Study for early signs of Parkinson-related brain changes
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have REM sleep behavior disorder (acting out dreams during sleep).
- Your REM sleep behavior disorder is idiopathic, meaning no known cause was identified.
- You do not have REM sleep behavior disorder from another condition like narcolepsy, dementia, or Parkinson’s disease.
- You do not have other neurological disorders that could explain your symptoms.
- You can provide enough medical history for the study team to confirm the cause of your REM sleep behavior disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
This study uses MRI scans to look at the brain in people with REM sleep behavior disorder (RBD), a condition that can be an early sign of Parkinson's disease. By comparing them with healthy volunteers, researchers hope to find early markers of Parkinson's that could lead to earlier diagnosis and treatment.
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
This study looks at people diagnosed with idiopathic REM sleep behavior disorder (a sleep problem where you act out dreams) and tries to predict who may later develop another condition related to Parkinson’s. If you qualify and consent, you may be followed to understand risk factors and improve early identification.
This study follows people with sleep behavior problems, movement disorders like Parkinson's, and healthy volunteers to understand how these conditions develop and relate to each other. Researchers will use brain imaging and other tests to learn more about these diseases.
Hear when a new REM Sleep Behavior Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.