Clinical trials · Denver, CO
Cystic Fibrosis clinical trials in Denver
We’re tracking 25 recruiting cystic fibrosis studies with a site in or near Denver — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Denver
- NCT06683092Recruiting
Restarting triple therapy with close monitoring for side effects
This trial tests whether carefully restarting a triple-combination CFTR modulator (VTD) is safe and helpful for people with cystic fibrosis who had to stop or change Trikafta because of mental health side effects or liver injury. You will be closely monitored with surveys and daily diaries to ensure your safety.
Denver, ColoradoAges 6 years+ - NCT06950892Recruiting
Remote sputum collection study for cystic fibrosis
This study tests if people with cystic fibrosis can collect sputum samples at home and mail them in, instead of coming to the clinic. It aims to make participation easier for patients.
Denver, ColoradoAges 18 years+ - NCT06559150RecruitingPhase 2
Study of ensifentrine for non-cystic fibrosis bronchiectasis
This trial tests an inhaled drug called ensifentrine in people with bronchiectasis (damaged, widened airways in the lungs). The goal is to see if it can reduce flare-ups and improve symptoms.
Denver, ColoradoAges 18–80 - NCT06429176RecruitingPhase 2
SPL84 for cystic fibrosis with 3849+10kb mutation
This trial tests a new drug called SPL84 for people with cystic fibrosis who have a specific gene mutation (3849+10kb C->T). It aims to see if the drug is safe and can improve lung function. The study has two paths: one for people not taking certain CF drugs, and one for those who are already on Trikafta or Alyftrek.
Denver, ColoradoAges 18 years+ - NCT05248230RecruitingPhase 2
Study drug for adults with cystic fibrosis lung disease
This Phase 2 trial tests 4D-710 to improve lung health in adults with cystic fibrosis who either cannot take CFTR modulator medicines or are not doing well enough on them. You may be eligible if you have moderate lung function and stable oxygen levels, and you meet other safety and health requirements.
Denver, ColoradoAges 18 years+ - NCT07071324Recruiting
CF Wellness Program for Fatigue
This wellness program tests if coaching sessions can help people with cystic fibrosis who feel tired. It is a remote program you can join using your phone or computer, as long as you get CF care at a participating center.
Denver, ColoradoAges 18 years+ - NCT06504589Recruiting
Study for CF treatments for people without modulators
This study tests new treatments for cystic fibrosis in people who cannot take or choose not to take current CFTR modulators. It aims to find better options for managing CF.
Denver, ColoradoAges 12 years+ - NCT04579211Enrolling by invitation
Urine testing to skip repeated NTM sputum checks in cystic fibrosis
This study looks at whether a urine test (instead of repeated sputum—mucus—from the lungs testing) can help determine who with cystic fibrosis does not have certain lung germs called NTM. If the urine test works, it could reduce the need for lung sample testing while still keeping people safe.
Denver, ColoradoAges 18 years+ - NCT04469439Recruiting
Sinus surgery in adults with cystic fibrosis
This study looks at how endoscopic sinus surgery affects people with cystic fibrosis who have ongoing sinus problems even after medical treatments. It may help doctors understand whether surgery plus ongoing care improves symptoms and quality of life.
Denver, ColoradoAges 18–99 - NCT05686837Enrolling by invitation
Study of how lung bacteria spreads in people with cystic fibrosis
This trial follows people with cystic fibrosis to better understand how “nontuberculous mycobacteria” (a type of lung germ) spreads between healthcare visits and care settings. It may help improve future prevention and monitoring strategies for CF patients who have had these bacteria.
Denver, ColoradoAges 1 month–99 years - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Denver, ColoradoAges 6 years+ - NCT06296394Recruiting
Health outcomes for new parents with cystic fibrosis
This study looks at the health of parents with cystic fibrosis who have recently become a first-time parent to a young child. It aims to understand how parenting affects their health.
Denver, ColoradoAges 18 years+ - NCT06998043RecruitingPhase 2
Phage therapy for cystic fibrosis with pseudomonas lung infection
This trial tests a new treatment using phages (viruses that kill bacteria) for people with cystic fibrosis who have a chronic pseudomonas lung infection. It aims to see if adding phages to your usual care can help control the infection.
Denver, ColoradoAges 18 years+ - NCT04294043RecruitingPhase 1
Gallium IV study for adults with cystic fibrosis and NTM lung infection
This Phase 1 study tests whether an IV medicine called gallium can treat hard-to-treat lung infections (NTM) in adults with cystic fibrosis. It is mainly for people who have not been treated yet for NTM or who have NTM that has not cleared despite antibiotics.
Denver, ColoradoAges 18 years+ - NCT07450547RecruitingPhase 2
A trial of a new medicine for cystic fibrosis and pancreatic problems
This trial tests a new medicine (ANG003) for people with cystic fibrosis who have severe pancreatic problems. It looks at how safe and effective the medicine is, and whether it helps with digestion.
Denver, ColoradoAges 12 years+ - NCT06546943Recruiting
Glucose monitoring in youth with cystic fibrosis
This study uses a continuous glucose monitor (a small sensor on the arm) to track blood sugar levels in young people with cystic fibrosis during a lung infection flare-up (called a pulmonary exacerbation). It aims to see if glucose changes can help guide treatment.
Aurora, ColoradoAges 6–25 - NCT04509050Recruiting
Testing a highly effective CF medicine in young children
This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.
Aurora, ColoradoAges Up to 10 years - NCT06587126Recruiting
Can a Cough Monitor Work in Children?
This study tests a way to monitor coughing in children at home, including children with cystic fibrosis and healthy children. It will help researchers learn how well a cough monitor works in real life.
Aurora, ColoradoAges 1–18 - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Aurora, ColoradoAges 12 years+ - NCT07048574Recruiting
Mood and behavior in children with cystic fibrosis
This study looks at mood and behavior in children with cystic fibrosis (CF) under 12. By following children over time, researchers hope to better understand and help with depression, anxiety, and behavior challenges that may come up.
Aurora, ColoradoAges 1.5 years–11 years - NCT05844449Enrolling by invitationPhase 3
Check long-term safety and effectiveness of CF medicines
This Phase 3 study looks at how well and how safely Vanzacaftor/Tezacaftor/Deutivacaftor works over the long term in people with cystic fibrosis who already took the study medicine before. It may help confirm the best long-term plan and spot important safety issues.
Aurora, ColoradoAges 1 year+ - NCT04731272RecruitingPhase 2
Weekly GLP-1 medicine for blood sugar issues in adults with CF
This Phase 2 trial tests a weekly GLP-1 medicine (dulaglutide) to improve blood sugar control in adults with cystic fibrosis (CF) who have trouble managing glucose. It may help people with CF-related prediabetes or diabetes by improving how their body handles sugar.
Aurora, ColoradoAges 18 years+ - NCT06449677RecruitingTeam says not enrollingPhase 3
Bionic pancreas study for cystic fibrosis related diabetes
This trial tests if an automated insulin delivery system (the iLet bionic pancreas) can safely and effectively manage blood sugar in people with cystic fibrosis related diabetes (CFRD). If you have CFRD and already use insulin, this study may help you learn if a bionic pancreas works well for you.
Aurora, ColoradoAges 14 years+ - NCT06191640Recruiting
Study of sinus disease in young children with cystic fibrosis
This study looks at sinus problems in young children with cystic fibrosis. One group of children starts a new medicine called a highly effective modulator (like Trikafta), and the other group does not take this medicine. The goal is to see how the medicine affects sinus health over time.
Aurora, ColoradoAges 2–8
Hear when a new Cystic Fibrosis trial opens near Denver, CO
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Cystic Fibrosis trials in other cities
Where these studies are running near Denver
Institutions with a site for the recruiting cystic fibrosis studies listed above.
- National Jewish Health · 15 studies
- Children's Hospital Colorado · 10 studies
- University of Colorado Anschutz Medical Campus · 2 studies
- UCHealth University of Colorado Hospital
What taking part in a cystic fibrosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cystic fibrosis studies in Colorado.
Common questions
- Are there cystic fibrosis clinical trials near Denver?
- Yes. We're currently tracking 25 recruiting cystic fibrosis studies with a site near Denver, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cystic fibrosis study near Denver?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Denver to take part?
- Not necessarily. These studies have a site near Denver, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cystic fibrosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cystic fibrosis studies open near Denver regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.