Clinical trials
Depression - Major Depressive Disorder clinical trials
Below are recruiting depression - major depressive disorder clinical trials, each written for real people, not researchers. We’re tracking 204 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07561632Recruiting
Early Stress Screening After Emergency Cesarean Delivery
This study looks at whether certain signs of distress right after an unexpected cesarean delivery can predict who might develop PTSD (post-traumatic stress disorder) later. Researchers want to understand this connection so they can help women who are struggling after this traumatic birth experience.
Vancouver, British ColumbiaAges 19 years+ - NCT07032480Recruiting
Sleep, Neck Pain, and Depression Study
This study looks at how sleep problems, neck pain, and depression might be connected in healthy young adults. It aims to help understand these common issues better.
Istanbul, ÜsküdarAges 18–28 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT05323864Recruiting
Altitude exposure study for anxiety and low mood
This trial looks at what happens to people with anxiety and depressive symptoms after going to high altitude with low oxygen. It may help researchers understand whether altitude affects these symptoms and how it might be managed.
Innsbruck, TyrolAges 18–65 - NCT06773338Recruiting
Can playing Tetris improve mental health for migrants?
This study tests if playing the game Tetris can help reduce stress and improve mood for Arabic-speaking immigrants who have applied for asylum. You would play Tetris a few times and report how you feel.
The Hague, NLAges 18 years+ - NCT07239609RecruitingPhase 1
ACT therapy for memory loss and their caregivers
This study tests if ACT, a type of talk therapy, helps people with mild memory loss and their care partners cope with difficult emotions. Both you and a family member or friend who helps you would participate.
Lubbock, TexasAges 18 years+ - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06456307Recruiting
Stepped care for mood and anxiety during pregnancy
This study tests a step-by-step approach to help pregnant women who are feeling anxious or down. If you are at least 28 weeks pregnant and feeling stressed, worried, or sad, the study will offer you support and check on how you are doing.
NairobiAges 14 years+ - NCT04080778Recruiting
Magnetic seizure treatment for severe bipolar or hard-to-treat depression
This trial studies whether a seizure-like therapy using magnet stimulation can quickly reduce severe depressive symptoms in people with bipolar depression or treatment-resistant depression. It may help when depression is intense and hasn’t improved enough with at least two antidepressant medicines.
Houston, TexasAges 22–85 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT06834867Recruiting
Family support to reduce depression and address partner violence in Nepal
This trial tests a program for married women, their husbands, and mothers-in-law to reduce depression and stop intimate partner violence. It includes counseling and support for families who want to stay together.
Kathmandu, BagmatiAges 15–24 - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT05868135Recruiting
Online guided therapy for depression and anxiety
This trial tests an internet-based (online) guided psychological program, called e-Meistring, for people with moderate depression plus panic disorder and social anxiety. It aims to see whether the program improves symptoms and is also worth the cost.
BergenAges 18 years+ - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06278532Recruiting
Validating psychosis assessment tools in Lithuanian
This trial tests whether three psychiatric questionnaires work well for people with schizophrenia or related disorders. If you are between 18 and 65 and have one of these diagnoses, joining may help improve care for others like you.
KaunasAges 18–65 - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT06899490Recruiting
Acupuncture study for anxiety with tongue analysis
This trial uses machine learning to analyze tongue color and anxiety scores in people getting acupuncture for anxiety. It aims to see if tongue color can help predict treatment response.
NarbonneAges 18 years+ - NCT07022925Recruiting
Wearable device for tracking hot flushes in perimenopause
This study will test if a wearable device can accurately track symptoms like hot flushes and night sweats in women going through perimenopause. If you are between 35 and 55 and experiencing these symptoms, your participation could help improve future symptom monitoring.
London, OntarioAges 35–55 - NCT05726721Recruiting
Study of treatment targets for binge eating disorder
This trial studies how binge eating disorder behaves during treatment and compares patterns over time. It may help by improving future treatment approaches for people with binge eating disorder.
Aarhus, Central JutlandAges 18 years+ - NCT06270121Recruiting
Mobile health app for healthy aging at home
This study is testing a mobile health app designed to help seniors live independently at home. If you join, you will use the app and answer surveys to see if it supports healthy aging.
SeoulAges 65 years+
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Common questions
- Are there clinical trials for depression - major depressive disorder?
- Yes. Clin2 currently lists 204 recruiting depression - major depressive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression - major depressive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression - major depressive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.