Clinical trials
Colonic Diseases clinical trials
Below are recruiting colonic diseases clinical trials, each written for real people, not researchers. We’re tracking 40 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222800RecruitingPhase 3
Testing a new drug plus chemo for stage 4 colorectal cancer
This study tests a new experimental drug (PF-08634404) combined with standard chemotherapy for people with stage 4 colorectal cancer who have not yet been treated for their advanced disease. The goal is to see if the combination helps shrink or slow the growth of tumors.
Chandler, ArizonaAges 18 years+ - NCT06271538RecruitingPhase 4
Skal Pro Powder for IBS symptoms
This study tests if Skal Pro Powder, a probiotic, can help relieve symptoms of Irritable Bowel Syndrome (IBS). It is for adults with any type of IBS who haven't used certain other treatments recently.
Kubang Kerian, KelantanAges 18 years+ - NCT07351071Recruiting
Study of Signia circular stapler in left colon and rectal surgery
This study is testing a new circular stapler, called the Signia, used to reconnect the bowel during planned left-sided colon or rectal surgery. It aims to see how well the device works in everyday hospital settings.
New Haven, ConnecticutAges 18 years+ - NCT07450612Recruiting
Blood test and AI for early colorectal cancer detection
This study uses a simple blood test (liquid biopsy) and computer analysis to find early signs of colorectal cancer, precancerous growths, and Lynch syndrome. It aims to improve early detection and monitor for any remaining cancer after treatment.
Milan, LombardyAges 18 years+ - NCT05393609Recruiting
Quality-of-life study during surgery for diverticular disease
This trial studies how people’s quality of life changes around diverticular disease surgery. It may help doctors understand what to expect and how to better support patients before and after surgery.
Randers, Central JutlandAges 18 years+ - NCT05414994Recruiting
Study eye bacteria in healthy and eye disease
This study compares the tiny living organisms (“ocular microbiome,” meaning eye-surface bacteria) in different eye conditions. It may help researchers understand how these eye bacteria relate to diseases and why some people develop problems with vision.
Nashville, TennesseeAges 18 years+ - NCT06288464Recruiting
Fiber in tube feeding to improve gut health
This trial tests adding fiber to liquid food given through a stoma before stoma reversal surgery. The goal is to see if it helps improve the balance of good bacteria in the gut.
Preston, LancashireAges 18 years+ - NCT04920032RecruitingPhase 1
Blood test–guided extra treatment for colon cancer recurrence risk
This Phase 1 study uses a blood test called ctDNA to decide whether and how to adjust treatment in people with colon cancer who still have a small amount of disease left after surgery. If your blood test remains positive, the trial aims to reduce recurrence risk by guiding treatment changes.
Orange, CaliforniaAges 18 years+ - NCT05193162Recruiting
Study of gut microbes using stored pancreatic tissue
This study looks at differences in microbes (tiny organisms) using previously collected pancreatic tissue samples. It may help doctors understand how the microbiome relates to pancreatic diseases like pancreatic cancer.
ShanghaiAges 5–85 - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT03803553RecruitingPhase 3
Testing blood tumor DNA treatment after stage III colon surgery
This trial studies how to find tiny hidden cancer cells after stage III colon cancer surgery using a blood test. If the blood test shows tumor DNA, you may get additional treatment to lower the chance of cancer coming back.
Boston, MassachusettsAges 18 years+ - NCT06655415Recruiting
Study for family members at risk of inflammatory bowel disease
This study follows people who have a parent, sibling, or child with Crohn's disease or ulcerative colitis to help understand why some family members develop the condition. If you are 14 or older and do not already have IBD, you may be able to join.
Boston, MassachusettsAges 14 years+ - NCT04896684Recruiting
Study collecting gut health information from adults’ scans
This study is looking at people who need an intestinal scope (endoscopy) for gut symptoms or bowel conditions like IBS, IBD, or possible colorectal cancer. Your results may help doctors better understand these long-term conditions and improve follow-up care.
ToulouseAges 18–99 - NCT05436054RecruitingPhase 4
Plenvu vs Picoprep bowel prep for colonoscopy
This study compares two bowel-cleansing products (Plenvu and Picoprep) to see which works better and is easier to tolerate before a colonoscopy. It may help patients by improving the chance of a clear exam and reducing unpleasant side effects.
Aalborg, North JutlandAges 18 years+ - NCT06265649Recruiting
Managing diverticulitis without surgery: ward comparison
This trial compares non-operative management for acute left colonic diverticulitis (ALCD) in medical versus surgical wards, to see which setting leads to better outcomes. If you have diverticulitis diagnosed by CT scan and are being treated without immediate surgery, you may be eligible.
Trieste, TSAges 18 years+ - NCT06874036Recruiting
Bowel prep and colonoscopy safety in heart, kidney, or liver disease
This study tests how well people with chronic heart, kidney, or liver disease tolerate bowel preparation and colonoscopy. It aims to ensure the procedure is safe and effective for you.
Hyderabad, TelanganaAges 18–75 - NCT05174169RecruitingPhase 2/Phase 3
Adjuvant colon chemotherapy guided by tumor DNA results
This trial tests whether treatment for colon cancer after surgery can be guided by a blood test that looks for leftover cancer signals (ctDNA). It may help some people choose stronger or different chemo based on whether ctDNA is found after surgery.
Birmingham, AlabamaAges 18 years+ - NCT06165289Enrolling by invitation
Balloon dilation with PRP for Crohn's colon narrowing
This trial tests whether adding a platelet-rich plasma (PRP) injection to the standard balloon dilation procedure can help treat a narrowed section of the colon caused by Crohn's disease. It may offer a way to avoid or delay surgery for some patients.
Guangzhou, GuangdongAges 18 years+ - NCT06287671Recruiting
Colorectal Surgery Tissue Study for Better Understanding of Disease
This study is collecting tissue samples from people having surgery on their colon or rectum to better understand colorectal diseases. It may help researchers learn more about conditions like cancer, polyps, or inflammatory bowel disease.
HillerødAges 18 years+ - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT06287814Recruiting
Blood test to detect leftover cancer DNA in colorectal cancer patients
This study uses a simple blood test (liquid biopsy) to look for tiny bits of tumor DNA remaining after colorectal cancer surgery. It aims to see if the test can help predict whether the cancer will come back, especially in people with stage III cancer who will receive chemotherapy.
Montpellier, HéraultAges 18 years+ - NCT06149585Recruiting
Bacteria changes in gum disease patients getting all dental implants
This study looks at how bacteria in your mouth change when all your teeth are removed and replaced with dental implants. If you have severe gum disease and need all your teeth extracted, joining this trial could help researchers understand your healing process.
Cleveland, OhioAges 21 years+ - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+
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Common questions
- Are there clinical trials for colonic diseases?
- Yes. Clin2 currently lists 40 recruiting colonic diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colonic diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colonic diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.