Clinical trials
Colorectal Cancer (Diagnosis) clinical trials
Below are recruiting colorectal cancer (diagnosis) clinical trials, each written for real people, not researchers. We’re tracking 354 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03787056Recruiting
Blood test marker study in many cancer types
This study measures a blood marker called progastrin (at diagnosis and during treatment) to see how well it predicts response or outcomes. It may help doctors choose or monitor treatment more precisely for several cancer types.
BronAges 18 years+ - NCT01479608Recruiting
Liver transplant for colon or rectal cancer liver spread
This trial studies whether a liver transplant can help people with colon or rectal cancer that has spread to the liver (but not elsewhere). It aims to improve outcomes by removing the diseased liver when the cancer has responded to chemotherapy and can still be controlled.
OsloAges 18 years+ - NCT06293014RecruitingPhase 2
TAS-102 with bevacizumab for colorectal cancer maintenance
This trial tests a combination of two drugs, TAS-102 and bevacizumab, as a follow-up maintenance treatment for people with advanced colorectal cancer. The goal is to see if this treatment can keep the cancer from growing after initial chemotherapy and bevacizumab therapy.
Zhengzhou, HenanAges 18 years+ - NCT06326879Recruiting
Comparing early vs late onset colorectal cancer
This study compares patients diagnosed with colorectal cancer at a younger age (under 50) to those diagnosed later in life. By looking at tissue samples and patient surveys, researchers hope to understand differences in the disease and improve care for all ages.
Rozzano, MIAges 18 years+ - NCT06331988Recruiting
Study of colon cancer, bacteria, and the immune system
This study looks at how bacteria in your gut, your immune system, and colon cancer interact. It aims to understand these connections to improve future treatments.
MilanAges 18–75 - NCT04050345Recruiting
Blood test to spot DNA changes after early colon cancer surgery
This study checks a “cell-free tumor DNA” blood test to see if cancer mutations can predict relapse after surgery for early colorectal cancer. If results look risky, they may help guide closer follow-up and future treatment decisions.
Milton Keynes, BuckinghamshireAges 18 years+ - NCT07830407Recruiting
Personalized chemo response test for colorectal cancer
This study is testing a new lab test called ChemoINTEL that may help predict how well your colorectal cancer will respond to common chemotherapy drugs. The goal is to see if this test can help doctors choose the most effective treatment for you.
Liverpool, MerseysideAges 18 years+ - NCT07829081Recruiting
Watch-and-wait after immunotherapy for early-stage GI cancers
This study looks at whether some patients with early-stage stomach, colon, or rectal cancers that are mismatch repair-deficient (a genetic feature making them more likely to respond to immunotherapy) can safely avoid surgery and instead be monitored closely after treatment with immunotherapy. It aims to confirm if this watch-and-wait approach is as effective and helps patients avoid major operations.
BaselAges 18 years+ - NCT05187338RecruitingPhase 1/Phase 2
Study drugs that target immune checkpoints for solid tumors
This early-phase study tests a combination of three immune “checkpoint” medicines in people with advanced solid cancers. It aims to see how well they work and what side effects occur, including when given through a specific liver-focused treatment in eligible patients.
Guangzhou, GuangdongAges 18–70 - NCT06385418RecruitingPhase 2
Colon chemotherapy for colorectal cancer
This trial tests putting a chemo drug (fluorouracil) directly into the colon through a tube. It's for people with colorectal cancer who are already getting other cancer treatment, to see if adding local chemo helps shrink the main tumor.
Nanjing, JiangsuAges 18–75 - NCT07816263Recruiting
Guaraná supplement for cancer-related fatigue
This trial tests whether a natural supplement called guaraná can help reduce fatigue in people undergoing cancer treatment. Guaraná contains caffeine and other compounds that may boost energy and improve well-being.
Bogotá, Bogota D.C.Ages 18 years+ - NCT07788729Recruiting
Support program for cancer patients and their caregivers
This study tests a program that provides social support and short learning sessions to help cancer patients and their caregivers manage daily life. It aims to improve well-being and care for both patients and their support persons.
Augsburg, BavariaAges 18 years+ - NCT07759921Recruiting
Mindfulness program for couples facing metastatic colorectal cancer
This study tests a mindfulness-based program for couples facing metastatic colorectal cancer. It aims to help reduce distress and improve coping for both patients and their partners.
Aurora, ColoradoAges 18–85 - NCT06452745Recruiting
Early colon cancer detection using a blood test
This study uses a simple blood test to find early signs of colorectal cancer in people who already had a positive stool test. If it works, it could help avoid unnecessary colonoscopies in the future.
Reus, TarragonaAges 50–70 - NCT06663839RecruitingPhase 1
Study of NILK-2301 for advanced colorectal cancer
This trial tests a new drug called NILK-2301 for people with colorectal cancer that has spread or cannot be removed. It is for those who have already tried at least one other treatment and have relatively small tumors.
BarcelonaAges 18 years+ - NCT07675967Recruiting
Blood Cell Changes During Cancer Treatment
This study is for people with solid tumors who are about to start chemotherapy or radiation. It looks at how these treatments affect blood cells and may help doctors understand changes in blood health over time.
Boston, MassachusettsAges 18 years+ - NCT03874026RecruitingPhase 2
Folfiri plus cetuximab for advanced, gene-matched colon cancer
This trial tests whether a combination chemotherapy (Folfiri) plus cetuximab works better for people with stage IV colorectal cancer that has specific tumor gene markers and a specific blood-gene type. It may help you shrink tumors or control the cancer if you match the study’s required lab and health criteria.
NaplesAges 18–75 - NCT07649057Recruiting
Urine Test for Early Colorectal Cancer Detection
This study tests whether a simple urine sample can detect colorectal cancer or precancerous polyps. Researchers want to see if this non-invasive test could help identify people at risk before symptoms develop or catch cancer earlier.
New York, New YorkAges 18 years+ - NCT06612281RecruitingPhase 2
Testing a new screening tool for colorectal cancer in people with negative FIT results
This trial tests a new device called Gixam to see if it can help find colorectal cancer in people who recently had a normal FIT test (a stool test for blood). You may be able to join if you are between 45 and 85 years old and are already scheduled for a routine screening colonoscopy.
Portland, OregonAges 45–85 - NCT07644286RecruitingPhase 2
Pirfenidone and immunotherapy with optional radiation for advanced colorectal cancer
This study tests a combination of three treatments—pirfenidone (an anti-scarring drug), a PD-1 inhibitor (an immunotherapy that helps your immune system fight cancer), and sometimes radiation—for colorectal cancer that has stopped responding to standard treatments. The goal is to see if this combination can slow or shrink your cancer.
Wuhan, HubeiAges 18–75 - NCT07627191RecruitingEarly Phase 1
GLP-1 drug plus standard chemo for first-line advanced cancers
This trial tests whether adding a GLP-1 receptor agonist (a drug used for diabetes and weight loss) to standard chemotherapy can help people with advanced pancreatic, colorectal, or liver cancer. It is for people who have not yet started treatment for their metastatic disease and have a BMI of 25 or higher.
Tucson, ArizonaAges 18–99 - NCT07617610Recruiting
Understanding Treatment Resistance in BRAF-Mutated Colorectal Cancer
This study looks at why some people with a specific type of colorectal cancer (BRAF V600E-mutated) stop responding to targeted drugs over time. Researchers will take small tissue samples before and during your treatment with anti-EGFR antibody and BRAF inhibitor to understand resistance and help improve future treatments.
AarauAges 18 years+ - NCT07579780Recruiting
Nerve Block During Laparoscopic Colorectal Cancer Surgery
This trial tests a pain-relief technique called a nerve block during minimally invasive surgery to remove colorectal cancer. The block numbs nerves in the lower abdomen to potentially reduce pain and improve recovery after surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07576049Enrolling by invitation
Colorectal Cancer Treatment Experience Study
This research study looks at how colorectal cancer patients are treated and their outcomes at a major medical center in Rome. It helps doctors understand what approaches work best for patients like you.
RomaAges Any age
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Common questions
- Are there clinical trials for colorectal cancer (diagnosis)?
- Yes. Clin2 currently lists 354 recruiting colorectal cancer (diagnosis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer (diagnosis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer (diagnosis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.