Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 333 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07775352Recruiting
Ultrasound-guided care for inflammatory bowel disease
This study tests whether using ultrasound to guide treatment can help manage inflammatory bowel disease. You may join if you are having an endoscopy to assess your disease.
BangkokAges 18 years+ - NCT07697456RecruitingPhase 2
Study of advanced therapies for Crohn's or ulcerative colitis
This study tests advanced treatments for people with moderate to severe Crohn's disease or ulcerative colitis who haven't responded to at least one previous therapy. It aims to find better options for managing these conditions.
Dothan, AlabamaAges 18–75 - NCT07337902Recruiting
Comparing pain medicines for menstrual cramps in Crohn’s disease
This study tests two common over-the-counter pain relievers (ibuprofen and acetaminophen) to see which works better for menstrual cramps in women who also have Crohn's disease while in remission. If you have Crohn's and painful periods, this may help you find a safer option.
Chapel Hill, North CarolinaAges 18–44 - NCT07034664Recruiting
Ultrasound to predict Guselkumab response in Crohn's disease
This trial tests if a medication called Guselkumab can help people with moderate to severe Crohn's disease. It uses a special ultrasound to see how the bowel responds to treatment.
Changsha, HunanAges 18–80 - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Birmingham, AlabamaAges 18 years+ - NCT06430801RecruitingPhase 3
Study of tulisokibart for moderate to severe Crohn's disease
This trial tests a new medicine called tulisokibart for people with moderate to severe Crohn's disease. The medicine may help reduce inflammation and improve symptoms. It is for those who have not had success with other treatments.
Dothan, AlabamaAges 16–80 - NCT06405087RecruitingPhase 3
Long-term study of vedolizumab for children with IBD
This study is for children and teenagers with ulcerative colitis or Crohn's disease who have already completed a previous vedolizumab study and are doing well. It will look at the long-term safety and effectiveness of continuing vedolizumab treatment.
Phoenix, ArizonaAges 2–17 - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Mobile, AlabamaAges 2 years+ - NCT04646187Enrolling by invitationPhase 4
Lowering biologic doses for Crohn’s and ulcerative colitis
This trial tests whether people with Crohn’s disease or ulcerative colitis who are currently well-controlled can safely use less-frequent anti-TNF medicine. It may help reduce treatment intensity while keeping inflammation under control.
GhentAges 12–25 - NCT07649408Recruiting
How New Crohn's Treatments Affect Sleep Quality
This study looks at whether new biologic or targeted medications for Crohn's disease improve sleep quality. You would wear a watch while sleeping and answer questions about your sleep to help researchers understand if these advanced treatments help you sleep better.
Tel AvivAges 18 years+ - NCT07338565Recruiting
Magnesium study for gut conditions
This trial looks at magnesium levels in people with inflammatory bowel disease, an ileostomy, or bile acid diarrhea, compared to healthy volunteers. It aims to understand how these conditions affect magnesium in the body.
Aarhus NAges 18 years+ - NCT07298421RecruitingPhase 3
Testing afimkibart for children with Crohn's disease
This trial tests a medicine called afimkibart for children with moderately to severely active Crohn's disease. It aims to see how well the drug works and how safe it is when used for both starting and ongoing treatment.
New York, New YorkAges 2–17 - NCT07093294Recruiting
Predicting vedolizumab success with ultrasound in early Crohn's
This study uses intestinal ultrasound to see if vedolizumab can heal the gut in people recently diagnosed with Crohn's disease. It aims to find early signs that the treatment is working.
Changsha, HunanAges 18–80 - NCT06819891RecruitingPhase 3
Study of afimkibart for active Crohn's disease
This trial tests a new medicine called afimkibart for people with moderately to severely active Crohn's disease that has not responded well to other treatments. It aims to see if the medicine can safely reduce inflammation and improve symptoms.
Dothan, AlabamaAges 16–80 - NCT06819878RecruitingPhase 3
Afimkibart for moderate to severe Crohn's disease
This study tests an experimental drug called afimkibart for people with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can help control symptoms and reduce inflammation over time.
Dothan, AlabamaAges 16–80 - NCT06456593RecruitingPhase 2
Obefazimod for moderate to severe Crohn's disease
This trial tests an experimental oral medication called obefazimod for people with moderate to severe Crohn's disease. It aims to see if the drug can reduce inflammation and improve symptoms when other treatments have not worked well.
Fairhope, AlabamaAges 18–75 - NCT06424769Enrolling by invitation
Managing Inflammatory Bowel Disease with Text Message Surveys
This study aims to improve care and reduce health gaps for people with inflammatory bowel disease using text-message surveys to track symptoms and guide better disease management.
Scottsdale, ArizonaAges 13 years+ - NCT06001450Recruiting
Plastics and toxins in pregnant women and families
This study looks at how plastics and toxins in the environment might affect inflammation in the gut, especially in pregnant women with Crohn's disease and their families. It will help doctors understand if these chemicals play a role in bowel inflammation during pregnancy.
New York, New YorkAges 18 years+ - NCT07141238Recruiting
Microplastics in kids with inflammatory bowel disease
This study looks at whether tiny plastic particles (called microplastics) are found in the guts of children with and without inflammatory bowel disease. By analyzing samples taken during a routine endoscopy, researchers hope to learn if these particles might play a role in the disease.
GdanskAges Up to 18 years - NCT07619547Recruiting
Bowel disease immune system study
This study is looking at how the immune system works in people with inflammatory bowel disease (IBD), which includes conditions like Crohn's disease and ulcerative colitis. By comparing blood or tissue samples from people with and without IBD, researchers hope to find better ways to treat the disease in the future.
Bethesda, MarylandAges 18–85 - NCT06780683Recruiting
Testing upadacitinib for inflammatory bowel disease
This study tests a medication called upadacitinib for people with inflammatory bowel disease (ulcerative colitis or Crohn's). The goal is to see how well it works and if it's safe.
Guangzhou, GuangdongAges Any age - NCT07383844Recruiting
Physical activity for teens with IBD
This study looks at what helps or stops teenagers with inflammatory bowel disease (Crohn's disease or ulcerative colitis) from being physically active. It involves completing questionnaires and an interview to understand your experience.
NiceAges 10–17 - NCT06548399Recruiting
Bacteria study for IBD patients with ongoing abdominal pain
This study looks at bacteria in your gut that may produce chemicals linked to ongoing pain in Crohn's disease or ulcerative colitis, even when the disease itself is not very active. Researchers want to understand why some people still have moderate to severe abdominal pain even after their inflammation has calmed down.
Hamilton, OntarioAges 18–70 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 333 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.