Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05961059RecruitingPhase 1
Shigella vaccine safety study for healthy adults
This Phase 1 study tests a Shigella (gut infection) vaccine and additives to see how safe they are in healthy adults. If you qualify, you may help researchers understand whether the vaccine triggers any unwanted immune or stomach side effects.
LeidenAges 18–50 - NCT07655115RecruitingPhase 3
Arbaclofen for Autism: Brain Wave Study
This study tests a medicine called arbaclofen to see how it affects brain waves in people with autism. It includes a brief double-blind crossover phase followed by a 10-week open-label treatment period.
ParisAges birth–64 years - NCT07621367Recruiting
Gut oxygen therapy for bowel problems from low oxygen
This trial tests a treatment that delivers oxygen directly to the gut through a small tube. It is for people with long-term heart failure or sleep apnea who also have belly pain, bloating, constipation, or diarrhea.
Nanjing, JiangsuAges 18 years+ - NCT07607249Enrolling by invitation
Floating Needle Treatment for Stomach Issues After Knee Surgery
This trial tests whether a traditional Chinese acupuncture technique called 'floating needle' can help with stomach and bowel problems that sometimes happen after knee surgery under general anesthesia. You would receive this treatment along with standard post-surgery care to see if it reduces nausea, constipation, or other digestive issues.
Guangzhou, GuangdongAges 18 years+ - NCT07587866Recruiting
Panuri Test for Suspected Pancreatic Cancer
This study tests a new diagnostic tool called Panuri to help detect pancreatic cancer in adults who have symptoms suggesting the disease. The test may help doctors identify pancreatic cancer earlier and more accurately.
BékéscsabaAges 18 years+ - NCT07577661RecruitingPhase 1/Phase 2
Electrical and medication combination therapy for sleep apnea
This trial tests whether combining electrical stimulation (via an Inspire device you already have or will get) with two medications can better treat obstructive sleep apnea. You'll help researchers understand if this combination works better than the device alone.
Boston, MassachusettsAges 18–79 - NCT07583342Enrolling by invitationPhase 4
RELiZORB for feeding problems in severe pancreatitis
This study tests whether a medication called RELiZORB can help adults with moderate to severe acute pancreatitis (sudden, severe pancreas inflammation) tolerate nutrition delivered through a feeding tube. If your body is struggling to accept enough nutrition during acute pancreatitis, this trial may help you receive adequate nutrition while you recover.
Bay Shore, New YorkAges 18 years+ - NCT06730451Recruiting
Fecal transplant for gut health after organ transplant
This trial tests whether fecal microbiota transplantation (Washed Microbiota Transplantation, or WMT) can help people who have gut problems like diarrhea, constipation, or infection after receiving a solid organ transplant. It aims to restore healthy gut bacteria.
Nanjing, JiangsuAges Any age - NCT07545772RecruitingPhase 2
Testing Brenipatide for Constipation-Focused IBS
This trial tests a new medicine called brenipatide to see if it can help people with IBS-C (irritable bowel syndrome with constipation). The study focuses on whether the drug reduces belly pain and improves bowel movements in people whose main symptom is hard or infrequent stools.
Mesa, ArizonaAges 18–75 - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75 - NCT07540312Recruiting
Compression System for Moderate to Severe Irritable Bowel Syndrome
This trial tests a wearable compression device designed to help people with moderate to severe irritable bowel syndrome (IBS). The device applies variable pressure to the abdomen and may help reduce symptoms like abdominal pain, bloating, and bowel irregularities.
Kissimmee, FloridaAges 18–60 - NCT07519564RecruitingPhase 1
Study of GB18 Injection for Cancer-Related Weight Loss
This Phase 1 trial tests a new drug called GB18 to help cancer patients who have experienced significant weight loss and muscle wasting—a condition called cancer cachexia. The drug works by targeting a specific protein involved in weight loss, and researchers want to learn if it can help patients regain weight and strength while also being safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05801380Recruiting
Tracking how well a medicine works in Alzheimer’s patients
This study looks at how effective a treatment is in people newly diagnosed with mild to moderate Alzheimer’s disease. It also involves health and medication history checks and likely stool (fecal) sample collection to monitor effects.
Manila, National Capital RegionAges 65 years+ - NCT07494968Recruiting
Finding ways to track diet compliance in IBS patients
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Ann Arbor, MichiganAges 18–65 - NCT07488442Recruiting
Cognitive behavioral therapy for chronic constipation
This trial tests if cognitive behavioral therapy can help people with a specific type of chronic constipation called dyssynergic defecation. If you have had constipation for over a year and meet some specific tests, this therapy might improve your symptoms.
Ankara, YenimahalleAges 18–55 - NCT07482696Recruiting
Biofeedback training for pelvic floor muscle issues in constipation
This trial tests whether electromyographic biofeedback therapy can help people who have trouble relaxing their pelvic floor muscles during bowel movements, a condition called dyssynergic defecation. It may improve chronic constipation and hard stools.
Kocaeli, IzmitAges 18–70 - NCT07473713RecruitingPhase 1
Veverimer for bone loss in adults with osteopenia
This study tests whether a medication called veverimer can help reduce bone loss in adults with osteopenia (early bone thinning) by lowering the acid load from their diet. Participants must be 50 or older, eat a typical Western diet, and have low bone density but not full osteoporosis.
Boston, MassachusettsAges 50 years+ - NCT07450443RecruitingPhase 2/Phase 3
Gut health and autism: a study on the gut barrier and bacteria
This trial is looking at the connection between the gut and autism. It tests whether certain gut bacteria and the gut's protective barrier are different in children with autism and gastrointestinal issues. This could help find new ways to improve symptoms.
Milan, MIAges 3–8 - NCT07450547RecruitingPhase 2
A trial of a new medicine for cystic fibrosis and pancreatic problems
This trial tests a new medicine (ANG003) for people with cystic fibrosis who have severe pancreatic problems. It looks at how safe and effective the medicine is, and whether it helps with digestion.
Long Beach, CaliforniaAges 12 years+ - NCT07444008Recruiting
BioAmicus Complete for infant digestive and skin issues
This study tests if BioAmicus Complete, a probiotic blend, can help babies with colic, reflux, diarrhea or constipation, and food allergy-related skin problems. Eligible babies are 1 to 4.5 months old, breastfed or formula-fed, and whose parents speak Russian.
Saint PetersburgAges 1 month–5 months - NCT07435740Recruiting
Online sleep coaching for parents of autistic children
This study tests a telehealth program where parents learn techniques to help their young child with autism fall asleep and stay asleep. The goal is to improve the child's sleep without needing medication.
Cleveland, OhioAges 3–7 - NCT06801938Recruiting
Blue dye test during incontinence surgery to reduce complications
This study tests if using a special blue dye (methylene blue) during surgery to correct stress urinary incontinence helps doctors find and prevent complications. It compares two surgical methods (TVT and TOT) to see which is safer.
IstanbulAges 18–85 - NCT07420231Recruiting
Prebiotic and Postbiotic for Digestive Comfort
This trial tests whether taking a prebiotic and a postbiotic together can help reduce intestinal discomfort such as bloating, gas, or stomach pain. If you have ongoing mild to moderate digestive symptoms, this study may offer a new approach to feeling better.
Louvain-la-Neuve, Brabant WallonAges 18–75 - NCT07424898Enrolling by invitation
Lactose Intolerance and Gut Health Study
This study looks at how lactose intolerance is linked to gut health. It is for adults with ongoing digestive issues like bloating, pain, or diarrhea, to see if their gut lining may be more sensitive.
IstanbulAges 18–70
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 155 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.