Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT05597410Recruiting
Study of people at risk for Alzheimer’s in Shanghai
This study follows people who are closely related to someone diagnosed with Alzheimer’s to see who develops memory or brain changes over time. It may help researchers understand risk and early signs, which could guide prevention in families like yours.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT05610098Recruiting
Study of gene activity in spinal tuberculosis
This trial looks at patterns of gene activity (from blood/tissue samples) in adults with spinal tuberculosis. The goal is to better understand the disease and how to tell different conditions apart, which may help future care.
Cape Town, Western CapeAges 18 years+ - NCT05655650Recruiting
Finding blood or brain markers in Alzheimer’s disease
This study looks for “biomarkers,” or measurable signs, that help identify Alzheimer’s disease. It may help doctors diagnose Alzheimer’s more accurately by comparing people with Alzheimer’s to others where the diagnosis is different.
Hong Kong, Hong HongAges 20 years+ - NCT05659901Recruiting
Study tracks symptoms and test results in PLP1-confirmed PMD
This study follows children with Pelizaeus-Merzbacher disease (PMD) who have a specific genetic change (PLP1 duplication). It aims to learn which body measurements (“biomarkers”) and symptoms change over time, to better understand disease progression.
Atlanta, GeorgiaAges 6 months–17 years - NCT05670301Recruiting
Blood test study to profile inflammation biomarkers in diseases
This study measures blood “biomarkers” (signals in blood) to better understand inflammatory diseases, including autoimmune and autoinflammatory conditions. You may be asked to give blood samples now and possibly extra samples if needed for testing.
AntwerpAges Any age - NCT05683093Recruiting
Follow-up study for adults after hypertensive pregnancy
This study follows young adults who previously joined the ALSPAC study to better understand long-term heart and metabolic health after a pregnancy affected by high blood pressure. You may be asked to return for visits and possibly an MRI, and your data may help researchers plan better long-term care.
Oxford, OxfordshireAges 30–40 - NCT05689255Recruiting
Study gut bacteria and gut chemistry after gallbladder treatment
This study looks at how your gut bacteria and gut chemical products change after treatment for gallstones. It may help researchers understand what drives symptoms and recovery after surgery and/or endoscopic procedures.
Singapore, SingaporeAges 21–80 - NCT05746039RecruitingPhase 1/Phase 2
Testing semaglutide for advanced lung disease
This study checks whether semaglutide is safe and feasible for people with advanced lung diseases and higher body weight. It may help by testing a structured treatment approach, but it includes several health and safety limits.
Philadelphia, PennsylvaniaAges 18–80 - NCT05773638Recruiting
Study blood clots and heart disease in adults with Von Willebrand
This study looks at cardiovascular problems and blood-clot events (like deep vein clots or pulmonary embolism) in adults with Von Willebrand disease in western France. It may help doctors better understand who is at risk and how to manage these complications.
AngersAges 18 years+ - NCT05807256Recruiting
Fertility treatments for people with immune system joint diseases
This trial looks at fertility (“medically assisted fertilization,” such as IVF) for people with certain immune-related rheumatology conditions (like lupus, rheumatoid arthritis, or vasculitis). It may help patients and their clinicians understand which fertility approach works best and is safe for this group.
MilanAges 18–50 - NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Little Rock, ArkansasAges 18 years+ - NCT05819385Recruiting
Study of lung scarring in immune diseases
This is an observational (non-treatment) study that collects information about how interstitial lung disease (lung scarring) happens in people with certain autoimmune or immune-related conditions. It uses patient interviews or existing medical records to better understand the pattern and causes, which may help future care.
Mexico CityAges 18 years+ - NCT05829889Recruiting
FFR test versus angiogram to guide left main heart treatment
This trial compares two ways to decide how to treat a narrowed “left main” coronary artery: a pressure-based test (FFR) versus standard X-ray imaging (angiography). It aims to see which approach better helps choose safe, appropriate treatment using a stent when appropriate.
Hong KongAges 20 years+ - NCT05835973Recruiting
Study of sleep changes in people with inflammatory bowel disease
This study looks at how sleep patterns change in adults with inflammatory bowel disease (IBD) who are currently in remission. It may help researchers understand sleep issues in IBD and identify ways to improve care during symptom-free periods.
Clermont-FerrandAges 18–65 - NCT05854563Recruiting
Study using collected cough samples to learn about lung disease
This trial looks at “cough capture” samples to better understand what is happening in the lungs. You might be eligible if you’re having a bronchoscopy for medical reasons and don’t already have lung cancer.
The Bronx, New YorkAges 21 years+ - NCT05871216Recruiting
Study of joint instability in people with loose joints
This trial is testing how to assess and manage joint instability in people who have unusually loose (hypermobile) joints. If you have moderate to severe loose joints, you may be able to join after screening checks like movement tests and health history.
BolognaAges 18–60 - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05884944Recruiting
Osteopathic massage study for leg muscle in Parkinson’s disease
This trial studies whether osteopathic manipulative medicine (gentle hands-on treatment) can change how leg muscles work in people with Parkinson’s disease. It may help with leg pain, cramping, or walking problems caused by Parkinson’s.
Old Westbury, New YorkAges 18 years+ - NCT05895487Recruiting
UniLine heart valve replacement study for aortic or mitral disease
This trial studies how well a specific bioprosthetic heart valve (“UniLine”) works after surgery, including safety and how long it lasts. You may be able to join if you are an adult getting a first-time mitral or aortic valve replacement with this exact valve.
KemerovoAges 18 years+ - NCT05904301Recruiting
Registry for autoimmune and autoinflammatory disease patients
This study builds a nationwide list (registry) of people with certain autoimmune or inflammation-related illnesses. It helps researchers understand these diseases better over time, which can guide future care.
YerevanAges Any age - NCT05908279Recruiting
Walking and gait study in people with Parkinson’s disease
This trial studies walking patterns and how walking is controlled in people with Parkinson’s disease. It may help researchers understand movement control and improve future therapies by comparing walking ability and patterns.
Louvain-la-NeuveAges 18–99 - NCT05908266Recruiting
Training control for reaching in Parkinson disease
This study tests a way to help people control reaching movements during a task. You may be able to join if you can understand the instructions and successfully perform the reaching task during the experiment.
Louvain-la-NeuveAges 18–99 - NCT05927454Recruiting
RaDiCo Acostill study for inflammatory fevers and arthritis
This is a long-term study that collects health information and lab samples from people who have certain diagnoses of recurring (coming and going) inflammatory fevers and related joint or immune conditions. It may help researchers better understand these diseases and how they work over time.
Paris, Île-de-France RegionAges Any age
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,506 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.