Clinical trials
Combination Therapy clinical trials
Below are recruiting combination therapy clinical trials, each written for real people, not researchers. We’re tracking 879 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06015048RecruitingPhase 1/Phase 2
SHR-A1811 plus other therapies for advanced HER2+ tumors
This trial tests a new medicine called SHR-A1811 combined with other cancer treatments for advanced solid tumors that have HER2 protein or HER2 mutations. It may help people whose cancer has not responded to other treatments.
Hefei, AnhuiAges 18–75 - NCT06690476RecruitingEarly Phase 1
Study of IPM514 for esophageal cancer
This trial tests a new drug called IPM514 for people with a type of esophageal cancer (squamous cell). It aims to find out if the drug is safe and effective. The trial has different groups for those who have had prior treatment and those who will have surgery after treatment.
BeijingAges 18 years+ - NCT07222761RecruitingPhase 3
Comparing new treatments for relapsed multiple myeloma
This trial tests if a new medicine called linvoseltamab, alone or combined with carfilzomib, works better than the usual treatments for people with multiple myeloma that has come back or stopped responding after 1 to 3 prior therapies.
Atlanta, GeorgiaAges 18 years+ - NCT06512207Recruiting
Hormone therapy plus immunotherapy for advanced lung cancer
This trial tests a combination of hormone therapy (androgen deprivation) and an immunotherapy drug (anti-PD-1) for men with advanced lung cancer. It aims to see if this combination slows cancer growth better than standard treatments.
Zhengzhou, HenanAges 60 years+ - NCT05909332RecruitingPhase 3
Tested antivascular drug plus chemo versus chemo alone for TNBC
This Phase 3 trial compares an “anti-blood-vessel” drug added to chemotherapy versus chemotherapy alone for people with stage II–IIIC triple-negative breast cancer that has been completely removed with surgery. The goal is to see if adding the study drug improves outcomes after surgery (adjuvant treatment).
Beijing, Beijing MunicipalityAges 18–70 - NCT06190782RecruitingPhase 3
Local therapy for limited metastatic esophageal cancer
This trial tests whether adding targeted radiation or other local treatments can help people with esophageal cancer that has spread to only a few spots (up to 4) after they've been treated with a PD-1 inhibitor. It aims to control the cancer better and improve outcomes.
ShanghaiAges 18 years+ - NCT07378059Recruiting
Loxoprofen patch for shingles pain
This trial tests if a loxoprofen skin patch (a non-steroidal anti-inflammatory drug) can safely relieve moderate to severe pain from shingles. It may be an option for people who have had shingles rash for less than 90 days.
BeijingAges 18 years+ - NCT06851767Enrolling by invitationPhase 1/Phase 2
Gene therapy for X-linked severe combined immunodeficiency
This study tests a gene therapy to treat X-linked severe combined immunodeficiency (X-SCID) without a stem cell transplant from a matched sibling. It aims to improve immune function and reduce infections using your own stem cells modified to carry the correct gene.
Bethesda, MarylandAges 3–99 - NCT06429579Recruiting
Potts shunt for severe pulmonary hypertension in children
This trial tests a surgery called a Potts shunt for children with severe pulmonary hypertension (high blood pressure in the lungs). It may help children who are still very sick despite standard medications.
Beijing, Beijing MunicipalityAges 6 months–18 years - NCT05973097Recruiting
Oral lichen planus treatment with herbal drug and light therapy
This trial tests whether an herbal medicine (paeoniflorin) combined with photodynamic therapy (a light-based treatment) can treat oral lichen planus. You may be considered if you’re an adult with oral lichen planus and can safely take part in the study.
BeijingAges 18 years+ - NCT07788196RecruitingPhase 2
Adding anti-HER2 therapy after surgery for early-stage gastric cancer
This trial tests whether adding a targeted therapy (anti-HER2) to standard chemotherapy after surgery can improve outcomes for people with early-stage gastric cancer that has high HER2 levels. It aims to see if the combination is more effective than chemotherapy alone.
Xi'an, ShaanxiAges 18 years+ - NCT07744269Recruiting
Hand therapy for early complex regional pain syndrome
This trial compares two hand therapy techniques — contrast baths (alternating warm and cool water) and compression with whirlpool therapy — to see which better eases early-stage complex regional pain syndrome (CRPS) after a hand or wrist injury. If you've had hand or wrist trauma and are still in pain, this study might help you find a treatment that reduces discomfort and improves hand use.
Ankara, YenimahalleAges 18–80 - NCT07408804Recruiting
Lenvatinib alone vs. with chemoembolization for liver cancer
This trial compares the combination of two treatments—chemoembolization (TACE) and lenvatinib—against lenvatinib alone for people with liver cancer that cannot be removed by surgery. It aims to see if the combination works better.
DhakaAges 18–75 - NCT07544784RecruitingPhase 2
AK104 plus radiation for colorectal cancer spread to liver
This study tests a new immunotherapy drug called AK104 combined with radiation therapy and standard chemotherapy for colorectal cancer that has spread to the liver. The goal is to see if adding AK104 and targeted radiation improves treatment outcomes compared to standard therapy alone.
ShanghaiAges 18 years+ - NCT07370402Recruiting
Flurbiprofen patch for shingles pain relief
This trial tests if a flurbiprofen skin patch can reduce pain from shingles (herpes zoster). It may help people with moderate to severe pain who have had the rash for less than 90 days.
BeijingAges 18 years+ - NCT07098741Recruiting
Physical therapy for low back pain and pelvic tilt
This study looks at different physical therapy treatments for people with chronic, non-specific low back pain and a forward-tilted pelvis (anterior pelvic tilt). It aims to find which type of exercise or therapy works best to improve posture and reduce pain.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 20–40 - NCT07014202RecruitingPhase 2
Radiation therapy after chemo-immunotherapy for lung cancer
This trial tests whether giving focused radiation to remaining spots of lung cancer (after standard treatment) can help prevent cancer from growing back. It may be an option if you have had 4-6 cycles of chemo plus immunotherapy and still have a few active spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06718257Recruiting
Chemo with immunotherapy and targeted drugs for bile duct cancer
This trial tests whether adding immunotherapy and targeted therapy to standard chemotherapy can help treat intrahepatic cholangiocarcinoma (a type of bile duct cancer). It is for patients who are starting treatment with one of two specific chemo regimens, possibly combined with the new drugs.
Hangzhou, ZhejiangAges 18 years+ - NCT07600268RecruitingPhase 2
Radiation plus maintenance drugs for advanced pancreatic cancer
This trial tests whether adding a focused radiation treatment (SBRT) to ongoing chemotherapy drugs works better than the drugs alone for pancreatic cancer that has stabilized or shrunk after initial treatment. The goal is to see if this combination approach helps patients live longer.
Jinan, ShandongAges 18–70 - NCT07369739RecruitingPhase 2/Phase 3
Combination therapy for chronic active Epstein-Barr virus disease
This trial tests two drugs, golidocitinib and selinexor, given together to treat chronic active Epstein-Barr virus disease (CAEBVD). The goal is to see if this combination can help control the disease better than current options.
BeijingAges 18–70 - NCT06997900RecruitingPhase 2
Combination of Menopur and Rekovelle for first IVF cycle
This study tests a combination of two fertility medications (Menopur and Rekovelle) to see if they work well together during your first IVF cycle. It may be a good option if you have certain types of infertility and meet the health requirements.
Ottawa, OntarioAges 18–40 - NCT06512597Recruiting
Behavioral therapy for active Crohn's disease
This study tests whether a behavioral therapy program can help people with active Crohn's disease feel better when they start a new biologic medication. You'll get extra support to manage stress and symptoms while you and your doctor adjust your treatment.
New York, New YorkAges 18–65 - NCT07033819RecruitingPhase 2
Fuzuloparib and apatinib before surgery for ovarian cancer
This trial tests a combination of two oral drugs—fuzuloparib (a PARP inhibitor) and apatinib (which blocks blood vessel growth to tumors)—given before surgery for advanced ovarian cancer that cannot be removed right away. It is for people whose tumors have a specific genetic marker (HRD positive) and who have not had prior cancer treatment.
Beijing, Beijing MunicipalityAges 18–70 - NCT07482059RecruitingPhase 1/Phase 2
Combination therapy for advanced liver cancer
This trial tests a combination of treatments for liver cancer that cannot be removed by surgery. It uses a special radiation therapy called Y90 along with other drugs to see if they work better together.
Chengdu, SichuanAges 18–80
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Common questions
- Are there clinical trials for combination therapy?
- Yes. Clin2 currently lists 879 recruiting combination therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a combination therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a combination therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.