Clin2
NCT05285683Possibly a fitRecruiting

Study brain dopamine in people with chronic pain

Chronic Pain

Treatments studied

Part of Pain clinical trials.

This Phase 2 study looks at how a brain chemical called dopamine is involved in long-lasting pain. You may be able to join if you have chronic pain for over a year and your pain score is high enough, and if MRI and health checks are safe for you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
10 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be age 18 or older and generally in stable health
  • Speak, read, and understand English and sign informed consent
  • Have chronic pain for more than 1 year and your pain is at least 40 out of 100
  • Be able to do a required finger-and-eye tracking practice task during the study
  • Be able to have an MRI (no metal in the body, not pregnant, and you must not be severely claustrophobic)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain

This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.

Paris
NCT06502496Not yet recruiting· Phase 3
Behavioral study of creativity and motivation in chronic pain

This study uses brain scans (MRI) and behavioral tasks to explore how creativity and motivation work in people living with chronic pain. It aims to understand the brain circuits involved, which could lead to better pain treatments.

NCT05905419Recruiting
Brain scan study of opioid effects in women with pain

This study uses brain imaging (MRI) to understand how opioid medications may affect the brain in women. People with chronic pain who take opioids (or do not) and healthy women without chronic pain may be invited to participate.

Durham, North Carolina
NCT06019793Enrolling by invitation
Recording brain signals during deep brain stimulation for pain

This study tests whether recording brain activity during deep brain stimulation (DBS) for chronic pain can help improve future treatments. It is for people with long-lasting, severe pain that hasn't been helped by other treatments.

Phoenix, Arizona
NCT07432841Recruiting
Personalized brain stimulation for chronic pain

This trial tests a personalized form of brain stimulation (high-definition tDCS) to treat chronic pain that has not improved with other treatments. If you have had pain for at least 6 months and it is still moderate to severe, this may be an option to explore.

Milan
NCT07266103Recruiting
Personalized brain stimulation for chronic pain study

This study tests whether personalized sessions of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce chronic pain. It aims to understand how this treatment works and how it might be tailored to individuals.

Gistrup

Hear when a new Chronic pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.