Clinical trials
Control clinical trials
Below are recruiting control clinical trials, each written for real people, not researchers. We’re tracking 2,964 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42 - NCT04514445Recruiting
Study of genes in people with bicuspid aortic valve
This study looks for genetic (inherited) differences that may be linked to bicuspid aortic valve (BAV). It includes people with BAV and close family members to help understand why BAV happens and whether genes play a role.
KetteringAges 10–99 - NCT04529031Recruiting
Study of reminder-based positive thinking for teens with PTSD
This study looks at whether a “reminder-focused positive thinking” approach can help teens with PTSD. It may benefit you by testing how certain cues and supportive thoughts affect PTSD symptoms and related wellbeing.
Los Angeles, CaliforniaAges 11–15 - NCT04429607Enrolling by invitationPhase 2
Testing different lasers for facial oil gland overgrowth
This study compares two types of laser treatments to see which works best for sebaceous hyperplasia (enlarged oil glands that can cause small bumps on the skin). If you are an adult getting cosmetic treatment for this condition, your results and possible side effects may help guide better future care.
Chicago, IllinoisAges 18 years+ - NCT04430426Enrolling by invitation
Study for kidney stone patients with an AGXT gene change
This study looks at people age 18+ who have a history of calcium oxalate kidney stones and who have a specific AGXT gene change found on genetic testing. It involves following a controlled diet for five days, which may help researchers understand how diet affects kidney stones in this group.
Birmingham, AlabamaAges 18 years+ - NCT04427241RecruitingPhase 4
Testing Cerebrolysin for prolonged brain injury after bleeding stroke
This study tests whether Cerebrolysin can improve recovery in people who remain in a vegetative or minimally conscious state more than 4 weeks after a bleeding stroke. It also tracks safety, to make sure the treatment is not causing harmful side effects.
SeoulAges 19–120 - NCT04472702Recruiting
Ultrasound vs X-ray guidance for knee pain ablation
This trial compares two ways (ultrasound or X-ray guidance) to place a treatment for painful knee arthritis. It aims to see whether one guidance method works as well as the other for reducing knee pain.
Sacramento, CaliforniaAges 35–99 - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT04275726Recruiting
Myval heart valve study for adults needing TAVI
This trial studies whether the Myval THV (a new heart valve) is safe and effective for adults who need TAVI, a procedure to replace a narrowed heart valve without open-heart surgery. You may be considered if a heart team says you’re a good candidate for this valve procedure and you’re willing to join the study.
MinskAges 18 years+ - NCT04260854Enrolling by invitationPhase 1
Bupivacaine for pain control during skin surgery
This Phase 1 study tests bupivacaine, a numbing medicine, to see how well it controls pain during cutaneous (skin) surgery. It’s primarily looking at safety and how the medicine works for people undergoing the procedure.
Chicago, IllinoisAges 19 years+ - NCT04284397RecruitingEarly Phase 1
Study of safe temperature conditions for adults
This early study looks at which hot or cold environments are safest and most challenging for adults who don’t have symptoms of disease. It may help improve safety guidelines so older adults can exercise or be exposed to temperature changes more safely.
University Park, PennsylvaniaAges 18 years+ - NCT04333706RecruitingPhase 1/Phase 2
Sarilumab plus capecitabine for certain breast cancers
This trial studies whether adding sarilumab to capecitabine can shrink or control metastatic or high-risk breast cancer that lacks HER2 and is either triple-negative or hormone-resistant. It aims to find a safe dose first, then look at how well the treatment works compared with historical results.
Los Angeles, CaliforniaAges 18–99 - NCT04300998Recruiting
CAR-T therapy study for older adults
This study looks at how well CAR-T cell therapy works and how safely it can be given to older adults. It is for people whose cancer or related blood condition has come back or did not respond, and who are receiving a standard (commercial) CAR-T product.
New York, New YorkAges 60 years+ - NCT03042988Recruiting
Heat stress test in people with low nerve control and high blood pressure
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
Nashville, TennesseeAges 18–80 - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04246138Recruiting
Robot-assisted knee replacement alignment: best function
This trial compares two types of robot-guided knee replacement alignment to see which one helps people do everyday activities better after surgery. If you have “wear-and-tear” knee arthritis, you may be offered one of the two surgical alignment approaches as part of a study.
Hull, East YorkshireAges 18–90 - NCT04226716Recruiting
Studying pelvic pain causes in multiple or first pregnancies
This study looks at why pelvic girdle pain happens during pregnancy, focusing on body sensing (proprioception), stress factors, and inflammation. You may be able to help researchers understand the causes and who is most at risk.
HasseltAges 18–40 - NCT04234971RecruitingPhase 4
Compare costs of bone grafting for cleft jaw repair
This study looks at whether alveolar bone graft surgery is cost-effective for people with cleft lip and palate. It may help clinics choose the most practical approach for the best outcomes while managing overall costs.
Houston, TexasAges 6–15 - NCT04227314RecruitingPhase 3
Apremilast vs placebo for severe recurrent mouth ulcers
This Phase 3 trial tests whether apremilast can reduce severe, recurring mouth ulcers compared with an inactive placebo. It aims to improve ulcer frequency and pain while carefully checking safety.
AmiensAges 18 years+ - NCT04237623RecruitingPhase 2
GM-CSF after transplant using a matched related donor
This Phase 2 study tests whether giving a medicine called GM-CSF after an allogeneic transplant (using a matched related donor) can improve outcomes. Participants must meet health and donor-matching requirements and be eligible to safely receive the treatment and consent to the study.
Atlanta, GeorgiaAges 18–78 - NCT04213547Recruiting
Sleep and blood sugar control in teens with type 2 diabetes
This study looks at how sleep timing and length relate to blood sugar control in teens with type 2 diabetes. It also checks whether teens who meet certain sleep and blood-sugar targets—and can follow sleep tracking—can take part in the study and feedback sessions.
Philadelphia, PennsylvaniaAges 12–20 - NCT04243356Enrolling by invitation
ICU nurse involvement in a post-ICU follow-up clinic
This study looks at whether having ICU nurses actively involved in a follow-up clinic after ICU discharge improves patients’ recovery and follow-up care. It focuses on patients who were cared for in the ICU and the registered nurses who cared for them.
Ann Arbor, MichiganAges 18 years+ - NCT04170244Recruiting
Skin microbiome study in atopic dermatitis and psoriasis
This study looks at the skin’s germs (“microbiome”) in people with atopic dermatitis (eczema) or psoriasis. It may help researchers better understand what’s going on on the skin and how that might relate to disease severity.
Rochester, New YorkAges 13 years+ - NCT04212780Recruiting
Testing a smarter DBS system for severe essential tremor
This trial tests an upgraded deep brain stimulation (DBS) system that can “sense” tremor and adjust treatment in a loop. It’s designed for people with severe essential tremor whose tremor is still disabling despite standard DBS and medication.
Gainesville, FloridaAges 21–99
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Common questions
- Are there clinical trials for control?
- Yes. Clin2 currently lists 2,964 recruiting control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.