Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT06477549RecruitingPhase 2
Comparing Two Drug Combinations for Stem Cell Transplant
This study compares two different drug combinations (BeFluBu and FluBuRux) used before a stem cell transplant from a half-matched (haploidentical) donor. The goal is to see which combination works better to prepare your body for the transplant and control your blood cancer.
Saint PetersburgAges 18–75 - NCT07025538RecruitingPhase 1
Preventing chronic graft-versus-host disease with ruxolitinib
This trial tests whether the drug ruxolitinib, given based on a blood test that predicts risk, can prevent chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It may help people who have a higher risk of developing this complication.
Duarte, CaliforniaAges 18 years+ - NCT05807932RecruitingPhase 1/Phase 2
Venetoclax added to conditioning before stem cell transplant
This trial tests adding venetoclax to a standard “conditioning” chemotherapy plan before an allogeneic stem cell transplant (using a donor) for certain bone marrow cancers. It aims to improve how well the transplant works and how safe this combination is for people with MDS, CMML, or sAML.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT07147296Recruiting
Implant to manage blood pressure swings after spinal cord injury
This trial tests an implanted device that may help control drops in blood pressure caused by spinal cord injury. If you often feel dizzy or lightheaded due to low blood pressure, this study could explore whether the device improves stability.
Little Rock, ArkansasAges 18–75 - NCT07218510RecruitingPhase 2
Venetoclax, obinutuzumab, then epcoritamab for untreated CLL/SLL
This trial tests a new combination of three drugs for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have not had treatment yet. The goal is to see if this approach helps control the disease with fewer side effects.
Duarte, CaliforniaAges 18 years+ - NCT06848140Recruiting
Brain stimulation for word-finding problems after TBI
This study tests whether non-invasive brain stimulation can help people with chronic traumatic brain injury (TBI) find words more easily. It involves sessions at Beth Israel Deaconess Medical Center in Boston.
Boston, MassachusettsAges 18–85 - NCT06958705RecruitingPhase 2
Testing venetoclax after BTK inhibitor for CLL
This trial tests giving venetoclax to people with CLL who are already taking a BTK inhibitor and have stable disease. The goal is to see if adding venetoclax can help eliminate any remaining CLL cells.
Nanjing, JiangsuAges 18–80 - NCT06735664RecruitingPhase 1
Zanubrutinib and odronextamab for Richter's transformation
This trial tests a combination of two targeted drugs for people with Richter's transformation, an aggressive lymphoma that can develop from CLL. The goal is to see if this combination can help control the disease.
Duarte, CaliforniaAges 18 years+ - NCT06731894RecruitingPhase 2
Cannabis for nerve pain after chemotherapy in breast and colon cancer survivors
This trial tests whether a cannabis-based product can reduce nerve damage (neuropathy) caused by chemotherapy in people who have finished treatment for breast or colon cancer. It focuses on survivors who still have pain, numbness, or tingling in their hands or feet.
Duarte, CaliforniaAges 18 years+ - NCT07313878Recruiting
Kidney health study in young leukemia patients using ultrasound
This study tests whether a special ultrasound technique can detect early kidney damage in children and teens with acute lymphatic leukemia, before standard tests show any problems.
Erlangen, BaveriaAges 3–17 - NCT07235501Recruiting
Studying immune cells in chronic GVHD after stem cell transplant
This study looks at immune cells in the blood and tissues of people who have had a stem cell transplant. It aims to understand chronic graft-versus-host disease (GVHD), a common complication, so doctors can better detect and treat it.
Duarte, CaliforniaAges 7 years+ - NCT06401993Recruiting
Brain connection study of tinnitus treatment with Chinese medicine
This study tests a traditional Chinese medicine treatment called 'Dao qi Tong Luo' for chronic tinnitus. It uses a safe brain scan (fNIRS) to see how the treatment affects brain connections related to hearing.
HangzhouAges 20–55 - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT06676384RecruitingPhase 4
Testing additional drugs for IgA nephropathy in South Asian patients
This trial is testing if adding another approved drug to standard treatment can slow kidney function decline in people with IgA nephropathy. It aims to find better options for South Asian adults with this condition.
Nadiād, GujaratAges 18–65 - NCT06287944RecruitingPhase 1
Targeted radiation and chemo before donor stem cell transplant
This trial tests a new approach: giving a targeted radioactive antibody (attached to a drug that finds CD38 on cancer cells) along with low-dose chemotherapy and targeted radiation to the bone marrow before a donor stem cell transplant. The goal is to prepare the body for the transplant while killing remaining cancer cells more precisely.
Duarte, CaliforniaAges 18–70
Hear when a new Chronic Medical Conditions trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 209 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.