Clinical trials · New York, NY
Depression clinical trials in New York
We’re tracking 111 recruiting depression studies with a site in or near New York — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near New York
- NCT07196501RecruitingPhase 3
Study of a new add-on treatment for depression maintenance
This trial tests a new medication (NBI-1065845) added to your current antidepressant to see if it helps maintain improvement in depression. It is for people whose depression hasn't fully responded to their current oral antidepressant.
Glen Oaks, New YorkAges 18 years+ - NCT07217860Enrolling by invitationPhase 3
Long-term safety study of azetukalner for bipolar depression
This study is looking at the long-term safety of azetukalner for people with bipolar I or II depression who have already completed a previous trial of this drug. It is an open-label study, meaning everyone will receive the active medication.
Cedarhurst, New YorkAges 18–75 - NCT06547489RecruitingPhase 2
Testing zelquistinel for major depression
This study tests whether zelquistinel, an investigational drug, can reduce symptoms of major depressive disorder (a type of clinical depression). It is for people who are currently experiencing a moderate to severe depressive episode and are not taking other antidepressants.
Cedarhurst, New YorkAges 18–64 - NCT07553637RecruitingPhase 2
ALTO-207 for Adults With Hard-to-Treat Depression
This study tests whether a new medication called ALTO-207 can help people with depression that hasn't improved with standard antidepressants. You may qualify if you've tried multiple antidepressants without enough relief and are willing to add this experimental treatment to your current medication.
Cedarhurst, New YorkAges 18–75 - NCT07042217Recruiting
Brain stimulation for depression
This trial tests if a gentle electrical current applied to the head can help people with major depression. It's for adults currently in a depressive episode who haven't found relief from at least two previous antidepressants.
Woodbridge, New JerseyAges 22 years+ - NCT06941298Recruiting
Cannabis and depression study for teens and young adults
This study looks at how cannabis affects the brain and mood in teens and young adults. It compares people who use cannabis, people with depression who don't use cannabis, and healthy volunteers to understand links between cannabis use and mental health.
Orangeburg, New YorkAges 14–20 - NCT07611916Enrolling by invitation
App-based support for group therapy in the hospital
This study tests if adding a smartphone app to group therapy helps people in the hospital feel better. It is for adults who can speak English and have a smartphone.
Piscataway, New JerseyAges 18 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT05447689Recruiting
Group mind-body skills for anxious graduate students
This trial offers a weekly group program teaching mind-body skills to help reduce anxiety. It’s for graduate students who screen as having moderate or higher anxiety and can attend meetings regularly.
White Plains, New YorkAges 18 years+ - NCT06967259RecruitingPhase 1
Testing ENA-001 for Opioid-Related Breathing Problems
This study tests a new medicine (ENA-001) that helps restore normal breathing when it has slowed down too much due to opioid painkillers. Healthy volunteers will receive the drug to see how safe it is and how the body handles it.
Eatontown, New JerseyAges 18–55 - NCT06786624RecruitingPhase 3
Testing a new drug for depression that hasn't fully responded to treatment
This trial tests a new medication called NBI-1065845 added to your current antidepressant for people with depression that hasn't fully responded to treatment. It aims to see if this combination can better improve your symptoms.
Mount Kisco, New YorkAges 18 years+ - NCT06788977Recruiting
Migraine treatment in pregnancy with a nerve stimulation device
This trial tests if a device that gently stimulates a nerve on your forehead can safely treat migraines during pregnancy. You'll use the device at home and track your headaches via text or email.
Darien, ConnecticutAges 18–44 - NCT07076342RecruitingPhase 4
Glutamate receptors and cognitive behavioral therapy for insomnia
This study tests how a brain receptor called mGluR5 affects sleep and depression treatment. You may qualify if you have major depression with insomnia and are not currently on antidepressants.
Stony Brook, New YorkAges 18 years+ - NCT07095205RecruitingPhase 4
Nicotine's effect on depression in brain imaging study
This trial uses a special brain scan to see how nicotine might help treat depression. It compares people with depression to healthy volunteers to understand how nicotine affects brain chemistry related to mood.
Stony Brook, New YorkAges 18–65 - NCT06656416RecruitingPhase 2
ALTO-100 for bipolar depression
This trial tests an investigational drug called ALTO-100 in people with bipolar I or II who are currently experiencing depression. It looks at whether this new medicine can help improve depression symptoms when taken alongside your usual mood stabilizer or antipsychotic medication.
Toms River, New JerseyAges 18–70
Hear when a new Depression trial opens near New York, NY
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Depression trials in other cities
Where these studies are running near New York
Institutions with a site for the recruiting depression studies listed above.
- Neurobehavioral Research Inc · 2 studies
- Neurocrine Clinical Site · 2 studies
- Stony Brook University Medical Center · 2 studies
- Weill Cornell Medicine · 2 studies
- Clinilabs Drug Development Corporation
- https://public.smart-trial.co/#/public/649d77f0e8f8d0fb993d0c61/6626f6a04f0a3c7dd0860e14/662726d84f0a3c7dd08aeaa0/signup?lang=en-us&enforceLanguage=true
- Nathan S. Kline Institute for Psychiatric Research
- Rutgers University Behavioral Healthcare
What taking part in a depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting depression studies in New York.
Common questions
- Are there depression clinical trials near New York?
- Yes. We're currently tracking 111 recruiting depression studies with a site near New York, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depression study near New York?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in New York to take part?
- Not necessarily. These studies have a site near New York, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depression studies open near New York regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.