Clinical trials
Chronic Pain Syndrome clinical trials
Below are recruiting chronic pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 231 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80 - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99 - NCT05920382Recruiting
Radiofrequency treatment for long-term knee pain after knee surgery
This trial studies whether a radiofrequency procedure can reduce chronic knee pain after knee replacement surgery. It may help people who still have bothersome pain between 6 months and 5 years after their operation, as long as their pain pattern and medications are stable.
Barcelona, CataloniaAges 18 years+ - NCT05925036RecruitingPhase 1
Cell therapy trial for pain from long-term pancreatitis
This Phase 1 study tests a new cell-based treatment to reduce pain caused by chronic pancreatitis. It’s designed mainly to check safety first, and it may help people with ongoing, opioid-stable pancreatic pain.
Charleston, South CarolinaAges 18–75 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT06115083Recruiting
Pelvic floor training for men with chronic pelvic pain
This trial tests if pelvic floor muscle training can reduce chronic pelvic pain in men. It also looks at how well patient-reported symptoms match physical exam findings.
StockholmAges 18 years+ - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT06205342RecruitingEarly Phase 1
Stem cells for chronic pancreatitis pain
This trial tests whether a new treatment using stem cells can safely reduce long-term pain from chronic pancreatitis. It is for people who have had pancreatic pain for at least 6 months and are already taking daily pain medicine.
Charleston, South CarolinaAges 18–75 - NCT06209346Recruiting
Remote physical therapy for chronic pelvic pain from endometriosis
This trial tests if a physical therapy program done at home through video calls can help reduce chronic pelvic pain in people with endometriosis. If you have ongoing pelvic pain and have already had medical or surgical treatment, this study may offer a new way to manage your pain.
Alcalà de Henares, MadridAges 18–55 - NCT06299683Recruiting
Pain type and bladder pain syndrome treatment study
This study is testing if the type of pain you feel can help predict which treatments work best for interstitial cystitis (a condition that causes bladder pain and pressure). It may help match you with more effective care.
Franklin, TennesseeAges 18 years+ - NCT06360965Recruiting
Acupoint patch for pelvic pain after PID
This trial tests a skin patch treatment (acupoint application) placed on specific points of the body to help relieve ongoing pelvic pain from pelvic inflammatory disease. It may be a good option if you have moderate pain and ultrasound findings of tubal thickening or fluid.
BeijingAges 18–50 - NCT06385977Recruiting
Risk Factors for Chronic Prostatitis in Northwest China
This study looks for risk factors in men from Northwest China with long-term pelvic or perineal pain (chronic prostatitis) compared to healthy volunteers.
Xi'an, ShaanxiAges 18 years+ - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06507267Recruiting
Pain and symptoms in pelvic congestion syndrome
This study looks at how pain and other symptoms relate to a condition called pelvic congestion syndrome, which happens when veins in the pelvis become enlarged. It may help doctors better understand and treat this cause of long-term pelvic pain.
IstanbulAges 18–50 - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT07685847Recruiting
Suppository for chronic prostatitis or pelvic pain relief
This trial tests a rectal suppository (Prospidol®) to see if it can relieve pain and other symptoms in men with long-term prostatitis or pelvic pain. It is for men who have not had treatment recently and have no signs of infection or other serious illnesses.
Avellino, AvellinoAges 18–60 - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+ - NCT06816095Recruiting
Ozone therapy for pelvic pain after gynecological cancer treatment
This study is looking at whether ozone therapy can help relieve chronic pelvic pain caused by gynecological cancer treatments like radiation and chemotherapy. It aims to understand how the treatment works at a molecular level.
Las Palmas, Las PalmasAges 18 years+ - NCT06825390Recruiting
Ear stimulation and brain imaging for chronic low back pain
This study tests if a non-invasive ear stimulation technique can change brain activity linked to chronic low back pain. You would have a brain scan before and after the treatment to see how your brain responds.
Pittsburgh, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for chronic pain syndrome?
- Yes. Clin2 currently lists 231 recruiting chronic pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.