Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06825260RecruitingPhase 4
PEG3350 vs Senna after urogynecologic surgery
This study compares two common laxatives to see which works better for preventing constipation after surgery for pelvic organ prolapse or stress urinary incontinence. It will help find the best way to keep you comfortable during recovery.
Syracuse, New YorkAges 18 years+ - NCT06738550Enrolling by invitation
Agave inulin for constipation in new dialysis patients
This study tests whether a natural fiber supplement called agave inulin can help with constipation and improve quality of life for people who have just started peritoneal dialysis for kidney failure.
Metepec, State of MexicoAges 18 years+ - NCT03687814Recruiting
Low FODMAP diet plus PEG for IBS with constipation
This study tests whether a low-FODMAP diet combined with PEG 3350 can reduce symptoms in adults with IBS-C (irritable bowel syndrome with constipation). It may help improve bowel habits and abdominal pain, and it checks which people can safely follow the diet and treatment plan.
Ann Arbor, MichiganAges 18 years+ - NCT07276932Recruiting
Acupoint paste for constipation after chemo
This study tests whether applying a special paste to acupoints (specific points on your body) can help relieve constipation and boost energy (qi) in people with colorectal cancer who've had chemotherapy. It's for patients who feel weak and have trouble with constipation after treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT07093463Recruiting
Colon-delivered Vitamin B2 for Gut Health
This trial tests whether a special form of vitamin B2 (riboflavin) delivered to the colon can improve gut health in people with mild to moderate bowel complaints. The study compares the effects of this supplement to a standard diet add-on (inulin) and looks at changes in gut bacteria and symptoms.
Berlin, State of BerlinAges 50–70 - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Foley, AlabamaAges 6–18 - NCT07007468Recruiting
Preventing constipation in cancer patients on chemo
This trial tests a way to prevent constipation caused by chemotherapy for breast or lung cancer. It may help if you have hard, difficult-to-pass stools (Bristol type 1 or 2) within five days of treatment.
Istanbul, MarmaraAges 18 years+ - NCT06833684Recruiting
Comparing MOWOOT and trans-anal irrigation for constipation
This study tests two treatments for chronic constipation: a device called MOWOOT (which uses gentle abdominal massage) and trans-anal irrigation (a way to wash out the rectum). It is for people who have tried biofeedback therapy and still need help managing their constipation.
London, LondonAges 18 years+ - NCT06937814Recruiting
Effect of Humiome Post LB on Gut Comfort in Healthy Adults
This study tests a supplement called Humiome Post LB to see if it helps with mild digestive discomfort like bloating, irregular stools, and urgency. If you have frequent but not severe bowel issues (10-20 movements per week with loose stools) and are generally healthy, this may be for you.
London, OntarioAges 18–75 - NCT06730451Recruiting
Fecal transplant for gut health after organ transplant
This trial tests whether fecal microbiota transplantation (Washed Microbiota Transplantation, or WMT) can help people who have gut problems like diarrhea, constipation, or infection after receiving a solid organ transplant. It aims to restore healthy gut bacteria.
Nanjing, JiangsuAges Any age - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT06198309Recruiting
Predicting worsening COPD in severe patients
This study builds a tool to predict which COPD patients are likely to have worsening symptoms. It may help your doctor better manage your care if you have severe COPD.
Beijing, Beijing MunicipalityAges 40–85 - NCT07587866Recruiting
Panuri Test for Suspected Pancreatic Cancer
This study tests a new diagnostic tool called Panuri to help detect pancreatic cancer in adults who have symptoms suggesting the disease. The test may help doctors identify pancreatic cancer earlier and more accurately.
BékéscsabaAges 18 years+ - NCT07039448Recruiting
Acupressure for constipation in adults with mental illness
This trial tests if learning and practicing acupressure on yourself can help relieve constipation in adults who are staying in a psychiatric hospital. You would receive training and practice at home for four weeks.
Tuenmen, New TerritoriesAges 18 years+ - NCT07488442Recruiting
Cognitive behavioral therapy for chronic constipation
This trial tests if cognitive behavioral therapy can help people with a specific type of chronic constipation called dyssynergic defecation. If you have had constipation for over a year and meet some specific tests, this therapy might improve your symptoms.
Ankara, YenimahalleAges 18–55 - NCT07621367Recruiting
Gut oxygen therapy for bowel problems from low oxygen
This trial tests a treatment that delivers oxygen directly to the gut through a small tube. It is for people with long-term heart failure or sleep apnea who also have belly pain, bloating, constipation, or diarrhea.
Nanjing, JiangsuAges 18 years+ - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT07736144Recruiting
Herbal formula study for fibromyalgia pain relief
This study tests a Chinese herbal formula called Yangyin Roujin (which nourishes yin and softens the muscles) to see if it helps reduce pain and other symptoms of fibromyalgia. If you have fibromyalgia and a pain level of 4 or more, you may be able to join.
Beijing, Beijing MunicipalityAges 18–75 - NCT07732894Recruiting
Exercise and Guided Imagery for Bowel Symptoms After Cancer Surgery
This study tests if combining gentle aerobic exercise with guided imagery (a relaxation technique using your imagination) can help improve bowel control and reduce symptoms after rectal cancer surgery.
IstanbulAges 18–65 - NCT05588323RecruitingPhase 1/Phase 2
Testing naldemedine for constipation caused by opioid pain meds
This study tests whether naldemedine is safe and how the body processes it in children who take opioid medicines and are dealing with constipation or are at risk for it. It may help some children by reducing constipation side effects from opioid pain treatment.
TiranaAges 2–18 - NCT07355062RecruitingPhase 3
Testing Veverimer for metabolic acidosis in kidney disease
This study tests an oral medicine called Veverimer to see if it safely corrects low bicarbonate levels (metabolic acidosis) in people with chronic kidney disease. It might help you feel better and protect your kidneys.
Chula Vista, CaliforniaAges 18 years+ - NCT06951698RecruitingPhase 3
Testing KarXT for bipolar I mania
This trial tests a new medicine, KarXT, to see if it can safely treat manic episodes in people with bipolar I disorder. It is for patients who are currently hospitalized for a manic episode that started within the last 3 weeks.
Bentonville, ArkansasAges 18–65 - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT05333250RecruitingPhase 1/Phase 2
Modafinil to reduce cancer-related fatigue
This trial tests whether modafinil can improve cancer-related fatigue in people with advanced cancer. It may help you feel more able to function day to day by reducing how “worn out” you feel.
Ottawa, OntarioAges 18 years+
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 153 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.