Clinical trials
Critically Ill Patients clinical trials
Below are recruiting critically ill patients clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04475666Recruiting
Protein replacement through tube feeding in ICU patients
This study tests whether giving a different protein through tube feeding can help critically ill adults in the ICU. You may be eligible if you are already receiving nutrition through a stomach or gut tube and are on a breathing machine.
Jeddah, JeddahAges 18 years+ - NCT04580680Recruiting
Testing a blood-filter treatment in critically ill ICU patients
This study looks at an add-on blood-filter treatment used in the ICU to help remove harmful substances like waste products, inflammation signals, or toxins from the blood. Results may help doctors understand whether this approach improves care and how it should be used.
FlorenceAges Any age - NCT05112328Recruiting
Pancreatic enzyme added to feeding for ICU adults
This study tests whether adding pancreatic digestive enzymes to tube feeding can improve digestion and outcomes in critically ill adults who have higher risk of not producing enough digestive enzymes. If you qualify, you may receive the enzyme supplement or a comparison treatment while you’re in the ICU.
Seoul, Jongno-guAges 18 years+ - NCT05359601Recruiting
Testing how often to change infusion tubing in ICU
This trial compares timing for replacing the IV infusion tubing in critically ill ICU patients. It may help reduce infection risk while avoiding unnecessary changes by finding an interval that is safe and practical.
Wuhan, HubeiAges 18 years+ - NCT05450185Recruiting
Test filter lifespan during continuous kidney dialysis
This study looks at whether the lifespan (how long they can be used) of dialysis filters can be optimized during continuous kidney dialysis for very sick adults. If successful, it may improve care and use of dialysis supplies for people with dialysis-dependent kidney injury.
InnsbruckAges 18 years+ - NCT05587517RecruitingPhase 2
Support for family decision-makers of critically ill patients
This Phase 2 study tests interventions to support family surrogate decision-makers when a loved one is very sick in the ICU and is nearing end-of-life. It may help by reducing distress and pre-loss grief through structured support delivered by phone or video.
Miami, FloridaAges 18 years+ - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05883137Recruiting
High-flow nasal oxygen during intubation in the ICU
This trial looks at using a special, fast-flow oxygen device through the nose during intubation in critically ill adults. It may help keep oxygen levels safer while a breathing tube is placed.
Stockholm, Stockholm CountyAges 18–100 - NCT05937789Recruiting
Vitamin D3 during early ICU care to help critically ill adults
This trial tests whether starting vitamin D3 soon after ICU admission helps critically ill adults with low vitamin D levels. It may help correct low vitamin D and possibly improve recovery, depending on your health situation.
TaipeiAges 18 years+ - NCT05993390Recruiting
Reversing muscle relaxants in ICU patients
This trial tests two medicines that help reverse the muscle-relaxing drugs given to patients on breathing tubes in the intensive care unit. The goal is to see which one works better and faster so patients can wake up sooner.
Seoul, Jongno-guAges 19–90 - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT06220825Recruiting
Breathing support practices in critically ill children
This trial looks at how doctors manage breathing support for children in the intensive care unit. It may help improve care for kids who need help breathing.
GroningenAges Up to 18 years - NCT06234787Recruiting
Continuous glucose monitoring in ICU patients
This study looks at how well continuous glucose monitors (small sensors under the skin that track sugar levels) work in ICU patients who need insulin. If you are in the ICU, on insulin, and already have a sensor, you may be able to join.
MadridAges 18 years+ - NCT06510348Recruiting
Feeding support for ventilated patients with gut issues
This trial tests a special approach to nutrition for patients on breathing machines who have trouble digesting food. It aims to see if the new method helps meet nutritional needs better.
BucharestAges 18 years+ - NCT06543602Recruiting
Monitoring agitation in ICU patients with a video camera
This trial uses a special camera to monitor ICU patients who may become agitated. By watching your face and body movements, doctors hope to detect agitation early and improve your care.
Hangzhou, ZhejiangAges 18–65 - NCT07530146RecruitingPhase 3
Sedation Medications for Older ICU Patients on Breathing Machines
This study compares two sedation medications—propofol alone versus propofol combined with ketamine—in older patients in the ICU who are on breathing machines due to infection or lung problems. The goal is to find which combination is safer and works better for keeping patients calm and comfortable.
CairoAges 65 years+ - NCT06667999RecruitingPhase 4
Intensive care platform trial for adult ICU patients
This major trial tests multiple treatments at once for adults admitted to the ICU. If you are an ICU patient, you may be able to join and receive one of several possible treatments aimed at improving recovery.
AabenraaAges 18 years+ - NCT06727903Recruiting
Predicting survival for older ICU patients
This study aims to create a tool to predict survival in older adults (75+) who are admitted to the ICU from the emergency room. It may help doctors better understand individual risks and make more informed care decisions.
Badalona, BarcelonaAges 75 years+ - NCT06825377Recruiting
Comparing high-protein vs. standard nutrition for ICU patients
This trial tests whether a high-protein diet or standard protein diet is better for critically ill patients who are at risk for refeeding syndrome (dangerous shifts in fluids and minerals when starting nutrition after starvation). The goal is to see which type of nutrition helps recovery.
TehranAges 18–65 - NCT06923462Recruiting
VoiceLove app for ICU patients on a ventilator
This study tests a special app called VoiceLove that helps patients in the ICU who are on a breathing machine communicate with their family and care team. The goal is to reduce confusion and improve connection and satisfaction for everyone involved.
Nashville, TennesseeAges 18 years+ - NCT06950294RecruitingEarly Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator
This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.
Boston, MassachusettsAges 18 years+ - NCT07001696Recruiting
Predicting breathing support needs with chest X-ray and blood gas
This trial looks at whether combining a chest X-ray and a blood gas test can help doctors decide if a critically ill patient needs a breathing machine (mechanical ventilation). It aims to find a better way to make this important decision.
Zagazig, Al SharqiaAges 18 years+ - NCT07032870Recruiting
Ultrasound reliability study in ICU patients
This study checks how reliably different physical therapists can measure muscles and nerves using ultrasound in patients who are awake and stable in the intensive care unit (ICU). It aims to improve muscle assessment techniques for critically ill adults.
Santiago, Metropolitan RegionAges 18 years+
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Common questions
- Are there clinical trials for critically ill patients?
- Yes. Clin2 currently lists 317 recruiting critically ill patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.