Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06877169Recruiting
Staged heart and kidney transplant study
This study compares two ways of doing a combined heart and kidney transplant. It looks at doing the surgeries in separate stages instead of all at once, to see if that is safer or works better.
Los Angeles, CaliforniaAges 18 years+ - NCT07614659Recruiting
Heart health screening for adults in Uppsala, Sweden
This study invites residents of Uppsala, Sweden who are turning 50, 55, 60, 65, 70, or 75 to participate in cardiovascular (heart and blood vessel) health screening. The goal is to help identify heart health risks early so you can take steps to stay healthy.
UppsalaAges 50–75 - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT07704567Recruiting
Using MoblO2 to maintain oxygen levels during activity
This study tests a device called MoblO2 to help people with COPD or interstitial lung disease keep their oxygen levels up during activity. If you normally use oxygen when you walk or exert yourself, this might help you stay active more safely.
Denver, ColoradoAges 25–95 - NCT03622359Recruiting
Imaging blood flow in leg artery disease using a scan
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
Columbus, OhioAges 18 years+ - NCT06046547Recruiting
Palliative care learning for lung rehab patients
This trial tests adding palliative care education to pulmonary rehabilitation for people with COPD or ILD and their caregivers. It aims to see if this helps improve symptom management and quality of life.
AveiroAges 18 years+ - NCT06366113Recruiting
Morning vs. afternoon exercise for COPD rehab
This study tests whether the time of day you exercise (morning vs. afternoon) affects how much you improve during a COPD rehabilitation program. It may help you get the most benefit from your rehab sessions.
LilleAges 18–85 - NCT06595784Recruiting
COPD and heart disease study
This study looks at people who have both COPD (a long-term lung condition) and a heart problem. The goal is to learn more about how these two conditions affect each other and to help doctors provide better care.
AlexandroupoliAges 35–99 - NCT06603246RecruitingPhase 1
Study of inhaled GDC-6988 for mucus lung diseases
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
Birmingham, AlabamaAges 18 years+ - NCT07257185RecruitingPhase 3
MHB018A for Chronic Thyroid Eye Disease
This study tests a new medication called MHB018A for people with chronic Thyroid Eye Disease (TED) that is moderate to severe. It aims to see if the drug can help improve symptoms and quality of life over time.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07274631Recruiting
Study of inflammatory lung diseases
This study collects information from people with various inflammatory lung conditions, like asthma or COPD, to better understand them and improve treatment. Healthy volunteers are also needed for comparison.
ReimsAges 18 years+ - NCT07314892Recruiting
Psychiatric health and symptom severity in GvHD patients
This study looks at how graft-versus-host disease (a complication after a bone marrow transplant) affects mental health and symptom severity. It aims to understand the connection so that doctors can better support patients.
Gdansk, Pomeranian VoivodeshipAges 18–75 - NCT07375433Recruiting
Heart failure and COPD study for patients aged 50 to 70
This trial looks at how heart failure with preserved pumping function affects people who also have COPD. It aims to understand the course of the disease and long-term outlook.
Kazan'Ages 50–70 - NCT07641309Recruiting
Health Program for Diabetes, Lung, or Heart Disease
This study measures how a health improvement program helps people with type 2 diabetes, chronic lung disease, or heart disease. Researchers will track your health before and after you participate in the program offered by your local municipality.
FrederiksværkAges 18 years+ - NCT05866302Recruiting
CT breathing-scan test to detect chronic lung injury after transplant
This study uses a special way to analyze breathing-related CT images to find early or ongoing lung injury after an allogeneic stem cell transplant. It may help clinicians recognize chronic lung complications sooner and better guide care.
Stanford, CaliforniaAges 3 years+ - NCT05596773Recruiting
Village health worker program for chronic disease care in Lesotho
This study tests a community-based care approach using trained village health workers to support people with chronic (long-term) health conditions. It may help your village get easier access to ongoing support, using a tablet-based tool and coaching from health professionals.
MaseruAges Any age - NCT07541547Recruiting
Using wearables and hearing tests to predict adult health risks
This study uses a smartphone app, a wearable device (like a fitness tracker), and hearing tests to collect health information and predict future health problems. It may help doctors identify health risks earlier so you can take steps to stay healthier.
Zhunan, MiaoliAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT07177339RecruitingPhase 3
Testing depemokimab for COPD with type 2 inflammation
This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.
Newport Beach, CaliforniaAges 40–75 - NCT07124078RecruitingPhase 2
Study of axatilimab for young people with chronic graft-versus-host disease
This study tests a new drug called axatilimab for children and teens with chronic graft-versus-host disease (cGVHD) that hasn't improved with standard treatments. The goal is to see if axatilimab works better than the usual care options. Participants will be randomly assigned to receive either axatilimab or one of several standard treatments.
Duarte, CaliforniaAges 2–17 - NCT07670988Recruiting
Kidney health in kids with inflammatory bowel disease
This study checks if children with inflammatory bowel disease (IBD) are more likely to have kidney problems. Researchers will look at medical records to compare kidney health in kids with IBD and those without.
Alessandria, PiedmontAges 2–17 - NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,260 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.