Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03319446Enrolling by invitation
Sharing anonymous samples for a diagnostic test
This trial collects and stores anonymous samples from consenting adults. It helps researchers evaluate or improve diagnostic testing without using your personal identity.
Salt Lake City, UtahAges 18–99 - NCT03429036Recruiting
Collecting head and neck tissue samples for research
This study collects tissue and fluid samples from people with head and neck disorders to help researchers learn more about these conditions. By donating leftover samples from your regular medical care, you can help advance research without extra procedures.
Washington D.C., District of ColumbiaAges 3–120 - NCT03300830Recruiting
Testing tumors linked to viruses, HIV, and immune disorders
This study collects and analyzes tumor tissue to learn what drives certain cancers and growths linked to viruses, HIV, and immune system problems. Results may help researchers understand disease causes and point to better future treatments.
Bethesda, MarylandAges 18 years+ - NCT03353584Recruiting
Virtual reality for pain relief during sickle cell pain crises
This trial tests whether a virtual reality (VR) experience can help reduce pain during a sickle cell “vaso-occlusive crisis,” which is an episode of sudden, severe pain. It’s offered alongside the care team’s usual pain management to see if VR makes pain feel better.
Memphis, TennesseeAges 6–25 - NCT03297775Recruiting
Studying rheumatoid arthritis treatment risks for lung scarring
This trial is for people with rheumatoid arthritis (RA) who are at risk for developing interstitial lung disease, which is scarring in the lungs. It aims to better understand why this happens and how to help prevent or manage it.
Aurora, ColoradoAges 45–90 - NCT03503331RecruitingPhase 2
Alzheimer’s imaging add-on for research center patients
This study adds special brain scans (MRI and a PET scan) for people already enrolled in the UAB Alzheimer’s Disease Center research program. The scans are used to learn more about brain changes in Alzheimer’s, which may help researchers find better ways to measure and understand the disease.
Birmingham, AlabamaAges 50 years+ - NCT03478826Recruiting
Donate blood samples for a lung disease research biobank
This study builds a “biobank,” a storage of blood and related samples, from people with lung interstitial lung diseases or other lung scarring diseases. Your samples help researchers study these conditions and improve future care.
Rochester, MinnesotaAges 18 years+ - NCT03334292Recruiting
Study of the natural course of Wilson disease
This study follows people who already have Wilson disease to understand how the condition changes over time. It may help researchers better predict future symptoms and improve care.
New Haven, ConnecticutAges Any age - NCT03458195Recruiting
Crohn’s surgery follow-up for ileocecal resection patients
This study follows adults with Crohn’s disease who need surgery to remove the ileocecal area. It aims to better understand post-operative outcomes and what to expect after the operation.
LiègeAges 18–100 - NCT03395509Enrolling by invitation
Free screening program for diabetes and heart risks
This study looks at how well and how cost-effective a combined health screening is for diabetes and cardiovascular (heart and blood vessel) risks. You may be invited to attend screening around your 67th birthday.
ViborgAges 67–67 - NCT03450603Recruiting
Predicting COPD flare-up risk in adults
This study looks at factors that can predict when chronic obstructive pulmonary disease (COPD) will flare up. It may help doctors identify people at higher risk sooner and tailor care to prevent flare-ups.
ShanghaiAges 40 years+ - NCT03457493RecruitingPhase 1/Phase 2
TSPO brain scan study in Parkinson’s disease
This trial looks at brain inflammation in people with Parkinson’s using a special PET scan. The goal is to understand how brain immune activity may relate to Parkinson’s, and how the scan results change over time.
Birmingham, AlabamaAges 30 years+ - NCT03399175Recruiting
Early immune-suppressing treatment for VKH eye disease
This trial studies giving immune-suppressing treatment early in Vogt-Koyanagi-Harada (VKH) disease to see if it improves outcomes. It may help people reduce ongoing eye inflammation if they qualify and can be followed for a longer time.
São Paulo, São PauloAges 10–70 - NCT03388476Enrolling by invitation
Breathing carbon dioxide measurement to detect lung high blood pressure
This trial tests whether measuring carbon dioxide you breathe out can help detect pulmonary hypertension earlier. It may help doctors spot this lung blood vessel condition sooner, especially around the time you get a heart test.
Giessen, HesseAges 18 years+ - NCT03376165Recruiting
Study heart rhythm problems after heart surgery
This trial looks at heart rhythm issues (especially atrial fibrillation) that can happen after certain heart procedures. It may help doctors better predict, prevent, or manage these rhythm problems after surgery.
LilleAges 18 years+ - NCT03162549Enrolling by invitation
Inflammatory bowel disease registry for adults on biologics or JAKs
This study is a real-world registry that collects information about people with Crohn’s disease or ulcerative colitis who take certain medicines (biologics or tofacitinib). It helps researchers better understand how these treatments are used and how people are doing over time.
Waltham, MassachusettsAges 18 years+ - NCT03167203Enrolling by invitationPhase 1/Phase 2
Safety check after stem-cell eye treatment
This study follows people who previously received an embryonic stem-cell–derived treatment for macular (central) vision loss. Its goal is to watch for long-term side effects and better understand how safe the treatment is over time.
Kansas City, MissouriAges 18 years+ - NCT03291223Recruiting
Gaucher disease patient survey to improve outcomes
This study looks at how Gaucher disease affects patients’ daily life and health outcomes through a survey. Your answers could help improve future care and treatments by showing what outcomes matter most.
Lexington, MassachusettsAges Any age - NCT03178630Recruiting
MRI scans to track outcomes in children with autoimmune liver disease
This study uses MRI scans to find “biomarkers,” or imaging clues, that may help predict how autoimmune liver conditions will progress in children and young adults. If you qualify, you may get MRI imaging to see whether it relates to future health outcomes.
Cincinnati, OhioAges 6–23 - NCT03049254Recruiting
Registry and blood/tissue study for certain sudden heart death causes
This study builds a registry and collection of samples to better understand families affected by sudden heart death and related heart rhythm problems that are not clearly caused by a heart attack. It may help researchers identify patterns and improve future care, and it offers a way for patients and families to contribute to research.
Rochester, MinnesotaAges Any age - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT03035851Recruiting
Exercise program for older adults at risk of memory decline
This trial tests whether a structured aerobic (heart-pumping) exercise program can improve memory and thinking in older adults who feel memory trouble but have not been diagnosed with dementia. It focuses on people who are “at increased risk” due to common health factors like high blood pressure or diabetes.
Calgary, AlbertaAges 50–80 - NCT03214354RecruitingPhase 2
Stem cell transplant for children with sickle cell and ABO mismatch
This trial studies a stem cell transplant approach for children with sickle cell disease, using a sibling donor whose blood type is not compatible. It aims to see if this transplant method can safely reduce serious sickle cell complications.
Calgary, AlbertaAges 1–19 - NCT03295279Enrolling by invitation
Use of chest CT scans from WTC Health Plan participants
This study creates a research archive of chest CT scan images from people enrolled in the World Trade Center (WTC) Health Plan program at Mount Sinai. It may help doctors and researchers better understand and track chest health over time using existing scan images.
New York, New YorkAges 18 years+
Hear when a new Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,374 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.