Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07181135Enrolling by invitationPhase 3
Finerenone for kidney disease without certain blood pressure drugs
This trial tests if finerenone can protect kidneys in people with chronic kidney disease who are not taking common blood pressure medications called ACE inhibitors, ARBs, or renin inhibitors. It may help slow kidney damage.
BarcelonaAges 18 years+ - NCT06925217Recruiting
Closed-loop insulin for type 2 diabetes and kidney disease
This study tests whether a special type of insulin delivery system (closed-loop) can help people with type 2 diabetes and chronic kidney disease. You'll wear a continuous glucose monitor and insulin pump, and researchers will track how your kidneys respond over time.
Lausanne, Canton of VaudAges 18 years+ - NCT05728216Recruiting
Using a special eye-scan to study kidney biopsy samples
This study tests whether a noninvasive “eye-scan” during a kidney biopsy can help doctors tell the difference between acute kidney injury and chronic kidney disease. If it works, it may improve how kidney problems are diagnosed in routine practice.
Chalon-sur-Saône, Saône-et-LoireAges 18 years+ - NCT06294964Enrolling by invitation
Sleep and heart health study for older adults
This study looks at how sleep patterns affect the risk of heart disease and stroke in older adults. It aims to help improve heart health through better sleep.
ShanghaiAges 60–120 - NCT06981585Recruiting
Physical effects in children with chronic kidney failure
This study looks at physical changes in children with chronic kidney failure compared to healthy children. If you join, you will have some physical measurements taken to help doctors understand how kidney disease affects the body.
IzmirAges 8–18 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT07355868RecruitingEarly Phase 1
Cell therapy for COPD
This trial is testing a new type of cell therapy called REGEND007 for people with COPD. It looks at whether the treatment can help improve how far you can walk and your overall breathing.
Yiwu, ZhejiangAges 40–80 - NCT06724315Recruiting
Studying severe COPD in Brazil
This study follows people with severe or very severe COPD to learn more about their health over time. You may qualify if your COPD causes many symptoms or frequent flare-ups.
São Paulo, São PauloAges 18 years+ - NCT06946953RecruitingPhase 1/Phase 2
Stem cell transplant for COPD: a safety and early efficacy study
This trial tests whether transplanting a patient's own lung stem cells can improve lung function in people with chronic obstructive pulmonary disease (COPD). It aims to see if this treatment is safe and helps repair damaged lung tissue.
Qionghai, HainanAges 40–80 - NCT05394922Recruiting
Study of sugar patterns in lupus anti-DNA antibodies
This study looks at the “sugar coating” on anti-DNA antibodies in people with lupus. The goal is to better understand these antibody patterns, which may help improve how lupus is studied or treated in the future.
MontpellierAges 18–80 - NCT06925373Recruiting
Housing and living conditions for better health
This study aims to learn how housing and living conditions affect health. It invites adults living in certain public housing sites in Birmingham to share their experiences to help improve community well-being.
Birmingham, AlabamaAges 18–89 - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT06619561RecruitingPhase 2
Testing vimseltinib for chronic graft versus host disease
This trial tests a new drug called vimseltinib for people with active chronic graft versus host disease (cGVHD) that hasn't gotten better after at least two prior treatments. The goal is to see if vimseltinib can help control the condition.
Duarte, CaliforniaAges 18 years+ - NCT07171216Recruiting
Parathyroid hormone control and bone density in kidney disease
This trial tests whether regulating parathyroid hormone (PTH) can improve bone density in people with advanced chronic kidney disease (CKD) who are not on dialysis. It may help you if you have stage 4-5 CKD and high PTH levels.
Herlev, Capital RegionAges 50 years+ - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT02803242Recruiting
Patient research network for people with lung symptoms
This trial enrolls adults to help build a patient-powered research network for chronic lung disease. If you join, you’ll likely be asked to complete surveys or provide information to help researchers learn how symptoms and health outcomes change over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06881979Recruiting
High-tech rehab for chronic neuromuscular diseases
This study tests a high-tech rehabilitation program for people with long-term nerve and muscle conditions. It aims to help you improve your walking and daily function using advanced technology.
GenovaAges 18–80 - NCT06961214RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This study tests a new biologic medicine, given as an injection, to see if it can reduce flare-ups in adults with COPD who have a certain type of inflammation. It may help people who still have frequent exacerbations despite using their current inhalers.
Sheffield, AlabamaAges 40–80 - NCT07648082Recruiting
Understanding Breathlessness in Lung Disease
This study explores how people experience and perceive breathlessness, whether they have a known lung condition or are healthy. Researchers want to understand breathlessness better to potentially improve how it's managed and treated.
Leicester, LeicestershireAges 18–100 - NCT07050823Recruiting
Studying chronic breathing issues and other health problems
This trial looks at how long-term health conditions like heart disease, diabetes, or high blood pressure might affect breathing problems. The goal is to better understand and help people with both issues.
São Carlos, São PauloAges 30 years+ - NCT06625944Recruiting
How viral infections affect lung disease
This study looks at how viral infections impact people with chronic lung conditions like COPD or bronchiectasis. It aims to understand symptoms and triggers better, which could help improve future treatments.
LondonAges 18 years+ - NCT07619157RecruitingPhase 1
ONO-3310 Study for Kidney Disease and Type 2 Diabetes
This early-stage trial tests a new drug called ONO-3310 in two groups: healthy adults and people with kidney disease caused by type 2 diabetes. The study aims to understand how the drug works and whether it might help protect kidney function in people with diabetes.
Fukuoka, FukuokaAges 18–64 - NCT07494409RecruitingPhase 3
A new oral medicine for anemia in dialysis patients
This trial tests a new oral medicine (AND017) for people on dialysis who have anemia (low red blood cells). It may help reduce the need for injections of standard anemia medicines.
ShanghaiAges 18–75 - NCT06620770Recruiting
Study on education program for patients on biotherapy
This trial tests whether a therapeutic education program helps people with chronic inflammatory diseases who are on biotherapy injections stick to their treatment and feel better. The program aims to improve compliance and quality of life.
LorientAges 18 years+
Hear when a new Chronic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.