Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Birmingham, AlabamaAges 18 years+ - NCT07727915Enrolling by invitation
Using genetics to predict chronic disease risk
This trial uses genetic information to help predict your risk of developing chronic diseases. It aims to create a platform that can identify health risks earlier so you can take preventive steps.
Medellín, AntioquiaAges 18–99 - NCT07177833RecruitingPhase 1
Laser treatment for chronic Peyronie's disease
This trial tests a new type of laser treatment (fractional CO2 laser) to safely reduce penile curvature in men with chronic, stable Peyronie's disease. It may be an option if you have had the condition for at least a year with no recent changes or pain.
Ottawa, OntarioAges 18 years+ - NCT07127926RecruitingPhase 1
Belumosudil pill vs crushed pill study for chronic GVHD
This trial tests whether crushing belumosudil tablets changes how the drug works in people with chronic graft-versus-host-disease (GVHD), a complication after a stem cell transplant. It helps doctors know if taking crushed pills is as effective as whole tablets.
Houston, TexasAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT06275477Recruiting
Gallium-68 FAPI-46 PET/CT for inflammation and fibrosis
This trial uses a special PET/CT scan with a tracer called 68Ga-FAPI-46 to see if it can better detect inflammation and scarring (fibrosis) in people with chronic diseases like scleroderma, pulmonary fibrosis, or rheumatoid arthritis. The goal is to improve diagnosis and monitoring.
BrestAges 18 years+ - NCT07415551RecruitingPhase 2
New drug for chronic hives that don't respond to allergy pills
This study tests an investigational medication called lesigercept for people with chronic hives that don't get better with standard allergy pills. The goal is to see if it can reduce itching and hives better than placebo.
Sofia, SofiaAges 18–75 - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT05283512Recruiting
IV versus drink fluids to protect kidneys after CT scan
This study compares giving fluids through a vein versus drinking fluids to lower the risk of sudden kidney injury after a CT scan with contrast dye. It focuses on adults with very poor kidney function who are scheduled for an elective CT scan.
Odense C, FynAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06748118Recruiting
Reminders to help you take your medicines regularly
This study tests if simple, repeated reminders from your healthcare team can help you stick to your daily medicines for a chronic condition. You might benefit by getting more support during your hospital visits.
Angers, FranceAges 18 years+ - NCT07381738RecruitingPhase 2
Cord blood transplant for Epstein-Barr virus diseases
This trial uses donated umbilical cord blood (a type of stem cell transplant) to treat people with serious illnesses caused by the Epstein-Barr virus. It's an option for those whose disease has not responded to other treatments.
Shanghai, Shanghai MunicipalityAges 14–80 - NCT02755974Recruiting
Study of COPD flare-ups in adults with reduced lung function
This study follows people with COPD flare-ups (sudden worsening of breathing) to better understand what happens and what might help. You may be asked for consent and lung-function tests if you meet the breathing and age requirements.
LondonAges 40–100 - NCT05294029Recruiting
Study of movement and aging in adults with neuromotor disability
This study looks at how neuro-related movement problems change as people age. It may help improve care plans for adults with neuromotor disabilities by learning what happens over time.
GarchesAges 18 years+ - NCT05713149Recruiting
Treating pressure sores with surgery and anti-bacterial medicines
This study looks at whether combining a surgical skin flap with anti-bacterial treatment can improve pressure sores that are complicated by bone infection (osteomyelitis). It targets adults who have nerve/movement problems that put them at high risk for these sores.
GarchesAges 18 years+ - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT05852678Recruiting
Northern Spain health study for adults aged 40–69
This study follows people living in Cantabria to better understand health and disease patterns over time. If you’re between 40 and 69 and can consent, you may be able to join and help researchers learn what affects health in your community.
SantanderAges 40–69 - NCT06102187Recruiting
Fujian Health Study for Adults 35-75
This study is looking at the health of adults in Fujian Province over time. It may help find ways to prevent common diseases.
Fuzhou, FujianAges 35–75 - NCT05061329Recruiting
Learn how the nose’s microbes relate to health and disease
This study explores the tiny living organisms (microbes) in your nose and how they may be linked to health problems. It may help researchers better understand disease triggers and potential new prevention or treatment ideas.
Holstebro, Central JutlandAges 18 years+ - NCT07858760Recruiting
Palliative care journey from home to hospital
This study looks at the experiences of patients who come to the palliative care unit at Strasbourg University Hospital from home or through the emergency department. It aims to understand their care path to improve support for others.
StrasbourgAges 18 years+ - NCT07817589Recruiting
Adding yoga to exercise rehab for heart failure
This study tests whether adding yoga to a hospital-based cardiac rehabilitation program can improve the health and well-being of people with heart failure. It might help you feel better and manage your condition more effectively.
Dharwad, KarnatakaAges 18 years+ - NCT07825831Recruiting
Personalized heat-risk alerts for chronic conditions
This study uses AI to send personalized heat warnings to people with chronic health conditions like high blood pressure, diabetes, or obesity. The goal is to help you avoid heat-related health problems during the six-week program.
Gujranwala, Punjab ProvinceAges 18 years+ - NCT07805993Recruiting
Test of Egg White Pudding for Older Adults in Personal Care Homes
This study tests whether adding an egg white pudding to the diet is possible for older adults living in personal care homes, to help improve their nutrition.
Winnipeg, ManitobaAges 50 years+ - NCT07789899RecruitingPhase 1
Safety study of a new investigational drug in healthy volunteers
This trial tests a new medicine to see how the body handles it and whether it is safe. It is for healthy people, not for treating a disease, and helps researchers decide if the drug can move to the next stage of testing.
CambridgeAges 18–55
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.