Clinical trials
Colorectal Cancer Screening clinical trials
Below are recruiting colorectal cancer screening clinical trials, each written for real people, not researchers. We’re tracking 381 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220018Recruiting
Colorectal cancer screening for homeless adults
This study offers free colorectal cancer screening to homeless adults aged 45 to 75 who haven't had recent screening. It aims to find and prevent cancer early in people staying at shelter clinics.
Washington D.C., District of ColumbiaAges 45–75 - NCT07525206RecruitingPhase 3
Combination treatment for advanced colorectal cancer
This trial tests a new drug combination for colorectal cancer that has not responded to other treatments. It compares the new drug with a standard treatment to see which is more effective.
Goodyear, ArizonaAges 18 years+ - NCT04074538Recruiting
Colorectal cancer study to help researchers learn patterns
This study is collecting information from people with newly diagnosed colon or rectal cancer, to better understand the disease and support future research. It may help you and others by improving how colorectal cancer is studied and potentially treated over time.
Hangzhou, ZhejiangAges 18 years+ - NCT05426135Recruiting
AI tool to assess cancer risk and guide care
This study tests an artificial intelligence (AI) system that uses your health information and medical images to better judge cancer risk and support diagnosis and treatment decisions. It may help doctors make more consistent assessments by combining clinical records, imaging, and other lab-style data.
Wuhan, HubeiAges 18–75 - NCT05495776Recruiting
Study checks how often Lynch syndrome happens in colon cancer
This registry study looks at how many people with colon cancer also have Lynch syndrome, an inherited condition that can affect cancer risk. If you enroll, your care team collects basic information from your diagnosis to better estimate how common it is.
MoscowAges 18 years+ - NCT05733000RecruitingPhase 2
CPI-613 plus hydroxychloroquine with chemo for advanced solid tumors
This trial tests a drug called CPI-613 (devimistat) combined with hydroxychloroquine along with either 5-fluorouracil or gemcitabine chemo. It’s for people with advanced cancers that have stopped responding to standard treatments, aiming to shrink tumors and slow cancer growth.
Chicago, IllinoisAges 18 years+ - NCT05985109RecruitingPhase 2
KN 046 plus regorafenib for advanced colorectal cancer
This trial tests a combination of two drugs, KN 046 and regorafenib, in people with a type of advanced colorectal cancer that has not responded to previous treatments. The goal is to see if this combination can help shrink or control the tumor.
BeijingAges 18 years+ - NCT06176885RecruitingPhase 2
Immunotherapy plus chemo and targeted therapy for MSS colorectal cancer
This trial tests adding immunotherapy to standard chemotherapy and targeted therapy for people with metastatic colorectal cancer that is MSS (microsatellite stable) and cannot be removed with surgery. It aims to see if this combination helps shrink tumors and improve outcomes.
Jinhua, ZhejiangAges 18–75 - NCT05485077Recruiting
Study of colorectal cancer screening in adults 40+
This study follows people age 40 and older to see how well colorectal cancer screening works in everyday community care. You may answer risk and follow-up questions over time, and the study looks for any cancer diagnoses that happen outside the study hospitals.
Beijing, Beijing MunicipalityAges 40 years+ - NCT06566755RecruitingPhase 3
New drug combo for a common type of colorectal cancer
This trial tests a combination of a new immunotherapy (cadonilimab) with standard chemotherapy (capecitabine, oxaliplatin) and bevacizumab for people with metastatic colorectal cancer that has a RAS mutation or is located on the right side of the colon. The goal is to see if this combination works better than the current standard of care as a first treatment.
Shenyang, LiaoningAges 18–75 - NCT06184698RecruitingPhase 2
Liposomal irinotecan, chemotherapy, and bevacizumab for advanced colorectal cancer
This trial tests a combination of liposomal irinotecan, two chemotherapy drugs (leucovorin and 5-fluorouracil), and bevacizumab as a second-line treatment for people with colorectal cancer that has spread and cannot be removed by surgery.
Shijiazhuang, HebeiAges 18–75 - NCT06632886Recruiting
AI study to find cancers from your past CT scans
This study uses artificial intelligence to look at CT scans you've already had (without dye) to try and find signs of several types of cancer early. It may help find cancer sooner when it's easier to treat.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07722494RecruitingPhase 3
Investigational drug plus bevacizumab for advanced colorectal cancer
This trial tests a new drug combined with a standard treatment for advanced colorectal cancer that has not responded to earlier therapies. It aims to see if the combination can help slow the cancer's growth.
Wuhan, WuhanAges 18 years+ - NCT06207656RecruitingPhase 2
Targeted therapy for BRAF V600E mutated colorectal cancer
This trial tests if combining three targeted drugs (cetuximab, encorafenib, and binimetinib) before surgery can shrink or control cancer in people with a specific BRAF V600E mutation and a stable (MSS) tumor. It focuses on colorectal cancer that is either already able to be removed or could become removable with treatment.
MadridAges 18 years+ - NCT07693751RecruitingPhase 1/Phase 2
Testing a new drug for advanced colorectal cancer
This trial tests a new drug called SOT109 for people with advanced colorectal cancer that can't be removed by surgery or has spread. The goal is to see if it is safe, how well it works, and how the body handles it.
Houston, TexasAges 18 years+ - NCT06653478Recruiting
Smarter cancer risk assessment using all your medical info
This study is testing a new way to use medical images, records, and other information to better assess cancer risk and guide treatment. It may be a good fit if you have a suspicious spot in your lungs, stomach, or colon, or if you are healthy and want to help with early cancer detection research.
Wuhan, HubeiAges 18–75 - NCT07696793RecruitingPhase 4
Simethicone colonoscopy prep for cancer screening
This trial tests a colonoscopy preparation drink that contains simethicone (a gas-relief ingredient) to see if it works better than standard prep for people who are already scheduled for a screening colonoscopy after a positive stool test. It may help make the procedure more comfortable and effective.
Barcelona, BarcelonaAges 50–69 - NCT06663839RecruitingPhase 1
Study of NILK-2301 for advanced colorectal cancer
This trial tests a new drug called NILK-2301 for people with colorectal cancer that has spread or cannot be removed. It is for those who have already tried at least one other treatment and have relatively small tumors.
BarcelonaAges 18 years+ - NCT07676383Recruiting
Better cancer screening with community precision navigation
This trial tests a program to help people at high risk for certain cancers get the free screening tests they need. It aims to make screening easier by providing personalized guidance in the community.
Huaihua, HunanAges 45–74 - NCT07649057Recruiting
Urine Test for Early Colorectal Cancer Detection
This study tests whether a simple urine sample can detect colorectal cancer or precancerous polyps. Researchers want to see if this non-invasive test could help identify people at risk before symptoms develop or catch cancer earlier.
New York, New YorkAges 18 years+ - NCT06612281RecruitingPhase 2
Testing a new screening tool for colorectal cancer in people with negative FIT results
This trial tests a new device called Gixam to see if it can help find colorectal cancer in people who recently had a normal FIT test (a stool test for blood). You may be able to join if you are between 45 and 85 years old and are already scheduled for a routine screening colonoscopy.
Portland, OregonAges 45–85 - NCT07628998Recruiting
Text Messages to Encourage Colorectal Cancer Screening
This study tests whether reminder text messages help people complete colorectal cancer screening. You would receive SMS messages encouraging you to schedule a screening test if you haven't done so after an initial invitation.
Sabadell, CataloniaAges 50–69 - NCT07627191RecruitingEarly Phase 1
GLP-1 drug plus standard chemo for first-line advanced cancers
This trial tests whether adding a GLP-1 receptor agonist (a drug used for diabetes and weight loss) to standard chemotherapy can help people with advanced pancreatic, colorectal, or liver cancer. It is for people who have not yet started treatment for their metastatic disease and have a BMI of 25 or higher.
Tucson, ArizonaAges 18–99 - NCT07621757Enrolling by invitation
Genetic Risk Testing for Colorectal Cancer Screening
This study looks at how genetic risk information can help decide who needs colorectal cancer screening and when. Researchers want to see if testing for genetic risk factors improves screening decisions for people who haven't had a colonoscopy before.
Evanston, IllinoisAges 45–75
Hear when a new Colorectal Cancer Screening trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Colorectal Cancer Screening trials by city
Studies with a site in or near these metro areas.
Colorectal Cancer Screening trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for colorectal cancer screening?
- Yes. Clin2 currently lists 381 recruiting colorectal cancer screening studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer screening trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer screening trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.