Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06976177RecruitingPhase 2
MT1013 for secondary hyperparathyroidism in dialysis patients
This study tests a new injectable medicine called MT1013 for people with secondary hyperparathyroidism who are on regular kidney dialysis. It aims to see if MT1013 can help control high parathyroid hormone levels safely.
Hangzhou, ZhejiangAges 18 years+ - NCT06058585RecruitingPhase 3
Testing new treatments for chronic kidney disease
This study compares two experimental treatments—one that reduces protein in urine and another that may help control blood sugar and weight—for people with chronic kidney disease. It aims to find safer, more effective ways to slow kidney damage.
Garran, Australian Capital TerritoryAges 18 years+ - NCT04708587Recruiting
Choosing the right anti-platelet duration for advanced kidney disease
This study looks at the best length of anti-platelet medicine (which helps prevent stent clots) after a new type of heart stent. It specifically focuses on people with advanced chronic kidney disease, where bleeding and clot risks can be higher.
SeoulAges 19–84 - NCT06324136Recruiting
Personalized diagnosis for rare kidney diseases
This trial uses genetic testing to find the cause of rare kidney diseases. It is for people with unexplained kidney problems, a family history of kidney disease, or certain findings on ultrasound. The goal is to provide a more personalized diagnosis and see if this approach is cost-effective.
FlorenceAges birth–70 years - NCT07670611RecruitingPhase 4
Vitamin D2 alone or with calcitriol for children with liver disease
This trial compares two types of vitamin D—one is plain vitamin D2, the other is vitamin D2 plus a more active form (calcitriol)—to see which works better for children with liver problems and low vitamin D levels.
BangkokAges Up to 18 years - NCT07394959Recruiting
Guided hydration to protect kidneys in elderly heart patients
This trial tests a new way to manage fluids during heart procedures to prevent kidney injury. It uses a special vest that measures lung fluid to guide how much hydration you get.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07165340Enrolling by invitationPhase 1/Phase 2
Physiotherapy for leg swelling from vein disease
This study tests whether adding a special physiotherapy program can help reduce leg swelling in people with vein disease. If you have swelling from varicose veins or other vein problems and have not tried certain treatments before, you may be able to join.
Houston, TexasAges 18 years+ - NCT06810622Recruiting
NAVIGATE Kidney: Reducing Kidney Health Disparities
This study is testing a program called NAVIGATE Kidney that aims to improve kidney health and reduce racial or ethnic gaps in care. It is for adults with advanced kidney disease (eGFR 15-29) who are not yet on dialysis or had a transplant, and it involves education and support to help manage their condition.
Denver, ColoradoAges 18–75 - NCT06790498Enrolling by invitation
Long-term follow-up after renal cell therapy for kidney disease
This study follows people who previously received an experimental treatment called REACT for chronic kidney disease in earlier clinical trials. Its goal is to monitor their health over time.
Meridian, IdahoAges 30–80 - NCT06463483Recruiting
Automated Insulin Delivery for People with Advanced Kidney Disease
This trial tests an automated insulin pump system for people with diabetes who also have advanced kidney disease. It may help manage blood sugar more easily.
LondonAges 18–70 - NCT05918523Recruiting
Long-term follow-up for people treated with REACT
This study checks long-term health outcomes in people who previously received a treatment called REACT for chronic kidney disease. It may help doctors understand how safe and effective REACT is over time.
Meridian, IdahoAges 30–80 - NCT03032835Recruiting
Research study for calciphylaxis skin lesions
This study collects and stores information from people with calciphylaxis, a serious condition that causes painful skin lesions. It may help researchers learn more about the disease and improve future care.
Boston, MassachusettsAges 18 years+ - NCT07587658RecruitingPhase 4
Dupilumab after a severe COPD flare-up
This study tests whether adding the drug dupilumab to usual hospital care for a severe COPD flare-up helps patients recover better than usual care alone. It is for adults with a specific type of inflammation in their blood, and may reduce the chance of future flare-ups.
Mullica Hill, New JerseyAges 40 years+ - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Chandler, ArizonaAges 40–80 - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Birmingham, AlabamaAges 40–80 - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07052396Recruiting
Dupilumab for COPD: long-term real-world study
This study looks at how well dupilumab works over time for people with COPD who still have symptoms despite standard treatments and who have a certain type of inflammation (elevated eosinophils). It uses data from regular doctor visits and patient questionnaires to understand real-world benefits and safety.
AuerbachAges 18 years+ - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85 - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT06863194RecruitingPhase 1/Phase 2
Probiotics and kidney disease progression trial
This trial tests whether taking a probiotic supplement can slow down the decline of kidney function in people with moderate chronic kidney disease (CKD stages 3 and 4). If you have stable kidney disease and are not already taking probiotics, joining this study could help researchers find a new way to protect your kidneys.
Al Mansurah, DakahliyaAges 18 years+ - NCT07107919Recruiting
Imaging heart and kidney health in chronic kidney disease
This study uses advanced imaging (PET/MRI) to look at how kidney disease affects the heart and blood vessels. It may help doctors better understand and treat chronic kidney disease.
Qingdao, ShandongAges 18–80 - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT05236062Recruiting
Exercise during steroid treatment for GVHD
This study looks at whether doing moderate-to-vigorous exercise can reduce complications from corticosteroids in people with newly diagnosed GVHD. It may help your body tolerate steroids better, while checking exercise safety during treatment.
Boston, MassachusettsAges 18 years+ - NCT07781124Recruiting
Remote monitoring for kidney dialysis patients
This study compares the effectiveness and resource use of remote patient monitoring across different dialysis methods for people with end-stage renal disease. It aims to see if remote monitoring can improve care and outcomes.
Beijing, Beijing MunicipalityAges 18–79
Hear when a new Chronic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.