Clinical trials · New York
Chronic pain clinical trials in New York
We’re tracking 29 recruiting chronic pain studies with a site in New York — including Phase 1/Phase 2, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in New York
- NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Rochester, New YorkAges 18 years+ - NCT06288282Recruiting
Predicting pain and opioid misuse in chronic back pain
This study looks at how thinking and behavior affect long-term pain and opioid use in people with chronic lower back pain. It aims to find better ways to manage pain and prevent medication misuse.
New York, New YorkAges 18 years+ - NCT06800209RecruitingPhase 2
Pain Reprocessing Therapy for ongoing knee pain after replacement
This study tests if Pain Reprocessing Therapy can help reduce knee pain that continues 3 months after a knee replacement. It uses a telehealth approach so you can participate from home.
New York, New YorkAges 18 years+ - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT05127616Recruiting
Trial for chronic pelvic pain: CBT vs education/support
This study tests whether structured talking therapy (CBT) or education/support helps reduce chronic pelvic pain problems in adults. It compares two approaches over time and uses symptom diaries and follow-up check-ins to see which works better.
Buffalo, New YorkAges 18–70 - NCT05285683RecruitingPhase 2
Study brain dopamine in people with chronic pain
This Phase 2 study looks at how a brain chemical called dopamine is involved in long-lasting pain. You may be able to join if you have chronic pain for over a year and your pain score is high enough, and if MRI and health checks are safe for you.
Rochester, New YorkAges 18 years+ - NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
The Bronx, New YorkAges 18 years+ - NCT07225049Recruiting
Integrated treatment for PTSD and chronic pain
This study tests a combined therapy for people who have both PTSD and chronic pain. It aims to see if treating both conditions together is more helpful than treating them separately.
New York, New YorkAges 18 years+ - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Rochester, New YorkAges 18 years+ - NCT06168058Recruiting
Pelvic vein embolization for chronic pelvic pain
This trial tests if blocking enlarged veins in the pelvis (called embolization) can reduce long-term pelvic pain that hasn't improved with other treatments. It may help women whose pain is worse when standing or walking and better when lying down.
New Hyde Park, New YorkAges 18–75 - NCT04270617Recruiting
Yoga practice for long-term back pain
This study looks at whether regular yoga helps people with chronic (long-lasting) back pain. If you can safely take part in yoga sessions and your pain has lasted at least 3 months, you may be able to enroll.
New York, New YorkAges 18 years+ - NCT06083597Enrolling by invitation
Developing a pelvic pain questionnaire for women
This study aims to develop a new questionnaire to better understand and measure chronic pelvic pain in women, especially when it's linked to enlarged pelvic veins. You will be asked to take part in interviews and fill out surveys to help create a tool that reflects your experience.
New York, New YorkAges 18–60 - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06413277Recruiting
ECAP-controlled spinal cord stimulation for chronic pelvic pain
This trial tests a new type of spinal cord stimulator that uses closed-loop technology to treat chronic pelvic pain caused by a known injury. It may be an option if your pain is severe and hasn't responded to other treatments.
New York, New YorkAges 18 years+ - NCT06306157Enrolling by invitationPhase 4
Low dose naltrexone for complex regional pain syndrome
This trial tests whether a low dose of naltrexone, a medication that may help calm overactive immune and pain signals, can reduce pain and improve daily life in people with complex regional pain syndrome (CRPS), a chronic condition that often causes severe pain and swelling.
New York, New YorkAges 18–85 - NCT01765777Recruiting
Osteopathic hands-on therapy and light treatment for long-term low back pain
This trial studies whether hands-on osteopathic treatment and a type of light (phototherapy) can reduce chronic low back pain. It may help people who have had non-specific low back pain for at least 3 months.
Old Westbury, New YorkAges 18–65 - NCT07641517RecruitingPhase 2
Testing LY4065967 for chronic knee osteoarthritis pain
This study tests an experimental drug called LY4065967 to see if it can help reduce pain from osteoarthritis in the knee. You'll be in the trial for several months, with regular check-ins and pain assessments.
Rochester, New YorkAges 40 years+ - NCT05981105Recruiting
Recovery and Chronic Pain After Knee Replacement
This study tests a special recovery program after knee replacement surgery to see if it helps reduce long-term pain. You may be eligible if you are having a first-time knee replacement for osteoarthritis, are between 18 and 65, and live near the hospital.
New York, New YorkAges 18–75 - NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain
This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.
The Bronx, New YorkAges 18 years+ - NCT06094257Recruiting
Study on sensation and satisfaction after mastectomy
This study looks at how people feel after mastectomy, including transgender patients and those having nipple-sparing surgery. It aims to understand sensation and satisfaction to improve future care.
New York, New YorkAges 18 years+ - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Port Jefferson Station, New YorkAges 18 years+ - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06795386Recruiting
Widespread pain after rapid weight loss in Black and Hispanic adults
This study looks at whether rapid weight loss from bariatric surgery leads to long-term widespread pain in Black and Hispanic adults. The goal is to understand how weight loss affects pain and find better ways to help people manage it.
New York, New YorkAges 18–75 - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
New York, New YorkAges 18 years+
Chronic pain trials by city in New York
Where these studies are running in New York
Institutions with a site for the recruiting chronic pain studies listed above.
- Weill Cornell Medicine · 6 studies
- Hospital for Special Surgery · 3 studies
- Rochester Clinical Research, LLC · 3 studies
- NYU Langone Health · 2 studies
- Ainsworth Institute of Pain Management
- Columbia University Irving Medical Center
- Montefiore Medical Center
- Montefiore Multidisciplinary Pain Program
What taking part in a chronic pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Chronic pain trials in other states
Common questions
- Are there chronic pain clinical trials in New York?
- Yes. We're currently tracking 29 recruiting chronic pain studies with a site in New York, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic pain study in New York?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in New York to take part?
- Not necessarily. These studies have a site in New York, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic pain studies open in New York regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.