Clinical trials
Depressive Disorder clinical trials
Below are recruiting depressive disorder clinical trials, each written for real people, not researchers. We’re tracking 689 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07170657Recruiting
Teen Recovery Support Program
This program helps teens ages 15 to 18 who have recently been in the hospital or emergency room for suicidal thoughts or depression. It provides support and guidance to help you recover and feel stronger.
Dallas, TexasAges 15–18 - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60 - NCT07227337Recruiting
Being safe, healthy, and empowered for immigrant women
This study tests a program to help immigrant women who have faced violence and feel symptoms of PTSD or depression. It aims to improve your safety, health, and wellbeing.
Baltimore, MarylandAges 18 years+ - NCT07250061Recruiting
Self-help PTSD program for women veterans
This study tests a self-guided program to help women veterans with PTSD. You would work through coping skills on your own, with support from a group of other women veterans.
Boston, MassachusettsAges 18 years+ - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT07314892Recruiting
Psychiatric health and symptom severity in GvHD patients
This study looks at how graft-versus-host disease (a complication after a bone marrow transplant) affects mental health and symptom severity. It aims to understand the connection so that doctors can better support patients.
Gdansk, Pomeranian VoivodeshipAges 18–75 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT07480668Recruiting
Aromatherapy for emotional wellness during IVF
This study tests whether inhaling lavender essential oil can help reduce anxiety, stress, and depression for women waiting for IVF. You may benefit if you are feeling some emotional distress and are not using other mind-body or herbal treatments.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07493317RecruitingPhase 2
Tocilizumab for depression with inflammation
This trial tests a medication called tocilizumab, which targets inflammation, to see if it can improve symptoms of major depression in people with signs of inflammation. You may be eligible if you have depression with a high monocyte count and significant loss of interest or pleasure.
New York, New YorkAges 18–70 - NCT07538427Recruiting
Music Therapy for Health in Rural Elder Care
This study explores whether music can improve health and wellbeing in older adults living in rural care facilities. Researchers will work with residents to understand how music might help with mood, memory, and quality of life.
Flagstaff, ArizonaAges Any age - NCT07371065Enrolling by invitationPhase 1
Testing a new drug's safety in healthy adults
This trial tests a new medicine called LY03021 in healthy volunteers to see how safe it is, how the body processes it, and if food changes its effects. It's for people who are generally healthy and not taking other medications.
ShanghaiAges 18–45 - NCT07369180Enrolling by invitation
TMS for treatment-resistant depression in adults
This study tests a new type of transcranial magnetic stimulation (TMS) for adults whose depression hasn't gotten better with medication. It compares the real treatment to a sham (inactive) version to see how well it works.
Campbell, CaliforniaAges 22–85 - NCT07345858Enrolling by invitation
Saliva test for psychedelic depression treatment
This trial tests whether a simple saliva test can measure oxytocin levels during a psychedelic treatment for hard-to-treat depression. The goal is to find a biological marker that helps predict how well the therapy works.
GenevaAges 18 years+ - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT04040062Enrolling by invitation
Tested deep brain–stimulating treatment for hard-to-treat depression
This study tests a specialized type of magnetic brain stimulation (spectral TMS) to treat severe major depression when standard treatments haven’t worked. You may be eligible if you’ve tried several antidepressants and other add-on treatments but still have symptoms.
Los Angeles, CaliforniaAges 18–65 - NCT05866991Recruiting
Study tracking sleep and mood in depression
This study looks at people with a current episode of major depression and measures sleep and daily body-clock patterns, along with other mental health symptoms. They may help researchers better understand how sleep and mood changes relate, which could improve future care.
ParisAges Any age - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT06142955Recruiting
TMS therapy for depression in autism spectrum disorder
This study tests whether transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique, can help treat depression in people with autism spectrum disorder. It may help if you are between 18 and 40, have autism and depression, and are not taking medications that could interfere.
New Haven, ConnecticutAges 18–40 - NCT07721753Recruiting
Online exercise and therapy for breast cancer mood
This study tests an online program that combines fun video-game exercises with talk therapy to help breast cancer patients who feel depressed or anxious. It takes place in Malaysia and is for Chinese-speaking adults.
Xinxiang, HenanAges 18 years+ - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65
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Common questions
- Are there clinical trials for depressive disorder?
- Yes. Clin2 currently lists 689 recruiting depressive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.