Clinical trials
COVID-19 Infection clinical trials
Below are recruiting covid-19 infection clinical trials, each written for real people, not researchers. We’re tracking 195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07397455RecruitingPhase 1
COVID-19 Omicron Human Challenge Study
This study is a 'human challenge' trial where healthy volunteers who have been vaccinated and have low antibody levels are deliberately exposed to a newer Omicron variant of COVID-19. The goal is to learn how the virus spreads and how to test treatments or vaccines.
LondonAges 18–50 - NCT04392401Recruiting
Study immune changes in adults during ICU stay for COVID-19
This study looks at how your immune system responds while you’re in the intensive care unit (ICU) for COVID-19. Researchers will collect samples early in the ICU stay to better understand immune changes during the illness.
BronAges 18 years+ - NCT05566483Recruiting
Study long COVID physiology and cardiopulmonary rehab effects
This study looks at how long COVID affects the body and whether cardiopulmonary rehabilitation improves quality of life and physical function. It may help participants better understand their symptoms and see if a structured rehab program improves daily abilities.
Aurora, ColoradoAges 18 years+ - NCT06517706Recruiting
Studying brain health after COVID-19
This study looks at how COVID-19 affects thinking and memory. It aims to understand and help people who still have brain fog or other cognitive issues after their infection.
Nicosia, CyprusAges 25–60 - NCT00571389Recruiting
Collecting blood cells from people with cancer or COVID-19
This study collects blood cells using a special blood-draw procedure called leukapheresis (for some participants) and other samples. It aims to better understand cancer and immune-related cells, which may help researchers design or improve future treatments.
Huntersville, North CarolinaAges 5 years+ - NCT04652115RecruitingPhase 2
Defibrotide for severe COVID-19 in adults
This trial tests defibrotide to see if it improves outcomes in people hospitalized with severe COVID-19. You may be considered if you have confirmed infection, abnormal chest imaging, and meet specific severity and safety requirements.
Boston, MassachusettsAges 18–100 - NCT04381936RecruitingPhase 3
Testing COVID-19 or pneumonia treatments in hospitalized patients
This trial tests different treatments for serious lung infections in people who are already in the hospital. It may help doctors learn which treatment works best for recovery and survival when pneumonia-like illness is suspected.
BrusselsAges birth+ - NCT04424992Recruiting
Observing hospitalized adults with COVID-19 lung infection
This study follows adults who are hospitalized with COVID-19 in the lungs. The goal is to better understand how COVID-19 behaves in the hospital over time.
MonzaAges 18 years+ - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT04586413Recruiting
Help build and study a quality-of-life tool after COVID-19
This study will collect information from adults who had COVID-19 (confirmed by a test or diagnosis) to develop and improve a questionnaire about life after infection. Your answers may help researchers better track symptoms and quality of life over time.
OxfordAges 18 years+ - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT04896606RecruitingPhase 1/Phase 2
Matched donor immune therapy for mild to moderate COVID-19
This early-phase study tests immune cells from a matched family donor (made to target the COVID-19 virus) to see if they can help people with mild-to-moderate COVID-19 who are hospitalized and at higher risk for getting sicker. It aims to check safety first and also look for signs of benefit.
Valhalla, New YorkAges 18–65 - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Decatur, GeorgiaAges 18–64 - NCT04959734Recruiting
Study of COVID-19 effects on emergency visits for infant lung infections
This study looks at how the COVID-19 era changed emergency department visits for young children with breathing problems, such as bronchiolitis or first-time viral wheeze. It may help doctors understand trends in these illnesses and plan better care during outbreaks.
LeicesterAges birth–2 years - NCT05266222Recruiting
Collecting respiratory virus samples for a research library
This study collects samples from people who have or might have a cold/respiratory virus, then stores them for future research. It may help researchers better understand respiratory germs and develop better treatments.
Bethesda, MarylandAges 3 years+ - NCT05534009Recruiting
Study of healthcare workers’ COVID infection and vaccine history
This study gathers information about healthcare workers (adults) and tracks your past COVID-19 infection and vaccination history. It may help researchers understand how COVID affects healthcare workers and how vaccines relate to infection outcomes.
DüsseldorfAges 18 years+ - NCT06491966Recruiting
Comparing immune responses in bacterial vs. COVID-19 sepsis
This study compares how the body's immune system responds to bacterial sepsis vs. viral sepsis (COVID-19) in intensive care unit patients. The goal is to find better ways to treat each type of life-threatening infection.
Chengdu, SichuanAges 18–90 - NCT06585241RecruitingPhase 4
Study of Updated COVID-19 Vaccines for High-Risk Groups
This trial tests updated COVID-19 vaccines designed to better protect against current variants. It's for people who have already been vaccinated and are at higher risk for severe COVID-19.
Atlanta, GeorgiaAges 6 months+ - NCT06693362RecruitingPhase 1
Stem cell therapy for severe viral pneumonia
This trial tests whether injecting stem cells from the womb's blood supply can help treat severe viral pneumonia. It aims to improve recovery for people who are very sick and need hospital care.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06821126RecruitingPhase 1/Phase 2
Nasal spray COVID-19 vaccine booster study for healthy adults
This study tests a new nasal spray COVID-19 vaccine to see how it compares to an mRNA booster shot. It is for healthy adults who have already had at least 3 doses of an mRNA COVID-19 vaccine (or 2 doses plus a confirmed COVID infection) and are looking for a needle-free booster option.
DijonAges 18–60 - NCT07529197Recruiting
Study of Immunoadsorption Treatment for Post-Infectious ME/CFS
This study observes how a blood-cleaning treatment called immunoadsorption works in patients with ME/CFS (severe fatigue condition) who have specific immune markers. Researchers will track whether this treatment helps reduce symptoms and improve daily functioning.
Berlin, State of BerlinAges 18–65 - NCT05787418Enrolling by invitationPhase 3
Nasal spray to prevent COVID-19 after a close exposure
This Phase 3 trial tests whether a medicated nasal spray can stop COVID-19 from starting after you’ve been exposed to someone who recently tested positive. You must start very soon after the person became symptomatic, and you’ll be checked for eligibility based on timing and your health history.
BeijingAges 12–85 - NCT05610423Enrolling by invitation
Study of heart inflammation after COVID-19 vaccination in Norway
This study looks at people who may have developed myocarditis or pericarditis (inflammation of the heart muscle or the lining around the heart) shortly after a COVID-19 vaccine. It compares their health records to vaccination records to understand who is affected and when, which may help improve future care.
OsloAges 5 years+
Hear when a new COVID-19 Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for covid-19 infection?
- Yes. Clin2 currently lists 195 recruiting covid-19 infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a covid-19 infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a covid-19 infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.