Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05808153Recruiting
Brain scans and thinking tests to track Huntington’s progression
This study uses special brain imaging and memory/thinking tests to find early “markers” that can predict how Huntington’s disease will progress over time. You may qualify as someone with early-stage Huntington’s or as a healthy control, if you meet specific safety and scoring requirements.
Créteil, Île-de-France RegionAges 18–65 - NCT05814822Recruiting
CBT for sleep problems in adults using cannabis
This study looks at a sleep-focused treatment to help adults who have ongoing insomnia and also use cannabis regularly. If sleep improves, the trial hopes it may also improve overall outcomes for cannabis use.
Ann Arbor, MichiganAges 21 years+ - NCT05816915Recruiting
Lifestyle changes for fatty liver with metabolic health issues
This trial studies whether a lifestyle program can improve fatty liver disease in people who also have metabolic syndrome (a cluster of health problems like high blood sugar and cholesterol). It may help by improving liver health through diet, activity, and other lifestyle changes.
PragueAges 18 years+ - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+ - NCT05826548Recruiting
Telerehabilitation program for memory, Parkinson’s, and stroke needs
This trial studies a home-based exercise and training program delivered by telerehabilitation (remote care) for people with mild cognitive impairment, Parkinson’s disease, or stroke. It may help improve day-to-day thinking and movement skills by supporting you with structured practice from home.
Lido, VeneziaAges 18–85 - NCT05830903Recruiting
Virtual reality job training for people with schizophrenia
This trial tests a virtual reality (VR) training program to help people with schizophrenia prepare for work. It aims to see whether VR-based job skills training is safe and helpful for improving readiness and functioning.
TaipeiAges 20–40 - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT05851950Recruiting
Group CBT to reduce rumination in psychosis
This trial tests a structured group therapy (rumination-focused CBT) to help reduce repetitive negative thinking (“rumination”) that can worsen symptoms in people with psychosis. It may help you feel less stuck in unhelpful thoughts and improve day-to-day functioning while you continue your usual care.
CopenhagenAges 18–37 - NCT05858346Recruiting
Therapy for social anxiety in Veterans with trauma symptoms
This study compares two kinds of treatment for social anxiety disorder to see which one works better for Veterans. It focuses on people who also have significant posttraumatic stress symptoms (trauma-related symptoms).
Charleston, South CarolinaAges 18–80 - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT05875103Recruiting
Brain and language study using a word fluency task
This study looks at how thinking and language work in people with certain brain conditions, using a simple word-finding task and brain scans. It may help researchers better understand what brain changes are linked to different symptoms.
AmiensAges 18 years+ - NCT05892965Recruiting
Instant-message online therapy for early post-stroke depression
This study tests whether brief online cognitive behavioral therapy (CBT) delivered through instant messages can reduce depression symptoms after a stroke. It may help if your depression started after your stroke and you have mild to moderately severe symptoms.
Hong KongAges 18 years+ - NCT05894967Recruiting
Study on how perceptual learning works in different age groups
This study looks at what helps people improve how they perceive visual information (“perceptual learning”) and what processes are responsible. It includes younger and older adults and mainly needs good vision and no known eye or brain conditions affecting the retina or nerves.
Riverside, CaliforniaAges 18–85 - NCT05895513RecruitingPhase 2
Pimavanserin trial for aggression and social thinking
This Phase 2 trial tests pimavanserin, a medication that may affect brain signals, to see if it can reduce aggression and improve social thinking in people with intermittent explosive disorder (IED) or a history of aggressive behavior. If you qualify, you’ll be screened with medical tests and questionnaires and must meet medication and safety rules to participate.
Columbus, OhioAges 21–55 - NCT05906069Recruiting
Internet CBT program study for OCD patients
This trial studies whether an online version of cognitive behavioral therapy (CBT, a structured talk-therapy approach) helps people with obsessive-compulsive disorder (OCD), and tries to predict who will benefit most. It may help by improving treatment planning and matching therapy to the right person.
Braga, GualtarAges 18–65 - NCT05906407Recruiting
Genetic-guided treatment planning for high-risk early breast cancer
This study uses tumor genetic testing to help plan more precise treatment for people with early high-risk breast cancer. You may be asked to give a recent tumor sample so researchers can match your cancer features with the best available options.
AugsburgAges 18–80 - NCT05915000Recruiting
CSF protein tests to predict shunt response in hydrocephalus
This study looks at fluid-based “CSF” protein markers to predict how well a brain shunt works in adults with chronic hydrocephalus (fluid buildup). If you qualify, your CSF sample may help doctors better estimate your likely response to treatment.
Valencia, ValenciaAges 18 years+ - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT05919485Recruiting
Brain stimulation study for mild cognitive problems in Parkinson’s
This trial tests whether a type of noninvasive brain stimulation (tDCS) can improve thinking and memory in people with mild cognitive impairment in Parkinson’s disease. You may be eligible if you have these diagnoses, are on stable medications, and can safely complete brain scan/testing.
Antalya, AlanyaAges 45–80 - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05925621Recruiting
Registry for early Alzheimer-related memory problems
This study registry collects health and brain-testing information for people with mild cognitive impairment or early Alzheimer’s dementia. It may help researchers better understand early Alzheimer disease and plan future treatments.
Boston, MassachusettsAges 50–95 - NCT05929703Recruiting
Care approach for hospitalized older adults at risk of confusion
This trial tests new ways to help hospitalized older adults (and their family/care partners) stay comfortable and avoid or reduce episodes of acute confusion. It focuses on people who are likely to develop delirium during their hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05931536Recruiting
How diet, stress, and thinking affect the gut
This study looks at how what you eat and your stress level may change thinking and the bacteria in your gut. It may help researchers understand links between lifestyle, brain function, and gut health.
CorkAges 18–50
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 2,028 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.