Clinical trials · California
Coronary Arterial Disease (CAD) clinical trials in California
We’re tracking 15 recruiting coronary arterial disease (cad) studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Los Angeles, CaliforniaAges 18–80 - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Los Angeles, CaliforniaAges 30–60 - NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
La Jolla, CaliforniaAges 18 years+ - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Santa Barbara, CaliforniaAges Any age - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
La Jolla, CaliforniaAges 18 years+ - NCT06399692RecruitingPhase 3
Choosing heart bypass or stents for women with heart disease
This study compares two common procedures to improve blood flow to the heart in women with blockages in multiple heart arteries. It aims to find which approach works better for women and may help guide future treatment decisions.
Glendale, CaliforniaAges 18 years+ - NCT06399705RecruitingPhase 3
Comparing bypass surgery versus stenting for Black and Hispanic patients with coronary artery disease
This study compares two common ways to treat blocked heart arteries: bypass surgery and stenting. It aims to find which works better for Black and Hispanic patients with multiple blockages.
Glendale, CaliforniaAges 18 years+ - NCT06164730RecruitingPhase 1
Study of VERVE-102 for high cholesterol or early heart disease
This trial tests a new medicine called VERVE-102 for people with a specific type of high cholesterol (HeFH) or early coronary artery disease. It aims to see if it can help lower cholesterol levels.
Pomona, CaliforniaAges 18–70 - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT01517425Enrolling by invitation
Using blood stem cells to study heart disease traits
This study uses your blood to create special lab cells (induced pluripotent stem cells) to better understand heart-related differences between people with coronary artery disease and generally healthy older adults. It may help researchers learn what biological traits are linked to heart risk and how those traits work.
La Jolla, CaliforniaAges 18 years+ - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT06653387Recruiting
Testing a new carotid stent with blood-flow reversal for high-risk patients
This trial tests a new carotid stent system used with a special blood-flow reversal device to treat blocked carotid arteries. It is for people with high-risk conditions who might not be good candidates for traditional open surgery, and aims to see if the stent is safe and effective in preventing strokes.
Sacramento, CaliforniaAges 18–79 - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting coronary arterial disease (cad) studies listed above.
- Adventist Health Glendale · 2 studies
- Cedars-Sinai Women's Heart Center · 2 studies
- University of California, San Francisco · 2 studies
- Abcentra Investigational Site
- Biopharma Informatic LLC
- Cedars - Sinai Medical Center
- Cedars-Sinai Medical Center
- Clinical Study Center
What taking part in a coronary arterial disease (cad) study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Coronary Arterial Disease (CAD) trials in other states
Common questions
- Are there coronary arterial disease (cad) clinical trials in California?
- Yes. We're currently tracking 15 recruiting coronary arterial disease (cad) studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a coronary arterial disease (cad) study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a coronary arterial disease (cad) trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New coronary arterial disease (cad) studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.