that is impacted (stuck) and need it removed with some bone cutting, you may qualify.
AmmanAges 18 years+ - NCT07555366Recruiting
Healing after tooth extraction: two treatment approaches
This study compares two treatments applied to the socket (the hole left after a tooth is removed) to help it heal better. One treatment uses a product called microRepair, and the other uses chlorhexidine, a common antimicrobial rinse. The goal is to see which helps the extraction site heal faster and with fewer problems.
Roma, RMAges 18–75 - NCT07742826Recruiting
Platelet-rich fibrin vs. steroids after wisdom tooth removal
This study compares two treatments to reduce pain and swelling after removing an impacted wisdom tooth: one uses a special blood clot (platelet-rich fibrin) placed in the socket, and the other uses steroid medication. The goal is to find which works better for healing and comfort.
NicosiaAges 18 years+ - NCT07239219Recruiting
Testing a special rinse to prevent infection after catheter removal
This trial tests whether using a special antiseptic solution (Irrisept) when removing a urinary catheter can lower the chance of getting a urinary tract infection. It is for people visiting a urology clinic for catheter removal who are not already on antibiotics.
Columbus, OhioAges 18 years+ - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Newport Beach, CaliforniaAges 18 years+ - NCT03384537RecruitingEarly Phase 1
Tropolone mouthwash test in healthy adults
This early trial compares a mouthwash that contains tropolone versus a mouthwash without tropolone to see how well each works against germs in the mouth. You may be asked to pause your usual mouth-cleaning routine for a few days beforehand.
CairoAges 18–45 - NCT05679661Recruiting
Immunity-focused nutrition before surgery to reduce lung infections
This study gives an immunity-supporting nutrition plan and an oral cleaning product before and around surgery to help older adults avoid breathing-related complications. It is mainly for people at higher risk of post-surgery lung problems, and it checks whether the approach is safe and helpful.
BeijingAges 65 years+ - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT06045429RecruitingPhase 4
Mouth rinse for ICU patients on breathing machines
This trial tests if using a special mouthwash (3% hydrogen peroxide) can reduce bacteria in the lungs of ICU patients on breathing machines. It may help prevent infections in people who are already very sick.
PragueAges 18 years+ - NCT06163469Recruiting
Chlorhexidine bladder wash for people with long-term suprapubic catheters
This study tests whether washing the bladder with a solution called chlorhexidine (a germ-killer) can lower the number of unplanned hospital visits and improve quality of life for people who have a long-term suprapubic catheter. You may be eligible if you have had a catheter for at least a year and have had a recent urinary tract infection.
New Haven, ConnecticutAges 18 years+ - NCT06339203Recruiting
Saline vs. special antiseptic for c-section wound cleaning
This study compares cleaning the wound with plain salt water versus a diluted antiseptic solution after a planned C-section. The goal is to see which method better prevents infections for mothers with certain health conditions.
Loma Linda, CaliforniaAges 18 years+ - NCT06505759RecruitingPhase 1
Bromelain gel vs. chlorhexidine for gum disease treatment
This trial tests if a gel made from bromelain (a pineapple enzyme) works as well as a standard antibiotic gel to treat gum pockets caused by periodontitis. It may offer a gentler option for patients with moderate gum disease.
Bengaluru, KarnatakaAges 30–50 - NCT06689176Recruiting
Chlorhexidine wash during bladder removal surgery
This trial tests a special antibacterial wash (chlorhexidine) applied to a piece of intestine used to create a new way for urine to leave the body after bladder removal. It aims to reduce infections and improve recovery.
New York, New YorkAges 18 years+ - NCT06692582Recruiting
Saltwater rinse for treating gum disease
This study tests whether rinsing your mouth with a special saltwater solution (electrolyzed water) can help treat gum disease. It's for people who have advanced gum disease and want to try a simple, gentle addition to regular care.
LjubljanaAges 18–80 - NCT06882564RecruitingPhase 3
Resveratrol mouthwash for bad breath study
This trial tests whether a special mouthwash with resveratrol (a natural plant compound) can help reduce bad breath caused by gum-related bacteria. It might be a good option if you have bad breath from gingivitis (mild gum inflammation) and are a non-smoking dental student.
Baghdad, Bab Al-MoadhamAges 20–24 - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT07058727Recruiting
Comparing agents for partial pulp treatment on tooth survival and pain
This trial tests different materials used to treat a small area of exposed tooth pulp after cavity removal in permanent teeth without pain or infection, to see which one helps the tooth survive and causes less pain afterward.
Adana, SarıçamAges 15–55 - NCT07069166Recruiting
Good bacteria mouth rinse for gum disease and diabetes
This study tests whether a mouth rinse containing helpful bacteria (called parabiotics) can improve gum health in people who have both gum disease and type 2 diabetes. It may offer a simple, non-drug way to manage inflammation.
Pavia, LombardyAges 18–70 - NCT07104084Recruiting
Antiseptic wash and wound healing after hip replacement
This study tests whether using a special antiseptic wash during hip replacement surgery affects how well the wound heals. It may help doctors choose safer ways to clean the skin before your operation.
Monroeville, PennsylvaniaAges 18 years+ - NCT07124650RecruitingPhase 4
Sore throat after neck surgery study
This study tests if a special spray can help prevent or reduce sore throat after thyroid or parathyroid surgery. It may help you feel more comfortable after your operation.
Saint PetersburgAges 18 years+
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Common questions
- Are there clinical trials for chlorhexidine?
- Yes. Clin2 currently lists 53 recruiting chlorhexidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chlorhexidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chlorhexidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.