Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05333250RecruitingPhase 1/Phase 2
Modafinil to reduce cancer-related fatigue
This trial tests whether modafinil can improve cancer-related fatigue in people with advanced cancer. It may help you feel more able to function day to day by reducing how “worn out” you feel.
Ottawa, OntarioAges 18 years+ - NCT05148494RecruitingPhase 4
Enema versus drink for bowel prep before rectal surgery
This trial compares two bowel-clearing methods—an enema given through the rectum versus an oral (by mouth) mechanical bowel prep—during a specific type of rectal surgery. It aims to find which method works better and is easier or safer for patients.
Halifax, Nova ScotiaAges 18–75 - NCT05133024RecruitingPhase 2
Beetroot juice to help prevent bowel slowdown after colon surgery
This Phase 2 study tests whether drinking beetroot juice can reduce “postoperative ileus,” when the intestines temporarily don’t move normally after colorectal surgery. If it works, it may help you recover bowel function sooner after an elective laparoscopic colon and upper rectum operation.
EdegemAges 18 years+ - NCT04976153RecruitingPhase 3
Stem cell implant to treat fecal urge incontinence
This Phase 3 study tests an implant made from a person’s own muscle-related cells to improve fecal “urge” leakage. It’s for adults whose symptoms haven’t improved enough with usual conservative treatments.
GrazAges 18 years+ - NCT04880876Enrolling by invitationPhase 3
Oral IBS-D medicine trial for kids and teens
This trial tests whether an oral medicine (eluxadoline) can help children and teens with IBS-D, a condition that causes stomach pain and frequent loose stools. It’s a Phase 3 study, meaning it’s designed to confirm benefits and safety.
Corona, CaliforniaAges 6–17 - NCT04699591Recruiting
Domperidone for severe stomach movement problems
This trial looks at whether domperidone can help people ages 12–21 with symptoms from stomach not moving well when usual treatments haven’t worked. It’s designed for cases where other causes have been ruled out and patients are monitored for possible heart and hormone side effects.
Kansas City, MissouriAges 12–21 - NCT04623359Recruiting
Testing a detailed bowel pressure test for hard-to-treat constipation
This study checks whether a “high-resolution manometry” test (a thin tube measuring bowel muscle pressure) helps doctors understand and manage constipation. It’s for adults with long-lasting constipation that has not improved with standard laxatives, and who meet specific safety and colon-testing criteria.
CaenAges 18 years+ - NCT04661215Recruiting
Testing stomach opening muscle problems in people with gastroparesis
This study looks at whether abnormal function of the pyloric “stomach outlet” muscle is linked to gastroparesis symptoms (slow stomach emptying). It may help researchers better understand what causes symptoms and guide future treatments.
Scottsdale, ArizonaAges 18–85 - NCT04113382RecruitingPhase 1/Phase 2
A bowel prep study for children having a colonoscopy
This trial tests a bowel-cleansing liquid called CLENPIQ in children ages 1 to 9 who need a colonoscopy. It aims to see if it works well and is safe for preparing the colon before the procedure.
Mobile, AlabamaAges 1–8 - NCT04041713RecruitingPhase 2
Antioxidant drink trial for children with Rett syndrome
This Phase 2 trial studies whether an antioxidant “cocktail” helps children and teens with Rett syndrome compared with a placebo (inactive drink). If you join, you’ll get study assessments and blood tests to see if the treatment is safe and helpful.
Toronto, OntarioAges 2–21 - NCT03720613Recruiting
Testing medicines to prevent heart events in opioid constipation
This study looks at how well naldemedine (and certain other constipation medicines) lower the risk of major heart problems in people who take opioids for constipation. It compares medicine use patterns in people with opioid-induced constipation to see who has fewer serious heart events.
Wilmington, DelawareAges 18 years+
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 155 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.