Clinical trials · Pennsylvania
Dementia clinical trials in Pennsylvania
We’re tracking 18 recruiting dementia studies with a site in Pennsylvania — including Phase 2, Phase 2/Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Jenkintown, PennsylvaniaAges 50–92 - NCT07029581RecruitingPhase 2
Testing ACP-204 for psychosis in Lewy body dementia
This trial tests a new drug called ACP-204 for people with dementia from Lewy body disease or Parkinson's who also have hallucinations or delusions. The goal is to see if the drug can safely reduce these symptoms without worsening thinking problems.
Abington, PennsylvaniaAges 55–84 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05915377Recruiting
Screening for hospital confusion in older adults
This trial is testing practical ways to recognize delirium, a sudden type of hospital confusion, in older patients. It may help your care team spot confusion earlier and respond sooner.
State College, PennsylvaniaAges 70 years+ - NCT06568107Recruiting
Sensory and environment trial for dementia with repeated vocalizations
This study tests whether a calming environment and gentle sensory activities (like soothing sounds or textures) can help nursing home residents with dementia who make repeated sounds or cries. The goal is to see if these interventions can reduce those vocalizations and improve well-being.
Philadelphia, PennsylvaniaAges 50 years+ - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Pittsburgh, PennsylvaniaAges Any age - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Philadelphia, PennsylvaniaAges 55–90 - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Pittsburgh, PennsylvaniaAges 25–55 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Philadelphia, PennsylvaniaAges 75 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+ - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Philadelphia, PennsylvaniaAges 60–90 - NCT02463708Enrolling by invitation
Caregiver program study for people with memory problems
This study tests a caregiver support program (PACE/PACENET BHL Caregiver Program) and looks at outcomes over several months. It’s for caregivers of adults with clinically significant memory/cognitive problems, using some past clinical information and follow-up reports.
Philadelphia, PennsylvaniaAges 18 years+
Dementia trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting dementia studies listed above.
- University of Pennsylvania · 6 studies
- University of Pittsburgh · 6 studies
- Thomas Jefferson University Hospital · 2 studies
- Abington Neurological Associates
- Corporal Michael J. Crescenz VA Medical Center
- Drexel University
- Flourish Research - Philadelphia
- Mount Nittany Medical Center
What taking part in a dementia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Dementia trials in other states
Common questions
- Are there dementia clinical trials in Pennsylvania?
- Yes. We're currently tracking 18 recruiting dementia studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a dementia study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New dementia studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.