Clinical trials
Dementia, Mild clinical trials
Below are recruiting dementia, mild clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07499570Recruiting
Talk therapy using AI for older adults with memory issues
This study tests an AI-powered talk therapy for older adults with mild memory problems who live at home. It aims to reduce challenging behaviors like agitation, anxiety, or depression by delivering personalized support through a computer or tablet.
Indianapolis, IndianaAges 65 years+ - NCT06597942RecruitingPhase 1/Phase 2
Deep TMS for Alzheimer's disease
This trial tests a non-invasive brain stimulation technique called deep repetitive TMS on a brain region linked to memory. It aims to see if this treatment can improve symptoms in people with mild-to-moderate Alzheimer's disease.
Los Angeles, CaliforniaAges 60–100 - NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT06489548RecruitingPhase 2
Foralumab for Early Alzheimer's Disease
This study tests an experimental drug called Foralumab, which aims to calm overactive immune cells in the brain linked to Alzheimer's. It may help slow memory loss in people with early-stage Alzheimer's.
Boston, MassachusettsAges 60–85 - NCT06572748Recruiting
Cooking study for older adults with memory concerns
This study tests a cooking program called Chef Anchor 3.0 for older adults with mild memory problems or dementia. It looks at whether learning to cook can help with thinking skills and daily life.
Hong KongAges 60 years+ - NCT06650969Recruiting
Early detection of cognitive decline in type 2 diabetes
This study is looking at ways to catch early thinking and memory changes in people with type 2 diabetes. By joining, you may help doctors learn how to spot problems sooner and find better ways to help.
Nanjing, JiangsuAges 45 years+ - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT07012993RecruitingPhase 2
Very low dose PET brain scan study
This study tests whether using a very low dose of radiation for a brain PET scan can still give clear images. If you are eligible, you will get a type of radioactive tracer that helps show amyloid plaques in the brain, often used in Alzheimer's research.
Englewood, New JerseyAges 18–120 - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07272811Recruiting
Computer memory testing for early Alzheimer's signs
This study uses a computer-based platform to test memory and thinking in healthy adults and in people with mild memory concerns (called aMCI). The goal is to better understand how memory changes with age and to spot early signs of Alzheimer's disease.
Milan, ItalyAges 55–80 - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06017505Enrolling by invitation
Using eSAGE for early detection of cognitive decline
This study uses a simple computer-based self-assessment (eSAGE) to detect early signs of memory or thinking problems. It may help identify cognitive impairment sooner and track changes over time.
Columbus, OhioAges 50 years+ - NCT05457998Enrolling by invitation
Study of Alzheimer’s brain markers using memory testing
This trial looks for signs of Alzheimer’s disease in the brain by using memory and thinking tests, and related study procedures. It may help researchers find better ways to identify Alzheimer’s-related changes earlier.
Providence, Rhode IslandAges 50–80 - NCT05697588Recruiting
Study blood and brain markers from mild memory loss to dementia
This study looks for “biomarkers” (measurable signs from blood and brain tests) that may help predict who with mild cognitive impairment (MCI) could later develop dementia. Results may help doctors spot risk earlier and better plan care.
Beijing, Beijing MunicipalityAges 50–85 - NCT07731334Recruiting
Memory problems in non-neurology rehab patients
This study looks at how common mild cognitive impairment and dementia are in people staying in rehabilitation units for heart, lung, or orthopedic problems. It aims to understand memory and thinking issues that may be overlooked in these settings.
Florence, FIAges 45 years+ - NCT04240561Recruiting
Study of hearing aid results in people with Alzheimer’s dementia
This study looks at how much hearing aid outcomes vary in older adults who have Alzheimer’s dementia or mild memory problems. It may help researchers understand what hearing aids work best and for whom.
Chicago, IllinoisAges 50–90 - NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT05606341RecruitingPhase 1
Testing a diabetes-style shot to boost brain immunity in early Alzheimer’s
This Phase 1 study tests whether stimulating the immune system (through a receptor called TLR9) is safe and may affect brain changes in people with early Alzheimer’s. It mainly enrolls older adults with memory impairment confirmed by specific amyloid imaging.
New York, New YorkAges 60–85
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Common questions
- Are there clinical trials for dementia, mild?
- Yes. Clin2 currently lists 129 recruiting dementia, mild studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia, mild trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia, mild trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.