Chronic Disease clinical trials

Cannabis product for gynecologic pain study

This trial tests a new cannabis-based product to see if it helps with gynecologic pain (like endometriosis). It looks at how the product works and whether it is safe and effective.

Hypnosis during noninvasive breathing support for ICU lung illness

This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.

Long-term follow-up study for people with COPD

This study follows people with COPD over time to better understand their lung health and how it changes. It may help researchers and doctors learn what factors affect breathing and long-term outcomes.

Cell treatment through a breathing tube for severe emphysema

This trial tests a cell-based treatment placed into the lung using an airway valve, to help people with severe emphysema breathe easier. You may be eligible if your emphysema is uneven in the lungs and testing suggests your “collateral ventilation” is low, meaning the treatment area may benefit more from blocking airflow.

Strength training study for people with COPD

This trial tests whether a maximal strength training program can help people with COPD who are stable. It is looking at people with moderate-to-severe airflow limitation and excludes several other lung and health problems.

Tested lung imaging scans in stable COPD patients

This study compares two ways of seeing how well your lungs work: a special MRI scan and another scan that uses a different gas. It may help researchers find which imaging test best reflects lung function in people with COPD.

Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups

This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.

Study gut-like lung bacteria and inflammation in early COPD

This study looks at the lung’s tiny bacteria (microbiome) and inflammation in people with early COPD who have a smoking history. It compares them with smokers who have normal breathing tests, to better understand what may drive COPD early on.

Study bone loss from steroid use in people with inflammatory disease

This study looks at how steroid medicines (called glucocorticoids) affect bone strength in people with long-term inflammatory rheumatic conditions or psoriasis. It may help improve how doctors check and manage osteoporosis risk and bone metabolism over time.

Study kidney samples to understand autoimmune, inflammatory, and diabetic disease

This trial collects and studies kidney tissue samples to better understand what drives kidney problems linked to autoimmune, inflammation, and diabetes. Your participation may help researchers develop better ways to diagnose and treat these conditions.

Share information and donate tissue samples for pancreatic illnesses

This study collects health information and tissue samples from people with pancreatic cancer or other pancreatic conditions. Your participation may help researchers better understand these diseases and improve future care.

HRS-9821 inhalation treatment for moderate to severe COPD

This trial tests whether an inhaled medication called HRS-9821 can help people with moderate to severe COPD (chronic obstructive pulmonary disease) breathe better and reduce symptoms. You inhale the medication, and researchers will measure how well your lungs work and how you feel over time.

Using sound waves to collect lung mucus samples in COPD patients

This trial is testing whether a device that uses sound waves can help collect lung mucus samples more easily in people with COPD. It compares two groups: current smokers and ex-smokers, to see if the device works differently for them.

Pulmonary and Total Blood Volume in COPD

High-flow nasal oxygen versus non-invasive ventilation for COPD

This trial compares two breathing support methods for people hospitalized with COPD and mild-to-moderate carbon dioxide retention. It aims to see if high-flow nasal oxygen is as effective as the standard mask-based ventilation.

Long-term Safety of Tozorakimab in COPD Patients

This study follows patients who previously took part in a tozorakimab trial to see how safe the drug is over time. Tozorakimab is an antibody treatment designed to reduce flare-ups (exacerbations) in people with COPD, a chronic lung disease.

Exercise order in lung rehab for COPD patients

This trial tests if the order of exercises during pulmonary rehabilitation can improve muscle strength in people with COPD. It compares different exercise sequences to find the most effective approach.

Study of KIT2014 for moderate to severe COPD

This trial tests a new medicine called KIT2014 in people with moderate to severe COPD. It aims to see if the drug is safe, tolerable, and helps improve breathing and COPD symptoms.

Continuous vs. interval exercise for COPD

This trial compares two types of exercise training—steady moderate exercise versus short bursts of higher intensity—to see which is more helpful for people with COPD. It aims to find a better way to improve your breathing and fitness.

Breathing and step exercises for COPD wellness

This study tests a program combining breathing training with step exercises to see if it improves breathing, exercise ability, and quality of life in people with COPD. You may join if you have COPD and are able to do light exercise and fill out questionnaires.

Safety Study of WIN378 for Moderate-Severe COPD

This study tests a new drug called WIN378 in people with moderate-to-severe COPD (chronic lung disease). It will check if the drug is safe and how the body processes it, which may help improve breathing and reduce flare-ups.

Biologics for asthma and COPD

This study looks at how well medicines called biologics work for people with asthma or COPD. Biologics are special shots that target certain parts of the immune system to reduce inflammation. Researchers want to see if these treatments can help control symptoms and prevent flare-ups.

Understanding body signals during COPD flare-ups

This study explores how people with COPD perceive body signals during a sudden worsening of symptoms (exacerbation) that requires a hospital stay. It aims to improve symptom management and patient care.

Breztri safety study for COPD and asthma patients in Korea

This study collects information on how Breztri (a medicine for COPD and asthma) works in real-life patients who have just started taking it. It helps ensure the medicine is safe and effective for people like you.