Clinical trials · California
Dementia clinical trials in California
We’re tracking 38 recruiting dementia studies with a site in California — including Phase 1, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT03638583Recruiting
Online testing study to prevent or spot Alzheimer’s early
This study invites people age 50+ who do not have dementia to do ongoing thinking tests online. If an online risk screen suggests you may be at higher risk, you may be referred for in-person body tests (biomarker assessment).
San Diego, CaliforniaAges 50–85 - NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Orange, CaliforniaAges 25–55 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Long Beach, CaliforniaAges 75 years+ - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Los Angeles, CaliforniaAges 18 years+ - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06362824Recruiting
Physical activity study for older Hispanic adults
This study tests ways to help older Hispanic/Latino(a) adults become more physically active. You will be randomly assigned to one of two programs, and the study lasts up to 20 weeks. It includes wearing a small activity tracker and filling out questionnaires.
San Diego, CaliforniaAges 55–89 - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Irvine, CaliforniaAges 55 years+ - NCT06741865Recruiting
Helping older adults keep their minds sharp (INSPIRE-Faith)
This trial tests whether certain lifestyle and thinking exercises help preserve memory and brain function in older adults, especially in the African American community. You may join if you are 55 or older and your memory is normal or mildly impaired.
Los Angeles, CaliforniaAges 55–85 - NCT06972004Enrolling by invitation
Preventing loss of independence through exercise for veterans
This study tests a gentle exercise program for veterans living in VA community living centers. The program is designed to help residents with memory problems stay independent, move better, and feel better. Staff at the center will be trained to lead the classes.
San Francisco, CaliforniaAges 18 years+ - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
San Francisco, CaliforniaAges 50 years+ - NCT05001009Enrolling by invitation
Goals of care conversation support for certain serious illnesses
This study helps primary care clinicians and their patients have structured “goals of care” conversations (about what matters most and care preferences). It may help you get clearer, earlier planning—especially if you have a serious illness and higher risk of hospitalization or death.
Palo Alto, CaliforniaAges 18 years+ - NCT03623672Enrolling by invitation
Study for early signs of Parkinson-related brain changes
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Redwood City, CaliforniaAges 18 years+
Dementia trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting dementia studies listed above.
- Cedars-Sinai Medical Center · 3 studies
- University of California San Diego · 2 studies
- University of California, Los Angeles (UCLA) · 2 studies
- VA Palo Alto Health Care System · 2 studies
- Artemis Institute for Clinical Research
- Care Access
- Clinical Trials Research
- Crenshaw Christian Center
What taking part in a dementia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Dementia trials in other states
Common questions
- Are there dementia clinical trials in California?
- Yes. We're currently tracking 38 recruiting dementia studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a dementia study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New dementia studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.