Clinical trials
COVID-19 clinical trials
Below are recruiting covid-19 clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04442191RecruitingPhase 2
Convalescent plasma for hospitalized COVID-19 patients over 40
This trial tests whether donated “recovered patient” plasma (antibodies from people who had COVID-19) can improve outcomes for people hospitalized with COVID-19. It focuses on patients early in their illness who need a small amount of oxygen.
Chicago, IllinoisAges 40 years+ - NCT04363541Recruiting
Thermotherapy for mild to moderate COVID-19 symptoms
This trial studies whether local heat treatment (thermotherapy) can improve outcomes for people with mild to moderate COVID-19. It’s designed for people early in their illness (within 5 days) who still have good oxygen levels.
Guadalajara, JaliscoAges 18 years+ - NCT05387369Recruiting
Real-world study of Paxlovid for hospitalized COVID-19 patients
This study checks how Paxlovid works in everyday care for people who are hospitalized with confirmed COVID-19. If you have a positive COVID-19 test and mild to moderate symptoms, this trial may help doctors understand how well the treatment performs outside of tightly controlled settings.
ShanghaiAges 12 years+ - NCT05191381Recruiting
Immune treatment using exosome therapy for severe COVID-19
This trial tests whether immune-supporting treatment made from exosomes can help people with critically severe COVID-19 and lung damage. If you qualify, you may receive this therapy as part of the study to see if it improves outcomes.
UlmAges 18–90 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT07746544RecruitingPhase 3
Secutrelvir for treating covid-19 in adolescents and adults
This study tests an experimental oral antiviral, secutrelvir, for people with mild to moderate COVID-19 who are not sick enough to need hospital care. The medicine aims to reduce symptoms and help you recover faster.
Multiple LocationsAges 12–74 - NCT05218356RecruitingPhase 2
Codivir trial for hospitalized moderate COVID-19
This trial tests whether Codivir can help people hospitalized with moderate COVID-19 recover better than a placebo (inactive pill). It will compare outcomes while participants receive standard hospital care.
Paulo Prata, Barretos/SP/BRAAges 18–75 - NCT05268523Recruiting
Online self-management program for long COVID symptoms
This trial tests an online self-management program to help people cope with long COVID symptoms in everyday life. It may help if you’re struggling with ongoing symptoms like mood changes, memory/thinking issues, or physical problems after COVID.
Toronto, OntarioAges 18 years+ - NCT05126589Recruiting
COVID-19 respiratory sample testing using virus genetic clues
This study looks at respiratory samples from adults after COVID-19 to better understand what viruses may be present and how they change over time. If you live in Hong Kong and can consent, you may be able to help researchers learn from your samples and symptoms.
Hong Kong, Hong KongAges 18 years+ - NCT07445971RecruitingPhase 1
Study of MDX2301 for healthy adults and those at higher risk for severe COVID-19
This trial tests an investigational drug called MDX2301 to see if it's safe in healthy adults and in adults who are at higher risk for severe COVID-19. Higher risk means you have conditions like asthma, diabetes, heart disease, or other listed health issues.
Las Vegas, NevadaAges 18–64 - NCT05553743Recruiting
Study of donated breast milk and how it affects child health
This study looks at breast milk donated for research and how it may relate to infant and child health. If you’re an adult who is breastfeeding and can donate extra milk, you may be able to participate.
San Diego, CaliforniaAges 18 years+ - NCT06776263Recruiting
Breathing problems after COVID-19 study
This study looks at people who have ongoing breathing issues after a COVID-19 infection. It tests a simple questionnaire to see if you have dysfunctional breathing (abnormal breathing patterns) and may help guide treatment.
Stockholm, SolnaAges 18 years+ - NCT06881160Recruiting
Micro-RNA and COVID-19 study
This trial studies tiny molecules in your body called micro-RNAs (miRNAs) that may help understand how COVID-19 affects people. Participants donate blood and swab samples to see if these molecules can predict how sick someone might get.
Roma, RMAges 18 years+ - NCT06927622Recruiting
COVID-19 study for pregnant women and infants
This study follows pregnant women and their babies to learn more about COVID-19 and how it affects them. By taking part, you help researchers understand the virus and improve care for mothers and children.
Jinan, ShandongAges 18 years+ - NCT07154199Recruiting
Ultrasound for brain fog after COVID-19
This trial tests if gentle ultrasound waves to the head can help clear brain fog that lasts after a COVID-19 infection. If you've had COVID and still feel mentally slow or forgetful, this treatment might help your thinking get sharper.
Beijing, Beijing MunicipalityAges 18–75 - NCT07140094Recruiting
Long COVID Relief Through Learning Mindfulness
This study tests whether a mindfulness program can help ease long COVID symptoms. You will learn simple mindfulness techniques and see if they improve your daily life.
New York, New YorkAges 18 years+ - NCT07110714Recruiting
Kneipp water therapy for post-COVID recovery
This study tests if Kneipp hydrotherapy (a gentle water therapy) can help improve symptoms in people with Post-COVID Syndrome. You will use a smartphone app to track your heart rate and answer questionnaires.
Füssen, BavariaAges 18 years+ - NCT05650905Recruiting
Eye and blood-vessel function study after COVID-19
This study measures how well the nerves in your retina and the tiny blood vessels in your eye “couple” (work together) after COVID-19. It may help researchers understand eye-related effects of COVID-19 and long COVID, and how these processes change over time.
Vienna, State of ViennaAges 18 years+ - NCT06968442Recruiting
Obesity and severe COVID-19 study
This study looks at how obesity affects the body's response to severe COVID-19. It compares people with obesity to healthy-weight healthcare workers to understand differences in the immune system.
Rotterdam, South HollandAges 18–65 - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT06960928RecruitingPhase 3
Low dose sirolimus for long COVID
This trial tests if a low dose of sirolimus, a medicine that calms the immune system, can help people with long COVID. If you have had long COVID symptoms for at least 6 months, like severe fatigue, brain fog, or chest pain, you may be able to join.
New York, New YorkAges 18 years+ - NCT06928506Recruiting
Study of Hi-OxSR for Long COVID treatment
This study tests whether a treatment called Hi-OxSR can help with lingering symptoms of Long COVID, especially problems with thinking and memory. You may be eligible if you've had COVID-19 at least 3 months ago and still have ongoing symptoms that affect your thinking.
Edmonton, AlbertaAges 18 years+ - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100
Hear when a new COVID-19 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
COVID-19 trials by city
Studies with a site in or near these metro areas.
COVID-19 trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for covid-19?
- Yes. Clin2 currently lists 270 recruiting covid-19 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a covid-19 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a covid-19 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.