Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03645486Recruiting
Gene therapy for chronic granulomatous disease (CGD)
This trial tests a lentiviral gene therapy to improve immune function in people with CGD, a condition where the body can’t fight certain infections well. It may help by addressing the underlying genetic problem, but it also requires a procedure to collect immune cells and special “conditioning” medicines beforehand.
Shenzhen, GuangdongAges Any age - NCT07021495Recruiting
Skin disease study to improve treatment choices
This study looks at different skin diseases to find markers that can help guide treatment. It tests new treatments for several conditions like eczema, psoriasis, and lupus, with the goal of personalizing care.
Nijmegen, GelderlandAges 18 years+ - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Dothan, AlabamaAges 18–80 - NCT02675959RecruitingPhase 2
Transplant with defibrotide for sickle cell disease
This trial tests a stem cell transplant from a half-matched donor using a strong conditioning regimen and a drug called defibrotide to protect organs. It aims to cure sickle cell disease in patients who have had serious complications like stroke, chest syndrome, or frequent pain episodes.
Los Angeles, CaliforniaAges 6 months–21 years - NCT05584761RecruitingPhase 1/Phase 2
Cord blood stem cells plus azacitidine for advanced blood cancers
This trial tests whether adding donated cord blood stem cells to azacitidine can improve outcomes for people with advanced MDS, CMML-2, or a certain type of AML. It may help by giving the treatment a stronger chance to control abnormal blood-forming cells.
Nanjing, JiangsuAges 18–80 - NCT07116174Recruiting
Testing a new amniotic membrane dressing for diabetic foot ulcers
This study tests a new wound dressing made from amniotic membrane, called Xcell Amnio Matrix, to see if it helps heal diabetic foot ulcers that have not healed with standard treatments. If you qualify, you would receive the dressing along with regular wound care.
Fresno, CaliforniaAges 18 years+ - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT06281431Recruiting
Study comparing two needle types for nerve blocks to reduce pain
This trial compares a special echogenic (ultrasound-visible) needle with a standard needle for nerve blocks during surgery. The goal is to see which works better for preventing both short-term and long-term pain after operations like chest, abdomen, or limb surgeries.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07052539Recruiting
Kidney disease in heart failure with obesity
This study looks at how kidney disease relates to a type of heart failure (called HFpEF) that often happens in people with obesity. It will help doctors understand this connection better.
Jackson, MississippiAges 18–75 - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99 - NCT06168058Recruiting
Pelvic vein embolization for chronic pelvic pain
This trial tests if blocking enlarged veins in the pelvis (called embolization) can reduce long-term pelvic pain that hasn't improved with other treatments. It may help women whose pain is worse when standing or walking and better when lying down.
New Hyde Park, New YorkAges 18–75 - NCT06059391RecruitingPhase 2
Vaccine for stem cell donors to prevent CMV
This trial tests whether giving a CMV vaccine to stem cell donors can help protect recipients from CMV infection after transplant. It is for adults with specific blood cancers who are CMV-positive and have a matched related donor.
Duarte, CaliforniaAges 18–75 - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT06281756RecruitingEarly Phase 1
CBT and Trazodone for Sleep and Blood Pressure in Insomnia
This trial tests whether cognitive behavioral therapy (a type of talk therapy for sleep) and/or the medication trazodone can improve sleep and lower blood pressure in people with chronic insomnia. You must be 18 or older and have ongoing trouble sleeping.
Denver, ColoradoAges 18 years+ - NCT06782724RecruitingPhase 2
Psilocybin therapy for distress in advanced illness
This trial tests whether a single dose of psilocybin (a psychedelic medicine) can help reduce depression and distress in people with advanced lung disease, ALS, multiple sclerosis, or Parkinson's. You would receive preparation, the drug, and follow-up support in a safe, supervised setting.
PragueAges 18 years+ - NCT05715697Recruiting
Kidney artery treatment for heart failure with normal heart pumping
This study tests whether renal denervation (a procedure to reduce overactive signals in kidney arteries) can help people who have heart failure but keep a normal pumping ability and still have high blood pressure. It aims to improve blood-pressure control and heart function in this specific group.
Ürümqi, XinjiangAges 21–80 - NCT06464926Recruiting
Electrical stimulation for chronic nausea and vomiting
This study tests a device that sends mild electrical pulses to your stomach to help with chronic nausea and vomiting. It is for people who have had nausea for over 6 months, have normal stomach emptying, and have not found relief from standard medications.
Scottsdale, ArizonaAges 18 years+ - NCT06940986Recruiting
Holistic pain self-management for military health system patients
This trial tests a holistic pain self-management program for people with long-term muscle or bone pain. It aims to help you take control of your pain through education and support, without relying only on medications.
Fairbanks, AlaskaAges 18 years+ - NCT06106685RecruitingPhase 1/Phase 2
Washed microbiota transplant for chronic constipation
This trial tests a treatment called washed microbiota transplantation (a procedure that delivers healthy gut bacteria to your colon) for adults with chronic constipation. The goal is to see if it can improve bowel movements without the need for laxatives.
Nanjing, JiangsuAges 18–70 - NCT06405646Enrolling by invitation
Cannabidiol and Cannabinol for Chronic Jaw Muscle Pain
This study tests whether certain compounds from the cannabis plant (CBD and CBN) can help relieve long-term pain in the jaw muscles. It is for adults with chronic orofacial pain who have not recently taken medications that affect the nerves or muscles.
WroclawAges 18–80 - NCT07351851Recruiting
Exercise for back pain and urine leakage in women
This study tests whether a special exercise program called PEMM (which combines pelvic floor and core exercises) can help women with both chronic low back pain and urinary incontinence. It is designed for women who have had back pain and urine leakage for at least 3 months.
Doha, Baladiyat ad DawhahAges 18–65 - NCT03533816RecruitingPhase 1
Gamma delta T-cell infusion after stem cell transplant
This early-phase study tests giving a special immune-cell treatment after an allogeneic (donor) stem cell transplant, plus a medication given after transplant to help the new immune system work better. It may help prevent or treat cancer returning after transplant.
Westwood, KansasAges 18–65 - NCT07056569Recruiting
Testing a dermatitis cream for adults and children with eczema
This study tests a medical cream for people with atopic or contact dermatitis (eczema). It aims to see how well the cream works and if it is safe for both adults and children over 6 months old.
MilanAges 6 months–65 years
Hear when a new Chronic Medical Conditions trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 209 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.