Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06260891RecruitingPhase 2
Zinc study for sickle cell disease and bone health
This study tests if taking zinc supplements can improve bone health in people with sickle cell disease. It's for those with certain types of sickle cell disease (SS or S-Beta zero thalassemia) who are not on chronic transfusions or zinc supplements.
Oakland, CaliforniaAges 15–40 - NCT06274528RecruitingPhase 2
DORA and lemborexant in Alzheimer's biomarkers study
This study is testing whether a sleep medication called lemborexant can improve sleep and reduce Alzheimer's-related proteins in healthy older adults with no memory problems. It could help find new ways to delay or prevent Alzheimer's disease.
St Louis, MissouriAges 65 years+ - NCT06255886RecruitingPhase 4
Treatment for acid reflux in babies under 1 year
This trial tests a treatment for babies under 1 year old who have frequent and troublesome reflux (GERD). It aims to find a safe and effective way to reduce symptoms like crying, feeding problems, and breathing pauses.
Aabenraa, Region SyddanmarkAges 1 month–1 year - NCT06266663Recruiting
IBD study on social factors, medications, and quality of life
This study looks at how social and economic factors (like where you live and your access to care) affect medication use and quality of life for people with inflammatory bowel disease. By completing an online survey, you can help researchers understand these connections better.
New York, New YorkAges 18 years+ - NCT06267859Enrolling by invitationEarly Phase 1
Better treatment for common childhood illnesses
This study aims to improve treatment for children with common illnesses like bronchitis and for those who get sick often, to help them recover faster and stay healthier.
Tashkent, Yunus-obad DistrictAges 3 days–15 years - NCT06270316RecruitingPhase 1/Phase 2
Gene therapy for classic Fabry disease
This trial tests a one-time gene therapy called AMT-191 for men with classic Fabry disease who are still having symptoms despite enzyme replacement therapy. The goal is to see if it can reduce pain and stomach problems and improve overall health.
Birmingham, AlabamaAges 18–65 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT06233461RecruitingPhase 2
A study of TAK-279 for Crohn's disease
This study tests an oral medication called TAK-279 to see if it can safely reduce inflammation in the bowel for people with moderate to severe Crohn's disease who haven't had success with other treatments.
Murrieta, CaliforniaAges 18–75 - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06235112Recruiting
AI Screening for Heart Calcium from Chest CT Scans
This research study uses an artificial intelligence program to screen old chest CT scans for calcium buildup in the heart arteries. If you are between 40 and 75 and have had a chest CT in the last 3 years, this may help identify if you are at risk for heart disease so you can take steps to prevent it.
Boston, MassachusettsAges 40–75 - NCT06243848Recruiting
Injection vs. surgery for carpal tunnel syndrome
This trial compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection and a surgery to take pressure off the median nerve. It aims to see which one provides better relief for symptoms like numbness and tingling.
AfyonkarahisarAges 18–75 - NCT06252493Recruiting
PET/MR scan for Crohn's disease scar tissue
This study is testing a new imaging method that uses a special PET/MR scan to see how active Crohn's disease is in your bowel. The scan uses a harmless radioactive tracer that attaches to scar tissue, which may help doctors better understand the disease and guide treatment.
Charlestown, MassachusettsAges 18–99 - NCT06237868Recruiting
TMS for Impulse Control in Parkinson's Disease
This trial tests whether a type of non-invasive brain stimulation called TMS can help reduce impulse control problems (like gambling or compulsive eating) that are caused by Parkinson's medications. It's for people with Parkinson's who are living with these side effects.
Morgantown, West VirginiaAges 18 years+ - NCT06234995RecruitingPhase 4
Brain activity and movement control in Parkinson's
This study looks at how the brain controls movement in people with Parkinson's disease, including those who have had deep brain stimulation (DBS) surgery. It involves recording brain activity and may help doctors understand how to improve treatment.
Atlanta, GeorgiaAges 45–75 - NCT06248073Recruiting
Online program and task training for Parkinson's disease
This study tests an online program and task-based training to help people with mild Parkinson's disease improve their movement and reaching ability. It is designed for people who can still sit and reach for objects without major tremors or other health problems.
Linkou DistrictAges 45–70 - NCT06247150Recruiting
Study of immune cells in graft-versus-host disease after stem cell transplant
This study looks at immune cells in tissues affected by chronic graft-versus-host disease (cGVHD), a common complication after a stem cell transplant. It aims to better understand the condition, which may lead to better treatments.
PessacAges 18 years+ - NCT06235645Recruiting
Detecting lung disease in rheumatoid arthritis with ultrasound
This study tests if a lung ultrasound can detect early signs of lung disease in people with rheumatoid arthritis. It may help you if you have certain risk factors, like being male, older, or a smoker.
ToursAges 18 years+ - NCT02929732Recruiting
Study muscle nerve activity in restless legs
This study looks at how active the nerves are in people with Willis-Ekbom disease (restless legs syndrome) and compares them with people without it. It may help researchers understand what drives symptoms and how the condition works in the body.
MontpellierAges 18–74 - NCT06206616Recruiting
Liver fat in children with celiac disease
This study looks at whether children with celiac disease have fat buildup in the liver. It aims to help doctors understand and manage this condition better.
Palermo, PalermoAges 1–14 - NCT06209684Recruiting
Carbon fiber screws vs titanium for spine surgery
This trial compares a new carbon fiber screw system to standard titanium screws for people needing spinal fusion surgery to treat degenerative spine conditions. It aims to see which type of screw works better for pain and stability.
BolognaAges 18 years+ - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT06223750Enrolling by invitation
Virtual kidney check for First Nations in Manitoba
This study offers a virtual kidney health check for First Nations adults in Manitoba who haven't been recently screened. The goal is to catch early signs of kidney disease to help prevent future problems.
WinnipegAges 18 years+ - NCT06226844Recruiting
Can a vibration device help people with leg artery disease walk further?
This study tests a device called BeatMove to see if it can improve walking distance for people with blocked leg arteries that cause pain when walking. It may help if you have this condition and already take medicines for it.
NîmesAges 18 years+ - NCT06221254Recruiting
Smartphone app for emotional wellbeing in Crohn's
This study tests a smartphone app designed to help people with Crohn's disease feel better emotionally. You'll use the app at home, and researchers will see if it improves your wellbeing.
BeershebaAges 18–75
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,374 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.