Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,257 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06758505Recruiting
Stroke recovery study: social activities after stroke
This study tests a rehabilitation program to help people who have had a stroke get back to the social activities they enjoyed before. If you have trouble joining in activities with family or friends, this program may help you reconnect.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT02193464Recruiting
Local registry study for Crohn’s and ulcerative colitis
This study keeps a health record (a registry) of people in Daegu-Gyeongbuk with Crohn’s disease or ulcerative colitis. It helps researchers understand the illnesses in this region and improve future care planning.
DaeguAges Any age - NCT07470502Recruiting
Study of infliximab for children and teens with IBD
This trial is looking at children and teenagers with Crohn's disease or ulcerative colitis who are starting a biologic medicine called infliximab. It aims to learn more about how this treatment works in young patients.
Florence, ItalyAges 3–18 - NCT07727915Enrolling by invitation
Using genetics to predict chronic disease risk
This trial uses genetic information to help predict your risk of developing chronic diseases. It aims to create a platform that can identify health risks earlier so you can take preventive steps.
Medellín, AntioquiaAges 18–99 - NCT06275477Recruiting
Gallium-68 FAPI-46 PET/CT for inflammation and fibrosis
This trial uses a special PET/CT scan with a tracer called 68Ga-FAPI-46 to see if it can better detect inflammation and scarring (fibrosis) in people with chronic diseases like scleroderma, pulmonary fibrosis, or rheumatoid arthritis. The goal is to improve diagnosis and monitoring.
BrestAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT07127926Recruiting
Belumosudil pill vs crushed pill study for chronic GVHD
This trial tests whether crushing belumosudil tablets changes how the drug works in people with chronic graft-versus-host-disease (GVHD), a complication after a stem cell transplant. It helps doctors know if taking crushed pills is as effective as whole tablets.
Houston, TexasAges 18 years+ - NCT07177833RecruitingPhase 1
Laser treatment for chronic Peyronie's disease
This trial tests a new type of laser treatment (fractional CO2 laser) to safely reduce penile curvature in men with chronic, stable Peyronie's disease. It may be an option if you have had the condition for at least a year with no recent changes or pain.
Ottawa, OntarioAges 18 years+ - NCT07462260RecruitingPhase 2/Phase 3
Sildenafil for severe pulmonary hypertension from rheumatic valve disease
This trial tests if sildenafil can help people with severe pulmonary hypertension caused by rheumatic valvular heart disease. It aims to see if the drug improves symptoms and heart function.
Hyderābād, SindhAges 18 years+ - NCT07415551RecruitingPhase 2
New drug for chronic hives that don't respond to allergy pills
This study tests an investigational medication called lesigercept for people with chronic hives that don't get better with standard allergy pills. The goal is to see if it can reduce itching and hives better than placebo.
Sofia, SofiaAges 18–75 - NCT05283512Recruiting
IV versus drink fluids to protect kidneys after CT scan
This study compares giving fluids through a vein versus drinking fluids to lower the risk of sudden kidney injury after a CT scan with contrast dye. It focuses on adults with very poor kidney function who are scheduled for an elective CT scan.
Odense C, FynAges 18 years+ - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06748118Recruiting
Reminders to help you take your medicines regularly
This study tests if simple, repeated reminders from your healthcare team can help you stick to your daily medicines for a chronic condition. You might benefit by getting more support during your hospital visits.
Angers, FranceAges 18 years+ - NCT07381738RecruitingPhase 2
Cord blood transplant for Epstein-Barr virus diseases
This trial uses donated umbilical cord blood (a type of stem cell transplant) to treat people with serious illnesses caused by the Epstein-Barr virus. It's an option for those whose disease has not responded to other treatments.
Shanghai, Shanghai MunicipalityAges 14–80 - NCT06859060Recruiting
Improving health for people with serious mental illness
This study helps people with serious mental illness like schizophrenia or bipolar disorder who also have chronic health conditions (e.g., diabetes, overweight) get better overall care. It focuses on improving health and wellness through preventive medical care in Puerto Rico.
Mayagüez, Puerto RicoAges 21 years+ - NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Huntsville, AlabamaAges 18 years+ - NCT07304154RecruitingPhase 1
Study of KITE-363 for autoimmune nerve diseases
This trial tests a new treatment called KITE-363 for people with certain autoimmune nerve diseases, such as multiple sclerosis, myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy, that have not responded well to standard therapies. The goal is to see if it is safe and effective.
Newport Beach, CaliforniaAges 18–75 - NCT07490652Recruiting
Healthy food access for rural Latino communities
This study tests a program that makes it easier for Latino families in rural Washington to buy and eat more fruits and vegetables. If you are the main shopper in your household and eat few fruits and vegetables now, this program could help you and your family make healthier choices.
Granger, WashingtonAges 18 years+ - NCT06750601Recruiting
Using rehab data for research on physical disabilities
This study collects information from people receiving rehabilitation care. The data may be used to improve treatments for physical disabilities and chronic diseases.
GroningenAges Any age - NCT06958016Recruiting
Tryptase levels in stable coronary artery disease
This study looks at levels of tryptase, a protein in your blood, in people with stable coronary artery disease. It aims to see if these levels are linked to heart health, which could help doctors better understand and manage your condition.
Athens, AtticaAges 18–85 - NCT05551780Recruiting
Study for treating calcium blockages in leg artery disease
This trial tests a treatment approach for certain long-lasting, calcium-heavy blockages in the leg arteries that have no normal blood flow past the blockage. If you have these “total occlusions” and symptoms like walking pain or critical limb symptoms, this study may offer a new way to open the artery and restore blood flow.
Fort Lauderdale, FloridaAges 19 years+ - NCT05294029Recruiting
Study of movement and aging in adults with neuromotor disability
This study looks at how neuro-related movement problems change as people age. It may help improve care plans for adults with neuromotor disabilities by learning what happens over time.
GarchesAges 18 years+ - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,257 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.