Clinical trials
COVID-19 Respiratory Infection clinical trials
Below are recruiting covid-19 respiratory infection clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05126589Recruiting
COVID-19 respiratory sample testing using virus genetic clues
This study looks at respiratory samples from adults after COVID-19 to better understand what viruses may be present and how they change over time. If you live in Hong Kong and can consent, you may be able to help researchers learn from your samples and symptoms.
Hong Kong, Hong KongAges 18 years+ - NCT05689034RecruitingPhase 2/Phase 3
Azvudine for early COVID-19 in higher-risk adults
This trial studies azvudine in adults with early COVID-19 symptoms to see if it can prevent the illness from getting severe. You may qualify if you’re within about 5 days of symptom start and have risk factors for worsening disease.
Beijing, Beijing MunicipalityAges 18–120 - NCT04276896RecruitingPhase 1/Phase 2
COVID-19 Synthetic Minigene Vaccine Trial
This trial tests a new type of COVID-19 vaccine called a synthetic minigene vaccine. It is for people with a recent COVID-19 infection (within the past 7 days) to see if the vaccine is safe and helps the immune system fight the virus.
Shenzhen, GuangdongAges 6 months–80 years - NCT07739446Enrolling by invitation
Do face masks help prevent catching the flu or COVID-19?
This trial looks at whether wearing surgical masks when out in public can reduce your chances of getting the flu or COVID-19. If you join, you'll be assigned by chance to either wear a mask outside for 3-4 months or not wear one, and you'll be tested if you get sick.
ChibaAges 20–49 - NCT03808922RecruitingPhase 3
DAS181 treatment for COVID-19 lung infection in immune-compromised adults
This Phase 3 trial tests DAS181 to treat lower lung (chest) viral infections in people with weakened immune systems, including a COVID-19 subgroup. It may help by targeting certain viruses in the lungs, but joining depends on your oxygen needs, recent diagnosis, and other safety factors.
Duarte, CaliforniaAges Any age - NCT04442191RecruitingPhase 2
Convalescent plasma for hospitalized COVID-19 patients over 40
This trial tests whether donated “recovered patient” plasma (antibodies from people who had COVID-19) can improve outcomes for people hospitalized with COVID-19. It focuses on patients early in their illness who need a small amount of oxygen.
Chicago, IllinoisAges 40 years+ - NCT04448145Recruiting
Study why COVID lasts after recovery
This study looks at what factors may make COVID-19 symptoms or infection effects last after someone has recovered. It also collects certain body samples to better understand why this persistence happens.
New York, New YorkAges 7 years+ - NCT04582903Recruiting
Send-in sample collection study for immune response to respiratory viruses
This study collects sent-in samples to better understand how your immune system responds during a COVID-19–like illness and after you recover. It may help researchers learn why some people get sick and others stay uninfected, and how immune protection works over time.
Rockville, MarylandAges 1 day–99 years - NCT04887623Recruiting
Blood and breathing marker tracking in hospitalized COVID-19
This study follows hospitalized people with recent COVID-19 to see how infection and inflammation markers change over time. It may help doctors better understand what’s happening in the body as breathing problems develop and treatments are given.
Hradec KrálovéAges 18–90 - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT05218356RecruitingPhase 2
Codivir trial for hospitalized moderate COVID-19
This trial tests whether Codivir can help people hospitalized with moderate COVID-19 recover better than a placebo (inactive pill). It will compare outcomes while participants receive standard hospital care.
Paulo Prata, Barretos/SP/BRAAges 18–75 - NCT05246098Recruiting
Rehabilitation program study for young and adult ICU COVID/respiratory survivors
This study looks at whether a rehabilitation approach improves recovery outcomes for people who survived COVID-19 or a serious breathing infection and needed ICU/PICU care. It may help those still dealing with physical or functional problems after their critical illness.
Calgary, AlbertaAges Any age - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05774093Recruiting
Study how COVID immunity affects reinfection risk
This study looks at how well COVID-19 protection (immune barrier) holds up over time and how likely people are to get reinfected. It may help researchers understand who is more at risk after prior infection and why.
Guangzhou, GuangdongAges Any age - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99 - NCT05892549Recruiting
Phone-based monitoring to detect worsening COVID-19 early
This study tests whether a phone app that listens to your voice and breathing can spot signs your COVID-19 is getting worse sooner. If you qualify, you’ll use the COVOICE app on your mobile phone for monitoring.
Saint-MandéAges 18 years+ - NCT06168019Recruiting
Flu and COVID-19 study for pregnant women in Nagpur
This study follows pregnant women in Nagpur to understand how influenza and COVID-19 affect them and their babies. Participants will be contacted twice a week for symptom checks and may provide blood samples at key points during pregnancy.
Boston, MassachusettsAges 18–50 - NCT06402318Recruiting
Quick breath test for COVID, flu, and RSV
This study tests a breathalyzer device that quickly detects COVID-19, flu, and RSV from your breath. If you are already being tested for these viruses, you may join to see if this new method works as well as the usual swab test.
Fort Sam Houston, TexasAges 18–89 - NCT06490744Recruiting
Lung function after COVID-19 in lung transplant patients
This study looks at how lung function changed over time in lung transplant patients who had a moderate to severe COVID-19 infection. It may help doctors understand how to better care for transplant patients after a serious COVID-19 illness.
StrasbourgAges 18 years+ - NCT06571136Recruiting
Can a breath test detect COVID-19?
This study tests a new device that measures chemicals in your breath to see if it can quickly tell if you have COVID-19. If successful, it could lead to a fast, non-invasive way to check for the virus.
Everett, WashingtonAges 18–70 - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Tucson, ArizonaAges 18 years+ - NCT06736288RecruitingPhase 4
Buccalin® tablets to prevent repeat lung infections
This trial tests whether Buccalin® tablets can help adults who get frequent lower respiratory infections (like bronchitis or COPD flare-ups). It's a phase 4 study collecting more data on safety and how well the medicine works to prevent these infections from coming back.
AlessandriaAges 18–99 - NCT06744660Recruiting
Testing a new COVID-19 test for people with symptoms
This study is testing a new, easy-to-use COVID-19 test called the Metrix COVID-19 Test. If you have a fever or other cold or flu-like symptoms today, you may help confirm if this test works well.
Birmingham, AlabamaAges 2 years+
Hear when a new COVID-19 Respiratory Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for covid-19 respiratory infection?
- Yes. Clin2 currently lists 72 recruiting covid-19 respiratory infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a covid-19 respiratory infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a covid-19 respiratory infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.