Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT05734313Recruiting
Teletherapy CBT for anxiety and depression in people with diabetes
This trial tests a unified, talk-therapy program delivered by video (telemedicine) to help with anxiety and depressive symptoms. If you have type 1 diabetes and symptoms of anxiety or depression, it may help you learn coping skills and improve mood.
Boston, MassachusettsAges 18–64 - NCT06077695Recruiting
Memory training after head injury
This study tests a computer-based training program to help improve working memory after a moderate or severe head injury. It is designed for people who still have memory problems at least 3 months after their injury.
ToulouseAges 18–60 - NCT04109027Recruiting
Training program to improve thinking and memory for veterans
This trial tests an intensive skills-training program to help with thinking and memory problems after a mild-to-moderate traumatic brain injury (TBI). It’s designed for veterans who are at least 6 months past the injury and still notice cognitive symptoms that affect daily goals like work or school.
Sacramento, CaliforniaAges 21–60 - NCT06013579Recruiting
Exercise study for older adults with HIV
This study tests whether high-intensity exercise can help improve thinking and memory, and build lasting exercise habits, in older adults living with HIV who feel tired and are not very active.
Birmingham, AlabamaAges 50–80 - NCT06017505Enrolling by invitation
Using eSAGE for early detection of cognitive decline
This study uses a simple computer-based self-assessment (eSAGE) to detect early signs of memory or thinking problems. It may help identify cognitive impairment sooner and track changes over time.
Columbus, OhioAges 50 years+ - NCT06002919Recruiting
MindWalk for older South Asian caregivers of people with cognitive disabilities
This study tests a program that combines physical activity and mindfulness practices to help reduce stress in older South Asian caregivers. Participants will get a Fitbit tracker and receive text messages to support their well-being.
Bolingbrook, IllinoisAges 45 years+ - NCT06029114Enrolling by invitation
Brain scan study for memory problems
This study uses a special MRI to look at brain stiffness in people with normal memory, mild memory problems, or Alzheimer's disease. The goal is to see if this scan can help tell the difference between these groups.
Rochester, MinnesotaAges 18–100 - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT06015932Recruiting
Group stress management for cancer patients
This trial tests whether group therapy sessions can help cancer patients cope with stress. If you're feeling moderately distressed and have been treated for cancer recently, this program might help you manage those feelings.
Rochester, MinnesotaAges 18 years+ - NCT05998031Recruiting
Testing brain stimulation for memory in mild memory loss
This study tests if a gentle brain stimulation technique called tDCS, combined with memory training, can help older adults with mild cognitive impairment (MCI) improve their working memory. You'll have MRI scans and attend training sessions.
Gainesville, FloridaAges 60–95 - NCT05959434RecruitingPhase 2
Therapy program to reduce drinking relapse and PTSD symptoms
This Phase 2 study tests a combined therapy approach for people who have both alcohol use disorder and post-traumatic stress disorder (PTSD). It aims to help you process stressful memories and lower the chances of relapse back to heavy drinking.
Charleston, South CarolinaAges 18 years+ - NCT05965518Recruiting
High-intensity exercise for brain and blood-vessel health in HIV
This trial tests whether high-intensity exercise can improve blood-vessel health and brain function in adults with HIV who are not very active and have thinking/memory problems. If you qualify, you’ll be asked to safely complete exercise and other study assessments.
Birmingham, AlabamaAges 50 years+ - NCT05973110Recruiting
Virtual reality training to improve thinking in psychosis
This trial tests whether a virtual reality program can help people living with psychosis improve thinking and daily functioning. It may help if your symptoms are currently stable and you can safely use the VR equipment.
Ottawa, OntarioAges 18–60 - NCT05927974Recruiting
Brain mapping during surgery for hard-to-control epilepsy
This trial studies how the brain’s control networks work during a surgery-related procedure for people with epilepsy that hasn’t improved with usual treatments. If you qualify, you may do specific tasks while the team maps and measures brain activity to better understand and guide care.
Birmingham, AlabamaAges 18 years+ - NCT04855825Recruiting
Wearable robotic exoskeleton to improve walking and thinking in MS
This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.
West Orange, New JerseyAges 18–75 - NCT05907343Recruiting
Brain stimulation study for memory and thinking concerns
This study tests a new brain stimulation method that may help improve memory and thinking in older adults who have memory concerns. It uses a safe, non-invasive technique called transcranial magnetic stimulation (TMS) that sends magnetic pulses to the brain.
Austin, TexasAges 18–90 - NCT05881239Recruiting
Remote smell tests to track early Alzheimer’s health changes
This trial uses remote, at-home (or remote) smell-based testing to help researchers assess health in people with preclinical Alzheimer’s disease and in control participants. It may help by showing how well smell-related changes can signal disease status over time.
Boston, MassachusettsAges 18–100 - NCT05897619Recruiting
CBT skills app for pregnancy and postpartum stress and coping
This study tests whether a new phone app that teaches “cognitive behavioral therapy” (CBT) skills is helpful and easy to use for people who are pregnant or recently gave birth. It also checks safety and whether participants feel the app is acceptable to use over time.
New York, New YorkAges 18 years+ - NCT05907265Recruiting
Virtual reality sessions to improve thinking after chemotherapy
This study tests whether immersive virtual reality training can improve thinking and concentration in adults who have had ongoing thinking problems after chemotherapy. It may help by using guided VR tasks that aim to support cognitive skills during recovery.
TerrassaAges 18–65 - NCT05858008Recruiting
Time-restricted eating program for women with mild memory loss
This trial tests whether a structured “time-restricted eating” schedule is practical and safe for women with mild cognitive impairment (mild memory/thinking changes). You may be able to join if your routine and health conditions fit the study rules, and they will focus on eating timing and daily patterns.
Lexington, KentuckyAges 45–95 - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05826379Enrolling by invitation
Daily goal setting to boost movement and brain health
This trial tests whether a daily goal-setting program and activity tracking can increase everyday physical activity and support thinking/brain health in midlife. You may be asked to wear devices and meet activity-monitoring requirements during the study.
Hershey, PennsylvaniaAges 30–70 - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.