Clinical trials
Colorectal clinical trials
Below are recruiting colorectal clinical trials, each written for real people, not researchers. We’re tracking 1,227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07628998Recruiting
Text Messages to Encourage Colorectal Cancer Screening
This study tests whether reminder text messages help people complete colorectal cancer screening. You would receive SMS messages encouraging you to schedule a screening test if you haven't done so after an initial invitation.
Sabadell, CataloniaAges 50–69 - NCT07644286RecruitingPhase 2
Pirfenidone and immunotherapy with optional radiation for advanced colorectal cancer
This study tests a combination of three treatments—pirfenidone (an anti-scarring drug), a PD-1 inhibitor (an immunotherapy that helps your immune system fight cancer), and sometimes radiation—for colorectal cancer that has stopped responding to standard treatments. The goal is to see if this combination can slow or shrink your cancer.
Wuhan, HubeiAges 18–75 - NCT07649057Recruiting
Urine Test for Early Colorectal Cancer Detection
This study tests whether a simple urine sample can detect colorectal cancer or precancerous polyps. Researchers want to see if this non-invasive test could help identify people at risk before symptoms develop or catch cancer earlier.
New York, New YorkAges 18 years+ - NCT07576049Enrolling by invitation
Colorectal Cancer Treatment Experience Study
This research study looks at how colorectal cancer patients are treated and their outcomes at a major medical center in Rome. It helps doctors understand what approaches work best for patients like you.
RomaAges Any age - NCT07542262Enrolling by invitationPhase 2
Low-dose immunotherapy for advanced colorectal and stomach cancer
This study tests a lower dose of immunotherapy in patients with colorectal or stomach cancer that has spread or cannot be removed by surgery. The cancer must have a specific genetic feature (MSI/dMMR). The goal is to see if this approach works well with fewer side effects.
MoscowAges 18 years+ - NCT07429760Enrolling by invitation
Bowel prep with or without antibiotics for left-sided colon surgery
This study compares two ways to prepare for left-sided colorectal cancer surgery: cleaning the bowel with liquid alone, or cleaning the bowel plus taking oral antibiotics beforehand. The goal is to see if adding antibiotics reduces infections after surgery.
Lahore, Punjab ProvinceAges 18–60 - NCT07380867Enrolling by invitation
New marker test for marking colon tumors before surgery
This trial tests a new marker that glows under special light to help doctors see exactly where a colon tumor is during surgery. It may help make the surgery more precise.
Seoul, SeoulAges 19–80 - NCT07334587Enrolling by invitation
Comparing two chemotherapies for advanced colorectal cancer
This trial compares two chemotherapy drug combinations (FOLFOX-6 and CAPOX) to see which works better and has fewer side effects for people with colorectal cancer that has spread. It may help you and your doctor choose the best treatment option.
Lahore, Punjab ProvinceAges 20–70 - NCT07230795Enrolling by invitation
AI-guided colorectal cancer screening for adults 45-49
This trial tests whether a computer program can help more adults ages 45-49 get screened for colorectal cancer. If you are due for screening and see a Penn Medicine doctor, you may be able to join.
Philadelphia, PennsylvaniaAges 45–49 - NCT06931860Enrolling by invitation
Mailed colon cancer screening test comparison
This trial compares two home colon cancer screening tests, Cologuard and FIT, mailed directly to you. It aims to see which one helps more people complete screening and find the test that works best for you.
La Jolla, CaliforniaAges 45–49 - NCT06885424Enrolling by invitation
Long-term follow-up for A2 Bio gene therapy patients
This study follows up with people who previously received a gene therapy product from A2 Biotherapeutics in an earlier trial. The goal is to monitor their health over time and check for any long-term effects.
Gilbert, ArizonaAges 18 years+ - NCT06729736Enrolling by invitation
Faster recovery after colorectal cancer surgery
This trial is testing a program called ERAS (Enhanced Recovery After Surgery) to help patients recover faster after minimally invasive colorectal cancer surgery. It aims to improve your recovery and reduce hospital stay.
Seoul, SeoulAges 19 years+ - NCT06603519Enrolling by invitation
Can a diet reduce inflammation after a colonoscopy?
This study tests whether a special diet can help reduce inflammation and improve gut health after a colonoscopy. It is for people who are getting a repeat colonoscopy because they've had polyps before.
San Diego, CaliforniaAges 18 years+ - NCT06597955Enrolling by invitation
Colorectal Cancer Screening Decision Aid Study
This study is testing a tool to help people decide about getting screened for colorectal cancer. If you are between 45 and 75, get care at certain health systems (like IU Health), and are due for screening, you may be able to join.
Indianapolis, IndianaAges 18 years+ - NCT06583564Enrolling by invitation
ICG dye during surgery for stage III colorectal cancer
This study tests whether using a special dye during surgery helps people with stage III colorectal cancer stay cancer-free longer. The dye, called indocyanine green (ICG), makes tumors and lymph nodes glow under a special camera, helping surgeons remove them more precisely.
Changning, Shanghai MunicipalityAges 18 years+ - NCT06540027Enrolling by invitation
Minimally invasive surgery for rectal cancer inflammation
This study looks at how different types of surgery (open, laparoscopic, or robotic) affect inflammation throughout the body in people with rectal cancer. It may help doctors understand which approach is gentler on your immune system.
IstanbulAges Any age - NCT06443996Enrolling by invitation
Sleep, mood, and colorectal cancer recovery study
This study looks at how your sleep quality and emotional well-being before surgery might affect your recovery from colorectal cancer. By filling out questionnaires, you help doctors learn whether these factors play a role in the cancer coming back.
ShanghaiAges 18–80 - NCT06434376Enrolling by invitationEarly Phase 1
Personalized immune therapy for ctDNA-positive colorectal cancer
This trial tests a personalized immune therapy (like a custom vaccine) for people with colorectal cancer that has a positive ctDNA MRD test after surgery. It aims to use the body's own immune system to target any remaining cancer cells and prevent the cancer from coming back.
Wenzhou, ZhejiangAges 18–80 - NCT06276140Enrolling by invitation
Iron deficiency anemia and recovery after colorectal cancer surgery
This study looks at how iron deficiency anemia affects recovery after surgery for colorectal cancer. It may help doctors understand if treating this type of anemia before surgery improves outcomes.
KamenitzAges 18 years+ - NCT06191185Enrolling by invitation
Improving colonoscopy follow-up after abnormal FIT
This trial tests a program to help people who had an abnormal FIT stool test follow through with getting a colonoscopy. The goal is to improve cancer screening by providing extra support through a care team and technology.
San Francisco, CaliforniaAges 18 years+ - NCT06090994RecruitingPhase 4
Huaier vs capecitabine to prevent colon cancer return
This study compares two medicines to prevent colorectal cancer from coming back after surgery: a traditional Chinese medicine called Huaier and a standard chemotherapy pill called capecitabine. It is for people with stage 2 colon cancer that was completely removed.
Harbin, HeilongjiangAges 18 years+ - NCT06085560Enrolling by invitation
Choose and use an at-home colorectal cancer screening test
This study helps African American adults choose an at-home colorectal cancer screening test and make a plan to use it. It aims to make screening easier and more convenient for you.
Flint, MichiganAges 45–72 - NCT05877456Enrolling by invitation
Checking a polyp-removal scoring tool for doctors
This study tests and confirms a scoring tool (GPAT) that helps describe how well doctors perform polyp removal during endoscopy. It may help standardize training and assessment, which can improve consistency in care.
Ghent, GentAges 18–100 - NCT04296630Enrolling by invitation
Social media for colorectal cancer screening
This study looks at whether social media messages can encourage people in Ontario to get screened for colorectal cancer. If you use Facebook and are in the right age range, you may be able to take part.
Toronto, OntarioAges 55–64
Hear when a new Colorectal trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for colorectal?
- Yes. Clin2 currently lists 1,227 recruiting colorectal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.