Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,032 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT04184375Recruiting
Memory training for older adults with bipolar disorder
This study tests whether structured memory and thinking exercises (cognitive stimulation) help older adults with bipolar disorder who have mild to moderate thinking and memory problems. You may be offered guided sessions designed to improve everyday thinking skills while checking safety and fit for the program.
La RochelleAges 65 years+ - NCT04817566Recruiting
Brain stimulation and training for thinking problems after breast cancer
This study tests whether brain stimulation plus cognitive training can improve thinking and memory problems in women after chemotherapy for breast cancer. It may help if you still feel “foggy” or have trouble concentrating months after treatment.
GreifswaldAges 18–65 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT05837845RecruitingPhase 2
MDMA plus therapy versus therapy alone for severe PTSD
This Phase 2 study compares MDMA-assisted Cognitive Processing Therapy (a structured talk-therapy) to Cognitive Processing Therapy alone for Veterans with severe PTSD. It aims to see whether adding MDMA helps reduce PTSD symptoms and improve recovery.
Palo Alto, CaliforniaAges 18 years+ - NCT05954741Recruiting
Rehab program to improve thinking in recent vascular memory problems
This trial tests a structured, multi-part rehabilitation program to help people with early dementia symptoms from vascular or mixed causes. If you qualify, you may be offered the rehab program and compared with another approach to see if thinking and daily function improve.
Montescano, PaviaAges 65–80 - NCT06005844Recruiting
Testing a new scale for thinking and mood problems in cerebellum disorders
This study tests a new questionnaire (CCASS) to screen for cognitive-affective syndrome in people with cerebellar damage. It aims to see if the French version works well to identify thinking and mood changes caused by cerebellar disease.
Mulhouse, Haut-RhinAges 18 years+ - NCT06043765Recruiting
Brain stimulation and memory training for glioma patients
This trial tests a combination of brain stimulation (rTMS) and cognitive strategy training to help improve memory and thinking in people with glioma. If you have a stable brain tumor and notice problems with focus or memory, you may be able to join.
AmsterdamAges 18–80 - NCT06058611Recruiting
Computer brain training vs. fun activities for memory
This study compares two types of brain activities: a computer-based cognitive training program and engaging leisure activities like puzzles or games. The goal is to see which approach better helps memory and thinking skills in older adults with mild cognitive concerns.
Zaragoza, ZaragozaAges 50 years+ - NCT06088212Recruiting
Heart failure treatment to help thinking and memory
This trial tests whether better managing heart failure after a hospital stay can protect against thinking and memory problems. It is for people who have heart failure and have had some cognitive difficulties.
Hobart, TasmaniaAges 18 years+ - NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT06201533Recruiting
Light exercise and thinking activities for memory
This study tests if a program that combines light physical activity with simple mental tasks can help improve memory and thinking in people with mild cognitive impairment (MCI). It is for people who are not already exercising regularly and do not take memory medications.
Chiang MaiAges 60 years+ - NCT06215274Recruiting
Leisure activities and early Alzheimer's study
This trial looks at how engaging in mentally stimulating leisure activities (like puzzles, reading, or games) may affect brain health in people with early memory concerns. Researchers want to understand the brain changes that happen with these activities.
Fuzhou, FujianAges 60 years+ - NCT06403995Recruiting
Online therapy for social anxiety
This trial tests an internet-based cognitive-behavioral therapy program designed to help people with social anxiety. You can participate from home if you have internet access and feel anxious in social situations.
Greenfield Park, QuebecAges 18 years+ - NCT06453746Recruiting
Non-drug program to prevent dementia for mild cognitive impairment
This study tests whether non-drug activities (like exercise, brain games, or lifestyle changes) can help prevent dementia in older adults with mild memory loss. You will take part in a program at the hospital and have regular checkups.
Ho Chi Minh CityAges 60 years+ - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT06650969Recruiting
Early detection of cognitive decline in type 2 diabetes
This study is looking at ways to catch early thinking and memory changes in people with type 2 diabetes. By joining, you may help doctors learn how to spot problems sooner and find better ways to help.
Nanjing, JiangsuAges 45 years+ - NCT06657274Recruiting
Digital brain training for early memory problems
This study tests a smart digital program (app or computer-based) to help with memory, thinking, and daily life in people with early Parkinson's, mild cognitive impairment, or early memory concerns. It uses brain stimulation (TMS) along with cognitive exercises.
Brescia, ITAges 18–85 - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT06728774Recruiting
Cognitive rehab for veterans with depression and memory problems
This trial tests a cognitive rehabilitation program for veterans who have depression (MDD) and are experiencing trouble with memory, attention, or thinking. The goal is to see if the program can improve these cognitive issues.
Portland, OregonAges 18 years+ - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06948903Recruiting
Fibromyalgia, brain sensitivity and thinking
This study looks at how the brain's pain sensitivity (central sensitization) relates to memory and thinking problems in people with fibromyalgia. Participating could help doctors understand and treat these symptoms better.
Istanbul, UskudarAges 18–65 - NCT06964581Recruiting
At-home cognitive training for multiple sclerosis
This study tests a at-home thinking and memory training program for people with multiple sclerosis. It aims to help improve mental skills like memory, attention, and planning through remote sessions.
Verona, veronaAges 18–65
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,032 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.