Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 488 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05296291Recruiting
Compare titanium, zirconia, and another frame for missing teeth
This study compares three types of dental support frames (titanium, zirconia, and another material) for people missing teeth behind the canine. It may help find which frame works best for stability and successful treatment in that specific area.
GothenburgAges 18–100 - NCT04544839Enrolling by invitation
Test two ways to attach dentures or implants
This trial compares two different attachment systems for people who have major problems with their upper and/or lower dentures, or who want implant-supported replacement teeth. It may help your smile and chewing by improving how the replacement teeth stay firmly in place.
PuneAges 18 years+ - NCT04367766Recruiting
Tested treatment for a fresh tooth socket after front tooth extraction
This trial studies how to care for a just-removed tooth’s socket in the front of the mouth, where appearance matters. It may help improve healing and stability by using socket treatments based on the amount of remaining bone.
RomaAges 18 years+ - NCT04007783Recruiting
Test of a new plan for jaw reconstruction and implants
This study checks whether the “O-bridge protocol” helps people who need jaw surgery—either for osteonecrosis of the jaw or for oral/jaw tumors—followed by dental implant placement to support fixed teeth (not removable dentures). The goal is to improve your ability to eat, speak, and get a stable tooth replacement plan after surgery.
AntwerpAges 18 years+ - NCT07160660Enrolling by invitation
Comparing two types of partial denture anchors
This study looks at how patients feel about two ways to hold a removable partial denture in place: one uses small sticky attachments called 'extracoronal adhesive attachments' and the other uses clips called 'clasps'. It aims to see which patients prefer and how well each works over time.
Basel, BaselAges 18 years+ - NCT02891967Recruiting
Compare two tooth-filling methods for back teeth
This trial tests whether a newer “bulk-fill” way of placing tooth filling works as well as the usual step-by-step method for restoring back teeth with cavities. It aims to see which approach best meets dental quality standards over one year.
Cairo, Cairo GovernorateAges 18–38 - NCT06406751Enrolling by invitation
MI Paste and mouth bacteria in older denture wearers
This study tests whether a special paste (MI Paste) used for several months can change the natural bacteria in the mouth of older adults who wear dentures. It may help keep your mouth healthier.
Iowa City, IowaAges 65–105 - NCT07698158Recruiting
Growing Well Study: healthy growth study for young children
This study looks at how children aged 6 months to 4 years grow and develop. It involves families in Leeds, Doncaster, or East London. Researchers want to understand what supports healthy growth in early childhood.
Doncaster, West YorkshireAges 6 months–4 years - NCT06388395Enrolling by invitation
Comparison of PEEK and Conventional Dental Prostheses
This study compares two types of full-arch dental prostheses (PEEK and conventional) placed on four implants in the lower jaw, to see which works better. It may be an option if you need all lower teeth replaced and have healthy jawbone.
Sharjah cityAges 18 years+ - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT05741749Recruiting
Immediate dental implant placed right after tooth removal
This study tests a way to place a dental implant immediately after removing a hopeless back tooth, and to help the gums and bone heal better. It may help people who have enough healthy gum and bone and can follow strict mouth-care rules.
LiègeAges 18–99 - NCT07632547Recruiting
Video Help for Anxious Children at the Dentist
This study tests whether watching a video before dental treatment helps children feel less scared at the dentist. Researchers will compare a new video-based teaching method to standard care for children aged 4–6 who need simple fillings or tooth repairs.
DamascusAges 4–6 - NCT06276335Recruiting
Timing of dental implant placement and early healing
This trial compares placing a dental implant right after a tooth is pulled versus waiting for the socket to heal first. It aims to see which timing leads to better healing at the molecular level.
LondonAges 25 years+ - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07384403RecruitingPhase 4
Oxygen therapy around healing collar after surgery
This trial tests whether a topical oxygen therapy applied around a customized healing collar helps improve healing after dental implant surgery. It is for adults in good health who are ready to commit to follow-up visits.
CairoAges 21 years+ - NCT07526272Recruiting
Magnesium membrane versus bone graft for tooth implants
This study compares two methods to rebuild bone around immediate tooth implants (implants placed right after tooth extraction). The goal is to see which material—a magnesium membrane or bone graft—works better to support the implant and maintain bone structure.
GizaAges Any age - NCT05315791Recruiting
Bone-window dental procedure for missing back upper tooth
This study looks at how to place bone support for an upper back tooth replacement when part of the upper jaw bone is limited. If you’re missing one upper back tooth for at least 3 months, they may use a specific “bone window” approach guided by a 3D scan.
Hangzhou, ZhejiangAges 18–80 - NCT07624331Recruiting
PEEK vs. Standard Healing Caps for Tooth Implants
This study compares two types of temporary healing caps (PEEK and standard materials) used during dental implant surgery for a single back tooth. Researchers will measure how well the gum tissue heals around each type to see which works better.
Sungai Buloh, SelangorAges 18 years+ - NCT07082244Recruiting
Gum and bone shaping for dental implants
This study tests a procedure to improve the shape of the gum and bone around a dental implant in people with thin gums. It uses a special graft material to make the area thicker and more stable for a better-looking result.
Ann Arbor, MichiganAges 18 years+ - NCT07166679Recruiting
Larger root canal tip for healing infection in back molars
This study tests whether making the tip of the root canal slightly larger during a single root canal treatment helps the infection heal better and reduces pain afterward. It is for people with a dead lower back molar that has an infection around the root tip.
RohtakAges 18–65 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT07077694Enrolling by invitation
AI study to find missed root canals in treated lower back teeth
This study uses artificial intelligence and 3D dental imaging to check if any root canals were missed during previous root canal treatment on lower back teeth. It may help find hidden problems and guide better treatment.
Cairo, Cairo GovernorateAges 18–50 - NCT06075017Recruiting
Zirconia vs. titanium implants and biofilm buildup
This trial compares how much biofilm (a sticky layer of bacteria) builds up on two types of dental implants – one made of zirconia (a white ceramic) and one made of titanium (a metal). It's for people getting a single implant to replace a missing tooth.
Madrid, MadridAges 18–99 - NCT06363721Recruiting
Testing an oil rinse for plaque and gum health
This study tests a special oil rinse called PerioPull™ to see if it improves dental health. You may be able to join if you have plaque buildup, bleeding gums, and no deep gum pockets.
Ellicott City, MarylandAges 18 years+
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 488 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.