Clinical trials
Lung Cancer Screening clinical trials
Below are recruiting lung cancer screening clinical trials, each written for real people, not researchers. We’re tracking 684 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07509034RecruitingPhase 1
Targeted immune cells for recurrent small cell lung cancer
This trial tests a special immune cell therapy (CAR T cells) that targets a protein called B7-H3 on your cancer cells. It is for people with small cell lung cancer or similar neuroendocrine cancers that have returned or not responded to standard treatments.
Bethesda, MarylandAges 18–120 - NCT07153055RecruitingPhase 1/Phase 2
Lurbinectedin with osimertinib for transformed small cell lung cancer
This trial tests a combination of two drugs—lurbinectedin and osimertinib—for people whose lung cancer started as EGFR-mutated non-small cell lung cancer but has changed into small cell lung cancer. The goal is to see if this combination can help control the cancer.
Indianapolis, IndianaAges 18 years+ - NCT05426135Recruiting
AI tool to assess cancer risk and guide care
This study tests an artificial intelligence (AI) system that uses your health information and medical images to better judge cancer risk and support diagnosis and treatment decisions. It may help doctors make more consistent assessments by combining clinical records, imaging, and other lab-style data.
Wuhan, HubeiAges 18–75 - NCT05494021Recruiting
Lung cancer screening study for higher-risk adults
This study tests whether people at higher risk for lung cancer can be safely screened using regular chest CT scans. You might benefit from closer monitoring, and the study helps doctors learn the best way to catch lung cancer earlier.
Shanghai, Shanghai MunicipalityAges 45–75 - NCT05733000RecruitingPhase 2
CPI-613 plus hydroxychloroquine with chemo for advanced solid tumors
This trial tests a drug called CPI-613 (devimistat) combined with hydroxychloroquine along with either 5-fluorouracil or gemcitabine chemo. It’s for people with advanced cancers that have stopped responding to standard treatments, aiming to shrink tumors and slow cancer growth.
Chicago, IllinoisAges 18 years+ - NCT06126406RecruitingPhase 1
CEA-targeting CAR-T cell therapy for advanced solid tumors
This trial tests a new immune cell therapy (CAR-T) designed to attack cancer cells that make a protein called CEA. It may be an option for people with advanced colorectal, esophageal, gastric, or pancreatic cancer who have already tried at least two standard treatments.
Wuhu, AnhuiAges 18 years+ - NCT07838519Enrolling by invitation
Personalized lung cancer screening for veterans
This study tests a personalized approach to help veterans decide if lung cancer screening is right for them. It aims to improve early detection by considering each person's unique risk factors, such as smoking history, military exposures, and lung health.
Aurora, ColoradoAges 50–80 - NCT03562052Recruiting
Lung cancer screening for high-risk workers and smokers
This study offers lung cancer screening (using scans) for people at high risk due to smoking history and workplace exposure to cancer-causing substances. It aims to find lung cancers earlier and understand who benefits most from regular screening.
BordeauxAges 55–74 - NCT07772895RecruitingPhase 1
Glowing dye to help surgeons see lung cancer during surgery
This trial tests a dye that makes lung cancer cells glow during surgery, helping surgeons remove more of the tumor. It's for people who are already scheduled for lung cancer surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06577883Recruiting
New chest X-ray technique for lung cancer screening
This trial tests a new type of chest X-ray called tomosynthesis to improve lung cancer screening. It looks at people who are getting screened for lung cancer, have a suspicious spot on their lung, or have just been diagnosed—as long as they haven't been treated for lung cancer before.
San Diego, CaliforniaAges 30–85 - NCT07738172RecruitingPhase 3
Osimertinib with or without lung tumor surgery for EGFR-mutated non-small cell lung cancer
This study tests whether adding surgery to remove the main lung tumor improves outcomes for people with stage 4 lung cancer that has a specific EGFR mutation and only limited spread. If you qualify, you will take the targeted drug osimertinib for 12 weeks, and if the tumor responds, you may be randomly assigned to either continue the drug alone or have the main tumor surgically removed and then continue the drug.
Taipei, Taipei CityAges 18 years+ - NCT06632886Recruiting
AI study to find cancers from your past CT scans
This study uses artificial intelligence to look at CT scans you've already had (without dye) to try and find signs of several types of cancer early. It may help find cancer sooner when it's easier to treat.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07716280Recruiting
Text message help for lung cancer screening in safety-net clinics
This study tests if text messages can help people who are at risk for lung cancer get screened. If you are a current or former smoker between 50 and 80 years old, and speak English or Spanish, this may help remind you or guide you to get a lung cancer check.
Salt Lake City, UtahAges 50–80 - NCT07716527Enrolling by invitation
Testing a web tool for lung cancer screening
This study is testing a new website-based tool to help people decide if they should get screened for lung cancer. You may be eligible if you are between 50 and 80 years old and currently smoke or recently quit.
New Brunswick, New JerseyAges 50–80 - NCT07711691Recruiting
Lung cancer screening study for current/former smokers
This study aims to help people who qualify for lung cancer screening actually get screened. It tests a program to remind and support you to schedule a low-dose CT scan.
Anaheim, CaliforniaAges 50–80 - NCT05501665RecruitingPhase 1/Phase 2
Adaptive radiation plus pembrolizumab for stage IV lung cancer
This trial tests a personalized (“adaptive”) radiation plan combined with pembrolizumab, and possibly chemotherapy, for advanced stage IV lung cancer. It aims to improve cancer control while carefully managing side effects, including in patients with certain brain metastases.
Nashville, TennesseeAges 18 years+ - NCT06653478Recruiting
Smarter cancer risk assessment using all your medical info
This study is testing a new way to use medical images, records, and other information to better assess cancer risk and guide treatment. It may be a good fit if you have a suspicious spot in your lungs, stomach, or colon, or if you are healthy and want to help with early cancer detection research.
Wuhan, HubeiAges 18–75 - NCT07682597Recruiting
Improving lung cancer screening in Nevada and Mississippi
This trial tests a new system (QUILS) to help state teams in Mississippi and Nevada improve lung cancer screening. You may join if you are part of a team working on this effort.
Greenville, MississippiAges 18–100 - NCT07682610Recruiting
Improving lung cancer screening in Kentucky clinics
This study works with healthcare teams to improve how lung cancer screening is done. It uses surveys and feedback to find better ways to help patients get screened.
Ashland, KentuckyAges 18–100 - NCT07676383Recruiting
Better cancer screening with community precision navigation
This trial tests a program to help people at high risk for certain cancers get the free screening tests they need. It aims to make screening easier by providing personalized guidance in the community.
Huaihua, HunanAges 45–74 - NCT07639255Recruiting
Improving lung cancer screening in Kentucky
This study wants to see if a quality improvement program called QUILS can help healthcare workers find lung cancer earlier. It uses surveys, feedback, and interviews to improve how lung cancer screening is done.
Ashland, KentuckyAges 18–100 - NCT06690385Recruiting
Lung cancer screening for people with COPD or emphysema
This trial offers a lung cancer screening program using a low-dose CT scan for people who have COPD or emphysema and a history of heavy smoking. The goal is to catch lung cancer early, when it's more treatable.
MadridAges 55–75 - NCT07631624Recruiting
Blood test for lung cancer screening in smokers and former smokers
This study tests whether a simple blood test that detects smoking-related changes in DNA can help identify who should get lung cancer screening. Researchers want to see if this test is better at finding people at risk than current methods.
Antwerp, AntwerpenAges 50 years+ - NCT07630168RecruitingPhase 2
Does infusion timing affect treatment response in solid tumors?
This trial tests whether the time of day you receive your infusion (morning vs. afternoon) affects how well your cancer treatment works. It is for people with advanced lung cancer or head and neck cancer that can be surgically removed.
Chapel Hill, North CarolinaAges 18 years+
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Lung Cancer Screening trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lung cancer screening?
- Yes. Clin2 currently lists 684 recruiting lung cancer screening studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer screening trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer screening trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.